Mechanism of photomutagenicity of UV-irradiated food additives and pesticides
Project/Area Number |
18602003
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
食の安全
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Research Institution | Tokyo University of Pharmacy and Life Science |
Principal Investigator |
OHTA Toshihiro Tokyo University of Pharmacy and Life Science, 生命科学部, 教授 (10266893)
|
Project Period (FY) |
2006 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,380,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2006: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
Keywords | 光遺伝毒性 / 変異原性 / 紫外線 / 食品添加物 / 農薬 / マルトール / 複合作用 / チアベンダゾール / 8-OHdG |
Research Abstract |
Maltol are used as a flavor enhancer in breads and cakes. It became mutagenic to bacteria, when the solution was irradiated with UV. Formaldehyde was detected in a crude fraction containing mutagenic photoproduct from UVC-irradiated maltol. However, formaldehyde contributed less than 10% of mutagenicity of the mutagenic fraction.
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Report
(6 results)
Research Products
(21 results)
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[Presentation] Formation of formaldehyde from UVirradiated maltol and ethylmaltol solution2009
Author(s)
Ohta, T., Watanabe-Akanuma, M., Nakajima, D., Inaba, Y., Uchiyama, S.
Organizer
10th International Conference on Environmental Mutagens
Place of Presentation
Firenze, Italy
Related Report
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