Boron neutron capture therapy for malignant pleural mesothelioma
| Project/Area Number |
18591379
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
SUZUKI Minoru Kyoto University, 原子炉実験所・附属粒子線腫瘍学研究センター, 准教授 (00319724)
|
|---|
| Project Period (FY) |
2006 – 2008
|
| Project Status |
Completed (Fiscal Year 2008)
|
| Budget Amount *help |
¥3,970,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥570,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2006: ¥1,500,000 (Direct Cost: ¥1,500,000)
|
|---|
| Keywords | 悪性胸膜中皮腫 / 硼素中性子捕捉療法 |
|---|
| Research Abstract |
手術不能である悪性胸膜中皮腫に対する新規治療方法として、硼素中性子捕捉療法の適用が可能であるか否かの基礎的検討を実施した.悪性中皮腫モデルマウスを用いて硼素中性子捕捉療法が重篤な肺障害を与えず、中皮腫の縮小効果と生存期間を延長させることを明らかにした.また、治療計画研究を実施し正常肺への耐容線量以下で、腫瘍に対して治療効果が期待される線量を投与することが可能であることを明らかにした.
|
Report
(4 results)
Research Products
(52 results)
-
[Journal Article] Survival benefit of boron neutron capture therapy for recurrent malignant gliomas2009
Author(s)
Miyatake SI, Kawabata S, Yokoyama K, Kuroiwa T, Michiue H, Sakurai Y, Kumada H, Suzuki M, Maruhashi A, Kirihata M, Ono K
-
Journal Title
J Neurooncol 91(2)
Pages: 199-206
Related Report
Peer Reviewed
-
-
[Journal Article] Treatment results of boron neutron capture therapy using intra-arterial administration of boron compounds for recurrent head and neck cancer2008
Author(s)
Fuwa N, Suzuki M, Sakurai Y, Nagata K, Kinashi Y, Masunaga S, Maruhashi A, Imahori Y, Kodaira T, Tachibana H, Nakamura T, Ono K
-
Journal Title
Br J Radiol 81(969)
Pages: 749-52
Related Report
Peer Reviewed
-
[Journal Article] A novel concept of treatmentof diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT)2008
Author(s)
Suzuki M, Endo K, Satoh H, Sakurai Y, Kumada H, Kimura H, Masunaga S, Kinashi Y, Nagata K, Maruhashi A, Ono K
-
Journal Title
Radiother Oncol 88
Pages: 192-195
Related Report
Peer Reviewed
-
-
[Journal Article] Radiobiological significance of the response of intratumor quiescent cells in vivo to accelerated carbon ion beams compared with γ-rays and reactor neutron beams2008
Author(s)
Masunaga S, Ando K, Uzawa K, Hirayama R, Furusawa Y, Koide S, Sakurai Y, Nagata K, Suzuki M, Kashino G, Kinashi Y, Tanaka H, Maruhashi, Ono K
-
Journal Title
Int. J. Radiat. Oncol. Biol. Phys 70(1)
Pages: 221-228
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] Impact of intra-arterial administration of boron compounds on dose-volume histograms (DVHs) in boron neutron capture therapy (BNCT) for recurrent head and neck tumors2006
Author(s)
Suzuki M, Sakurai Y, Nagata K, Kinashi Y, Masunaga S, Ono K, Maruhashi A, Kato I, Fuwa N, Hiratsuka J, Imahori Y
-
Journal Title
Int. J. Radiat. Oncol. Biol. Phys 66(5)
Pages: 1523-1527
Related Report
Peer Reviewed
-
[Journal Article] Impact of accelerator-based boron neutron capture therapy (AB-BNCT) on the treatment of multiple liver tumors and malignant pleural mesothelioma
Author(s)
Suzuki M, Tanaka H, Sakurai Y, Kashino G, Yong L, Masunaga S, Kinashi Y, Mitsumoto T, Yajima S, Tsutsui H, Sato T, Maruhashi A, Ono K
-
Journal Title
Radiother Oncol (In press)
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
