Clinical application and renovation of endovascular electrode for endovascular electroencepharogram used for the detection of the focus of epilepsy
| Project/Area Number |
18591597
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
HYODO Akio University of the Ryukyus, School of Medicine, Neurosurgery, Associate Professor (40167606)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHII Yoshihiko University of the Ryukyus, School of Medicine, Neurosurgery, Professor (50110507)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,950,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2006: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Keywords | brain / endovascular therapy / electroencepharogram / epilepsy / endovascular electrode / 脳神経 |
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| Research Abstract |
Endovascular electroencepharogram seems to be an important diagnostic tool for the detection of the focus of epilepsy existing in the deep region of the brain. However, there are several problems that we cannot conquer. The purpose of this study is to get rid of the defects of the former endovascular electrode in order to obtain safety and effectiveness of the new one after animal experiments and clinical application trials.
We made a new endovascular electrode, recording endovascular electroencepharogram of a swine. The new endovascular electrode was made from the smallest microcatheter now available. We recorded endovascular electroencepharogram of the swine with the catheter-electrode that has four multi-electrodes on the tip. We entered the endovascular electrode from the femoral artery to the skull base artery of the swine. We confirmed that the endovascular electroencepharogram was recorded, comparing with the electroencepharogram from the scalp at the same time.
We already performed more than 2,000 endovascular treatments and we have full confidence in the clinical application, but there was no case of intractable epilepsy at that time. Moreover, the main investigator was going to move to another institution, so we could not realize clinical application actually. Now we look forward to getting good clinical results in the near future.
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Report
(3 results)
Research Products
(1 results)
