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Development of techniques for increasing the accuracy of dose calculation in a convolution method used for body stereotactic radiotherapy

Research Project

Project/Area Number 18591375
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHirosaki University

Principal Investigator

IWASAKI Akira  Hirosaki University, Hirosaki University, Graduate School of Health Sciences, Professor (60111233)

Co-Investigator(Kenkyū-buntansha) HIROTA Junichi  Hirosaki University, Graduate School of Health Sciences, Associate Professor (00333732)
KUBOTA Mamoru  Hirosaki University, Graduate School of Health Sciences, Assistant Professor (80133891)
ABE Yoshinao  Hirosaki University, Graduate School of Medicine, Professor (10167950)
Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2006: ¥2,400,000 (Direct Cost: ¥2,400,000)
KeywordsCovolution method / High-energy X-rays / Stereotactic radiotherapy / X-ray spectrum / Kernel / Error function / Multileaf collimator / Radiation therapy physics / 線源軸外線量比 / 軸外コリメータ散乱係数 / リーフ照射野出力差分法 / 高エネルギーX線スペクトル
Research Abstract

The following studies have been performed:
・High-energy x-ray spectra sets from six linear accelerators were reconstructed using about ten energy bins. Each set can be applied accurately to attenuators from low Z materials like water to high Z materials like lead. It was analyzed how each set varies with the off-axis distance.
・A pair of primary and scatter dose kernels in water was constructed for monochromatic radiation at each energy bin using Monte Carlo simulations on the basis of the differential method. The primary dose kernel indicates relatively smaller values around the photon interaction point, when compared with a primary dose kernel yielded with a photon interaction point at the center of a large water phantom. This fact may leads to the increase of dose calculation accuracy around the jaw and MLC field borders when using primary dose kernels based on the differential method.
・The in-water doses, calculated using a convolution method with sets of primary and scatter dose kernels yielded for respective energy bins, are generally within ±1% when compared with measurements. Namely, it can be understood that when the convolution is performed for monochromatic radiation at each energy bin, the beam hardening effect does not need to be taken into account.
・With respect to the calculation of in-air x-ray intensity at a point, a method of using error functions on the x-ray target and flattening filter planes has been developed. For an open jaw field, the error functions are used in the area visual via the jaw collimators from the point. For an MLC field, a leaf-field output subtraction method is introduced using the error functions in the area visual via the jaw collimators from the point and using the error functions in the are a visual via each MLC leaf from the point.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (15 results)

All 2007 2006

All Journal Article (4 results) Presentation (11 results)

  • [Journal Article] X線スペクトルに基づいてモンテカルロシミュレーションで構築した高エネルギーX線一次及び散乱ドーズカーネルの開発2007

    • Author(s)
      笹森真実, 岩崎晃, 齋藤秀敏, 木村重伸, 清野守央, 駒井史雄
    • Journal Title

      弘前大学医学部保健学科紀要 6巻

      Pages: 101-114

    • NAID

      110006225014

    • Related Report
      2006 Annual Research Report
  • [Journal Article] MLC不整形照射野におけるコリメータ散乱係数(Sc)を算出する二つの近似法2006

    • Author(s)
      奈良鉄造, 岩崎 晃, 駒井史雄, 佐藤和彦, 福士英人, 洞内美明
    • Journal Title

      日本放射線技術学会誌 62・7

      Pages: 961-970

    • Related Report
      2006 Annual Research Report
  • [Journal Article] New Development of High-Energy X-Ray Primary and Scatter Dose Kernels by Monte Carlo Simulation2006

    • Author(s)
      Makoto Sasamori, Akira Iwasaki, Hidetoshi Saitoh, Shigenobu Kimura, Morio Seino, Fumio Komai
    • Journal Title

      Proceedings of the Thirteenth EGS Users' Meeting in Japan (KEK, Tsukuba, Japan)

      Pages: 53-65

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Characteristic features of a high-energy x-ray spectra estimation method based on the Waggener iterative perturbation principle2006

    • Author(s)
      Akira Iwasaki, Mamoru Kubota, Junichi Hirota, Akira Fujimori, Katsumasa Suzaki, Masahiko Aoki, Yoshinao Abe
    • Journal Title

      Medical Physics 33 ・ 11

      Pages: 4056-4063

    • NAID

      10027060643

    • Related Report
      2006 Annual Research Report
  • [Presentation] Proposals to improve the accuracy of convolution-based dose calculation2007

    • Author(s)
      Akira Iwasaki, Shigenobu Kimura, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Calculation of MLC in-air outputs using a leaf-field output subtraction method2007

    • Author(s)
      Shigenobu Kimura, Akira Iwasaki, Kohji Sutoh, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Introduction of an off-axis collimator scatter factor (S_C) and a source off-center ratio (OCR_<source>) for calculation of off-axis in-air outputs2007

    • Author(s)
      Fumio Komai, Akira Iwasaki, Shigenobu Kimura, Morio Seino, Makoto Sasamori
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Monte Carlo simulation for constructing dose kernels based on the differential dose concept2007

    • Author(s)
      Makoto Sasamori, Akira Iwasaki, Hidetoshi Saitoh, Shigenobu Kimura, Morio Seino^I, Fumio Komai
    • Organizer
      15th International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Proposals to improve the accuracy of convolution-based dose Calculation2007

    • Author(s)
      Akira Iwasaki, Shigenobu Kimura, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      Hilton Hotel, Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Calculation of MLC in-air outputs using a leaf-field output subtraction method2007

    • Author(s)
      Shigenobu Kimura, Akira Iwasaki, Kohji Sutoh, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      Hilton Hotel, Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Introduction of an off-axis collimator scatter factor (S_c) and a source off-center ratio (OCR_<source>) for calculation of off-axis in-air outputs2007

    • Author(s)
      Fumio Komai, Akira Iwasaki, Shigenobu Kimura, Morio Seino, Makoto Sasamori:
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      Hilton Hotel, Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Monte Carlo simulation for constructing dose kernels based on the differential dose concept2007

    • Author(s)
      Makoto Sasamori, Akira Iwasaki, Hidetoshi Saitoh, Shigenobu Kimura, Morio Seino^1, Fumio Komai
    • Organizer
      15^<th> International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      Hilton Hotel, Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Proposals to improve the accuracy of convolution-based dose calculation2007

    • Author(s)
      Akira Iwasaki, Shigenobu Kimura, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15th International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Related Report
      2007 Annual Research Report
  • [Presentation] Calculation of MLC in-air outputs using a leaf-field output subtraction method2007

    • Author(s)
      Shigenobu Kimura, Akira Iwasaki, Kohji Sutoh, Morio Seino, Fumio Komai, Makoto Sasamori
    • Organizer
      15th International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Related Report
      2007 Annual Research Report
  • [Presentation] Introduction of an off-axis collimator scatter factor(S_C)and a source off-center ratio(OCR_<source>)for calculation of off-axis in-air outputs2007

    • Author(s)
      Fumio Komai, Akira Iwasaki, Shigenobu Kimura, Morio Seino, Makoto Sasamori
    • Organizer
      15th International Conference on the Use of Computers in Radiation Therapy
    • Place of Presentation
      カナダ(トロント、ヒルトンホテル)
    • Related Report
      2007 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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