| Project/Area Number |
18591897
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Kawasaki Medical School |
|---|
Principal Investigator |
SUETAKA Nishiike Kawasaki Medical School, Medical School, Associate Professor (90283762)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAKEDA Noriaki Tokushima University, School of Medicine, Professor & Chairman (30206982)
|
|---|
| Project Period (FY) |
2006 – 2007
|
| Project Status |
Completed (Fiscal Year 2007)
|
| Budget Amount *help |
¥3,890,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2006: ¥2,200,000 (Direct Cost: ¥2,200,000)
|
|---|
| Keywords | vestibular / rehabilitation / vertigo / motion sickness / sensory mismatch |
|---|
| Research Abstract |
Postural and locomotor control in unilateral labyrinthine-defective patients deviates towards the lesion side. Virtual reality, which controls sensory inputs to humans, can change the balance between vestibular and visual inputs to advance vestibulo-ocular reflex and vestibulo-spinal reflex and may stimulate vestibular compensation. In 2006, we produced virtual environment with control condition and visual-vestibular mismatch condition. In 2007, we examined the effects these conditions produced by virtual reality on ocular movement and locomotor tracks in healthy subjects. During control condition, neither locomotor deviation nor optokinetic nystagmus was observed. During the 20-min experiment with visual-vestibular mismatch condition, the mean locomotor deviation as well as the mean frequency and mean amplitude of OK nystagmus (OKN) during the last period of the experiment was significantly higher than that during the initial period. Twenty-minute-exposure to this environment was sufficient to cause adaptive change in locomotion in healthy subjects, suggesting that it promises to improve locomotor deviation in patients.
|
