| Co-Investigator(Kenkyū-buntansha) |
MIYAWAKI Shoichi Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (80295807)
OHO Takahiko Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (50160940)
NAGATA Jinko Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor (50264429)
SUGIHARA Kazumasa Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (00117516)
SAKAGUCHI Kazumasa Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor (80381185)
吉田 礼子 鹿児島大学, 医学部・歯学部附属病院, 助手 (60244258)
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| Budget Amount *help |
¥3,850,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2006: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Research Abstract |
The aim of this study was to investigate the situation of sleep bruxism, periodontal disease, temporomandibular disorders and digestive symptoms caused by the gastro-esophageal reflux (GERD),and to establish the new treatment method for xerostomia, sleep bruxism and GERD using the acid reducer.
One hundred and five adults were selected from the patient who visited Kagoshima University Hospital. As the purpose of the present study, subjects were divided into two groups according to the presence or absence of xerostomia symptoms. The xerostomia symptoms were evaluated using xerostomia evaluation standard of Health, Labour and Welfare Ministry, and GERD symptoms were evaluated by self-administered questionnaire (QUEST) and F-scale. Also, situations of periodontal disease, attrition, calies and temporomandibular disorders were investigated. Twenty percent of the subjects showed the typical symptoms of xerostomia such as thirst, wants of drinking, difficulty in swallowing dry foods. Comparison between xerostomia subjects and non-xerostomia subjects indicated the significant differnces in subjective QOL, subjective symptoms of digestive disease and fatigue or discomfortness of perioral muscles. Additionally, xerostomia subjects showed respiratory symptoms, back pain, nuuropsychological symptoms such as insominia and chlonic headache significantly, compared with non-xerostomia subjects. Besides, as the result of dosing of acid reducer and directions for dietary pattern on GERD subjects who were decided from pH monitoring of esophagus for four months, degree of the gastro-esophageal reflux was improved.
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