| Project/Area Number |
18592226
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Health Sciences University of Hokkaido (2007)
Hokkaido University (2006) |
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Principal Investigator |
HASHIMOTO Masanori Health Sciences University of Hokkaido, Division of Biomaterials and Bioengneering, Assistant Professor (00337164)
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| Co-Investigator(Kenkyū-buntansha) |
YAWAKA Yasutaka Hokkaido University, Division of Pediatric Dentistry, Professor (60230603)
KAGA Masayuki Hokkaido University, Division of Pediatric Dentistry, Associate Professor (70125300)
HASHIMOTO Masanori Health Sciences University of Hokkaido, Division of Biomaterials and Bioengineering, Assistant Professor (00337164)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,670,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2006: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | Self-healing / remineralization / bioglass / restorative dentistry / adhesive interface / microleakage / resin adhesive / glass-ionomer / 石灰化 / 象牙質 / エナメル質 / 走査型電子顕微鏡 / 透過型電子顕微鏡 |
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| Research Abstract |
A finding in this study was that crystal formation (approximately 10 μm in diameter) was a common feature of some fluoridated adhesive resins, where were separated by a standardized interfacial gap between teeth and cured materials. This crystal growth was also found in bioglass (Na_2-CaO-SiO_2-P_2O_5) -containing adhesive resins after several months of water storage. The mechanical properties of resin adhesives are completely reduced by bioglass addition. The decreasing amount of bioglass addition for adhesives prevents a reduction of mechanical property of materials but it reduces an amount of ion releasing for remineralization. The reduction of mechanical property may induced by crystal growth formation due to simultaneous response between bioglass and water. In theory, there are one possibility for increasing the surface area of bioglass per unit, and thus making them more active. An future approach may be simply to decrease glass particle size (nano-sized bioglass), and thus increase the ion exchange surface of glass and surrounding liquid, and prevent mechanical property decreasing for clinical use.
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