| Project/Area Number |
18591351
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyushu University |
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Principal Investigator |
YOSHIURA Takashi Kyushu University, 大学病院, 講師 (40322747)
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| Co-Investigator(Kenkyū-buntansha) |
MIHARA Futoshi 九州大学, 医学研究院, 准教授 (80253615)
KUMAZAWA Seiji 九州大学, 医学研究院, 助教 (50363354)
NOGUCHI Tomoyuki 九州大学, 大学病院, 助教 (40380448)
HONDA Hiroshi 九州大学, 医学研究院, 教授 (90145433)
ARIMURA Hidetaka 九州大学, 医学研究院, 准教授 (20287353)
KOGA Hiroshi 九州大学, 大学病院, 助教
HIWATASHI Akio 九州大学, 医学研究院, 助教 (30444855)
TANAKA Kazuhiro 九州大学, 大学病院, 助教 (70448421)
MONJI Akira 九州大学, 大学病院, 講師 (00294942)
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| Project Period (FY) |
2006 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,890,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥690,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2006: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | 脳・神経 / 脳神経疾患 / MRI / 拡散テンソル画像 / 認知症 / 神経ネットワーク / 脳 / 神経回路 / 拡散テンソル / 白質路 / 大脳皮質 / 痴呆 / 老化 / 可視化 |
|---|
| Research Abstract |
We have developed a new method based on diffusion tensor MR imaging to quantitatively visualize brain network consisting of cerebral cortices interconnected by the white matter pathways. Using our method, we evaluated regional variations and age-related changes in cerebral microstructure. Moreover, we evaluated damages in the brain network due to Alzheimer's disease, and revealed that our method is useful in diagnosing Alzheimer's disease.
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