| Project/Area Number |
18612002
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
医療における生命倫理
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NAGAMURA Fumitaka The University of Tokyo, Institute of Medical Science, Associate Professor (90282491)
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| Co-Investigator(Kenkyū-buntansha) |
TAHARA Hideaki The University of Tokyo, Institute of Medical Science, Professor (70322071)
OOKI Momoyo Bunkyo University, 人間科学部, Associate Professor (10306269)
NAGAMURA Tokiko The University of Tokyo, Institute of Medical Science, Lecturer (90332585)
SATO Noriharu The University of Tokyo, Institute of Medical Science, Associate Professor (90162461)
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| Project Period (FY) |
2006 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥4,000,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2006: ¥2,700,000 (Direct Cost: ¥2,700,000)
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| Keywords | Conflict of Interest / Translational Research / Informed Consent |
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| Research Abstract |
The results of the study for the patients participated in the Translational Researches performed in the Research Hospital of Institute of Medical Science, University of Tokyo are as follows: almost all of the patients replied that they did not, pay concerns on the source of studies; the answers to the question on patents related to the studies were divided almost, equally to "a little conscious", "almost no conscious" and "no conscious"; the answers to the benefit obtained from the result of studies(i.e., intrinsic Conflict of Interest" were either "very conscious" or "fairly conscious". Interestingly, this result is almost the sonic as the presentation at the Annual Meeting of American Society of Clinical Oncology. And the result was that patients with advanced malignancies participated in Phase T studies, i.e. clinical benefits are usually not expected. paid more concerns on intrinsic Conflict of Interest, not on financial Conflict of Interest., The similarity between the results of our study and that in the US indicates that the concerns of patients in Phase I studies are intrinsic Conflict of Interest. In our study, almost all of patients replies that information on Conflict of Interest was not influenced on their decision mating to participating in the studies. As for the source of money around half of the patients replies that the information on the source of money whether it is from the government or not is necessary. The continual monitoring on the studies was evaluated to be effective to prevent the influences induced by the Conflict of Interest problems. From these results, we should pay more attentions to the intrinsic Conflict of Interest problems.
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