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Attempt for kinetic analysis in head and neck region using enhanced MRI

Research Project

Project/Area Number 18592063
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionKyushu University

Principal Investigator

YOSHIURA Kazunori  Kyushu University, 歯学研究院, 教授 (20210643)

Co-Investigator(Kenkyū-buntansha) CHIKUI Toru  九州大学, 歯学研究院, 准教授 (10295090)
TOKUMORI Kenji  九州大学, 歯学研究院, 准助教 (40253463)
SHIMIZU Mayumi  九州大学, 歯学研究院, 助教 (50253464)
GOTO Tazuko  九州大学, 大学病院, 助教 (60294956)
KAWAZU Toshiyuki  九州大学, 大学病院, 助教 (20294960)
OKAMURA Kazutoshi  九州大学, 歯学研究院, 助教 (20346802)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,780,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥1,700,000 (Direct Cost: ¥1,700,000)
Keywords造影 / MRI / T_1値 / 造影剤濃度 / Gd造影剤 / permeability / transfer constant / T1値 / Kinetic Analysis / Lock-Locker sequence / IR-TSE法
Research Abstract

良悪性の鑑別にMRIの造影パターンを判断材料にする事が多いが、信号強度自体は撮像法により異なり、各施設で共通した指標とはなりにくい。そのため信号強度自体を解析するのではなく、信号強度から造影剤濃度を算出し、薬物動態解析(コンパートモデル解析の一種であるTofts-Kermode model (TK model)を適応)することによって、組織固有のパラメーターを算出を試みた。その為には、造影剤投与後の造影剤濃度の把握が必要であり、算出方法の確立を行った。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 2007 2006

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (8 results)

  • [Journal Article] A fast Look-Locker method for T1 mapping of the head and neck region2009

    • Author(s)
      Toru Chikui, Kenji Tokumori, RyosukeZeze, Tomoko Shiraishi, Takahiro Ichihara, Masamitsu Hatakenaka, Kazunori Yoshiura
    • Journal Title

      Oral radiol in press

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A fast Look-Locker method for Tl mapping of the head and neck region.2009

    • Author(s)
      Toru Chikui, Kenji Tokumori, Ryosuke Zeze, Tomoko Shiraishi, Takahiro Ichihara, Masamitsu Hatakenaka, Kazunori Yoshiura
    • Journal Title

      Oral radiol (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 2D-Look-Locker sequenceを使用したT_1計測の試み2007

    • Author(s)
      筑井徹、瀬々良介、市原隆洋、湯浅賢治、吉浦一紀
    • Journal Title

      歯科放射線 47(2)

      Pages: 65-74

    • NAID

      10024177303

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 2D-Look-Locker sequenceを使用したT_1計測の試み2007

    • Author(s)
      筑井 徹, 他4名
    • Journal Title

      歯科放射線 47

      Pages: 65-74

    • NAID

      10024177303

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 頭頸部におけるGd造影剤濃度の算出の試み-ファントム実験および臨床症例への適応-2008

    • Author(s)
      筑井徹、瀬々良介、市原隆洋、木原由香、湯浅賢治、吉浦一紀
    • Organizer
      日本歯科放射線学会第49回学術大会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Attempt for estimating parameters in the orofacial region by dynamic contrast-enhanced T1-weighted MRI2008

    • Author(s)
      Toru Chikui, Kenji Tokumori, Ryousuke Zeze, Takahiro Ichihara, Kazunori Yoshiura
    • Organizer
      The 7th Asian Congress of Oral and Maxillo-Facial Radiology
    • Place of Presentation
      Nara
    • Related Report
      2008 Final Research Report
  • [Presentation] Attempt for estimating parameters in the orofacial region by dynamic contrast-enhanced Tl-weighted MRI2008

    • Author(s)
      Toru Chikui, Kenji Tokumori, Ryousuke Zeze, Takahiro Ichihara, Kazunori Yoshiura.
    • Organizer
      The 7th Asian Congress of Oral and Maxillo-Facial Radiology
    • Place of Presentation
      Nara
    • Related Report
      2008 Annual Research Report
  • [Presentation] 2D-Look-Locker sequenceを使用した頭頸部T_1mapping2007

    • Author(s)
      筑井 徹, 他6名
    • Organizer
      日本歯科放射線学会第50回関西・第46回九州合同地方会
    • Place of Presentation
      大阪
    • Year and Date
      2007-12-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] T1 measurements using Look-Locker sequence.2007

    • Author(s)
      Toru Chikui, Tokumori Kenji, Ryosuke Zeze, Takahiro Ichihara, Kenji Yuasa,Kazunori Yoshiura
    • Organizer
      The 16th International Congress of Dentomaxillofacial Radiology
    • Place of Presentation
      Beijing
    • Related Report
      2008 Final Research Report
  • [Presentation] 2D-Look-Locker sequenceを使用した頭頸部T1mapping2007

    • Author(s)
      筑井徹、徳森謙二、白石朋子、瀬々良介、市原隆洋、湯浅賢治、吉浦一紀
    • Organizer
      日本歯科放射線学会第50回関西第46回九州合同地方会
    • Place of Presentation
      大阪
    • Related Report
      2008 Final Research Report
  • [Presentation] T 1 measurements using Look-locker sequence.2007

    • Author(s)
      Toru Chiku, 他5名
    • Organizer
      _17th internarional Congress of Dentomaxiillofacial Radiology
    • Place of Presentation
      Beijing
    • Related Report
      2007 Annual Research Report
  • [Presentation] Look-Locker sequenceによるT1時間測定-ファントムによる検討および頭頸部への応用-2006

    • Author(s)
      筑井徹、瀬々良介、市原隆洋、湯浅賢治、吉浦一紀
    • Organizer
      日本歯科放射線学会44回九州・第49回関西合同地方会
    • Place of Presentation
      福岡
    • Related Report
      2008 Final Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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