Establishment of a public health guideline for osteoporosis prevention : based on the results of a long-term follow-up study
| Project/Area Number |
18592417
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Community health/Gerontological nurisng
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| Research Institution | Nagoya University |
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Principal Investigator |
KAJITA Etsuko Nagoya University, School of Medicine, Professor (50135373)
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| Co-Investigator(Kenkyū-buntansha) |
IKI Masayuki Nagoya University, Dept Public Health School of Medicine, Professor (50184388)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,890,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2006: ¥2,200,000 (Direct Cost: ¥2,200,000)
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| Keywords | Osteoporosis / Follow-up study / Public health guideline |
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| Research Abstract |
To determine the serial changes in bone mineral density(BMD) and related lifestyle factors during a 15-year period in middle-aged women undergoing intervention since 1990. We conducted a follow-up survey of 209 middle-aged women from either farming or fishing communities in Fukui prefecture, Japan, who participated in the baseline survey in 1990. The following parameters were determined using consistent screening instruments and interview procedures to ensure reliable comparison with the baseline data.A total of 123 women(58.9%) participated in the follow-up survey, with a lower participation rate for the elderly. The major reasons for non-participation besides refusal were death, health care facility admission, and diseases. The participants had a mean age of 70.5 ± 9.3 years and were 22.6 ± 10.5 years post-menopause, on average. The prevalence of osteoporosis in each age group was 22% in 50-59-years-olds, 32% in 60-69-years-olds, 43% in 70-79-years-olds, and 59% in 80-89-years-olds.
… More
Women in the 40-49-years-old age group showed a marked decrease in the lumbar spine BMD that resulted in an approximately 1% decline in BMD from the baseline. The BMD decline was attenuated in the 60-69-years-old age group, but accelerated in 70-79-years-olds, with a nearly 0.6% decline from the baseline.
Grip strength was significantly reduced in women with a negative %BMD compared to those with a positive or maintained %BMD. The degree of BMD decline was lower in the exercise than non-exercise group, although the effect of exercise was less evident in the elderly. In women who were pre-menopausal at the baseline, a negative %BMD was improved by drinking a glass of milk once a day. We evaluated the effect of milk in relation to the duration of the post-menopausal period, and found that single daily milk consumption was also effective for those who were less than 20 years post-menopause in preventing bone mineral loss.Our 15-year follow-up study suggested that body weight, milk consumption, and regular exercise pre-menopause were associated with the prevention of bone mineral loss in middle-aged women Less
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Report
(3 results)
Research Products
(16 results)
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[Journal Article] Intake of fermented soybeans, Naito, is associated with reduced bone loss in postmenopausal women : Japanese population-based osteoporosis (JPOS) study2006
Author(s)
Y, Ikeda, M, Iki, A, Morita, E, Kajita, S, Kagamimori, Y, Kagawa, H, Yoneshima
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Journal Title
J. Nutrition 136(5)
Pages: 1323-1328
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Presentation] A randomized controlled assessment for effectiveness of an evidence-based guideline for osteoporosis and osteoporotic fracture prevention : Design and pre-intervention assessment2007
Author(s)
M, Iki, Y, Nakatani, K, Komatsu, J, Tamaki, E, Kajita
Organizer
ASBMR 29th Annual Meeting, S314(T334)
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Presentation] Relationship between the experience of falls and fracture and the state of social participation in female elderly people living in the local community2006
Author(s)
E, Kajita, Y, Nakatani, I, Matsubara, M, Komatsu, S, Takeuchi, S, Kagamimori
Organizer
IOF world Congress on Osteoporosis9(17, Suppl.205)
Description
「研究成果報告書概要(欧文)」より
Related Report
