| Project/Area Number |
18592287
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Ohu University |
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Principal Investigator |
HAMADA Setuo Ohu University, Department of Oral Medical Science, School of Dentistry, Professor (80094952)
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| Co-Investigator(Kenkyū-buntansha) |
MIYAZAWA Cyuzo Ohu University, Department of Dental Materials Science (Chemistry), School of Dentistry, Professor (70083441)
TAYA Kahoru Ohu University, Department of Oral Medical Science, School of Dentistry, Assistant (00347949)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,270,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2006: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | photo catalysts / anatite / TiHAp / OH radical / spin-trapping reagent / ラジカル / 酸化チタン / スビントラッビング剤 |
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| Research Abstract |
Hydroxyapatite (Hap) has a molecular structure in which Ca^<2+>, PO_4^<3-> and OH- are major components. When hydroxyapatite is formed the Ca^<2+>, PO_4^<3-> and OH- ions can be substituted with other specific ions. Therefore, the author performed the following experiment: The first portion of the experiment was the synthesis of Hap using the coprecipitation method substituting Ti^<4+> for Ca^<2+>. The Ti^<4+> was doped to the Ca^<2+> position in the forming hydroxyapatite crystal. In the next phase of this experiment the author analyzed whether the Hap had obtained photocatalytic function that is a major character of Ti^<4+>.
The X-ray diffraction of the TiHAp showed a reversed correlative phenomenon when anatase dioxide titanium was at 25° (2θ) and the strength of HAp was at 26° (2θ) due to the doped Ti^<4+>. Therefore, the observed change in the Hap must be a consequence of the doped Ti^<4+> into the Hap molecule. The mole ratio of the Ca/P in the synthetic substance showed that the Ti^<4+> concentration was dependent on the successful doping of Ti^<4+> for Ca^<2+>. It was observed that the more successful the dope of Ti^<4+> for Ca^<2+> the mole ratio showed a rectilinear decrease. Therefore, this observation confirmed that Ti^<4+> had replaced Ca^<2+>.
The OH radical was identified from the post ultraviolet irradiated synthesized substance. The strength of the OH radical increased when the success of the substitution of Ti^<4+> for Ca^<2+> increased.
The observation of a clear OH radical signal by ultraviolet irradiation was confirmed from the outer layers of both the polypropylene and acrylic denture base resins that had been combined with 1% of the synthesized TiHAp. It was observed that there was delayed depletion in the resins that had been combined with the synthesized TiHAp.
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