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The treatment strategy of bronchial dysplasia using a novel autofluorescence imaging bronchovideoscope system and microarray

Research Project

Project/Area Number 18591541
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionChiba University

Principal Investigator

SHIBUYA Kiyoshi  Chiba University, university hospital, Associate professor (20302565)

Co-Investigator(Kenkyū-buntansha) SUZUKI Makoto  Chiba University, Graduate school of medicine, Assistant professor (80312940)
IYODA Akira  Chiba University, university hospital, Assistant professor (10302548)
YASUFUKU Kazuhiro  Chiba University, university hospital, Assistant professor (60372356)
NAKAJIMA Takahiro  Chiba University, university hospital, Assistant professor (20400913)
SEKI Naohiko  Chiba University, Graduate school of medicine, Associate professor (50345013)
藤澤 武彦  千葉大学, 大学院医学研究院, 教授 (80110328)
Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,860,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2006: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsAFI / NBI / high resolution bronchovideoscopy / bronchial dysplasia / PET
Research Abstract

Using autofluorescence imaging bronchovideoscope system (AFI) and a high resolution bronchovideoscopy system with narrow band imaging (NBI), we followed up periodically localized bronchial dysplasias and examined for positron emission tomography scanning (PET) with F-18 fluorodeoxyglucose, with the maximum standard uptake value measured. Fifty-three dysplasias mainly with sputum cytology suspicious or positive for malignancy and lung cancer patients were followed up. Of 53 dysplasias, no dysplasias progressed to squamous cell carcinoma. PET identified only two spot in 34 follow up, which are diagnosed as one squamous cell carcinoma and inflammatory tumor. There were no early hilar lung cancers and severe dysplasias only PET findings.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (12 results)

All 2007 2006 Other

All Journal Article (7 results) (of which Peer Reviewed: 3 results) Presentation (3 results) Book (2 results)

  • [Journal Article] Cytological findings of pre-invasive bronchial lesions detected by light-induced fluorescence fluorescence endoscopy in a lung cancer screening system.2007

    • Author(s)
      Baba, M. Iyoda, A. Nomoto, Y. Shibuya, K. etc
    • Journal Title

      Oncol Rep 17

      Pages: 579-583

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 気管食道領域における内視鏡の進歩呼吸器領域の内視鏡診断2007

    • Author(s)
      渋谷 潔, 中島 崇裕, その他
    • Journal Title

      日本気管食道科学会会報 58

      Pages: 145-150

    • NAID

      130004469818

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 気管支ビデオスコープを使用する蛍光気管支内視鏡画像について2007

    • Author(s)
      中島 崇裕, 渋谷 潔, その他
    • Journal Title

      肺癌 47

      Pages: 215-221

    • NAID

      110006345496

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集 気管支鏡手技を用いた医療の最新動向 気管支鏡による肺癌早期診断技術の検討2007

    • Author(s)
      渋谷 潔, 安福和弘, その他
    • Journal Title

      呼吸と循環 55,2

      Pages: 145-154

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cytological findings of pre-invasive bronchial lesions detected by light-induced fluorescence endoscopy in a lung cancer screening system2007

    • Author(s)
      Baba, M., Shibuya, K., H.etc.
    • Journal Title

      Oncology Reports 17

      Pages: 579-583

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 気管支鏡による早期診断技術の開発2006

    • Author(s)
      藤澤武彦, 渋谷 潔, その他
    • Journal Title

      日本胸部臨床増刊号 肺癌up-to-date 65

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 「研究成果報告書概要(欧文)」より

    • Author(s)
      Baba, M., Iyoda, A., Nomoto, Y., Shibuya, K., etc.
    • Journal Title

      Cytological findings of pre-invasive bronchial lesions detected by light-induced fluorescence endoscopy in a lung cancer screening system. Oncol Rep.17

      Pages: 579-583

    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Narrow Band Imagingを用いた気管支粘膜観察の有用性2007

    • Author(s)
      渋谷 潔, 中島 崇裕, その他
    • Organizer
      日本肺癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-11-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] Recent advance in autofluorescence bronchoscopy and narrow band imaging.2007

    • Author(s)
      Shibuya, K.
    • Organizer
      The 2007 Interventional Bronchoscopy Symposium, Kaishiung, Taiwan. Symposium, Invited Special Lecture.
    • Place of Presentation
      Taiwan.
    • Year and Date
      2007-07-01
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] (2007) Recent advance in autofluorescence bronchoscopy and narrow band imaging2007

    • Author(s)
      Shibuya, K.
    • Organizer
      The 2007 Interventional Bronchoscopy Symposium, Kaishiung, Taiwan. Symposium, Invited Special Lecture
    • Year and Date
      2007-07-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 蛍光気管支内視鏡.呼吸器common diseaseの診療 肺癌のすべて2007

    • Author(s)
      渋谷 潔, 藤澤 武彦
    • Total Pages
      403
    • Publisher
      文光堂
    • Related Report
      2007 Annual Research Report
  • [Book] 肺癌診療マニュアル(江口研二編)2006

    • Author(s)
      藤澤武彦, 渋谷 潔(内視鏡的レーザー治療 分担執筆)
    • Total Pages
      323
    • Publisher
      中外医学社,東京
    • Related Report
      2006 Annual Research Report

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Published: 2006-04-01   Modified: 2021-12-08  

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