Measurements of cellular microstructure and function using magnetic resonance
| Project/Area Number |
18680037
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SEKINO Masaki The University of Tokyo, 大学院・新領域創成科学研究科, 助教授 (20401036)
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| Project Period (FY) |
2006 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2008: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2007: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2006: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 生物・生体工学 / 磁気共鳴 / 医用画像 / イメージング / 細胞膜 |
|---|
| Research Abstract |
本研究では,生体に含まれる水の拡散の磁気共鳴イメージング(MRI)を通じて,細胞の大きさなどの微視的構造と,それに深く関わる生体組織の導電率や細胞膜透過率などを推定する手法を提案した.シミュレーションや動物のMRI 測定などを通じて,提案手法の有用性を示した.
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Report
(4 results)
Research Products
(87 results)
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[Journal Article] Iron hydroxide nanoparticles coated with poly(ethylene glycol)-poly(aspartic acid) block copolymer as novel magnetic resonance contrast agents for in vivo cancer imaging2007
Author(s)
M. Kumagai, Y. Imai, T. Nakamura, Y. Yamasaki, M. Sekino, S. Ueno, K. Hanaoka, K. Kikuchi, T. Nagano, E. Kaneko, K. Shimokado, and K. Kataoka
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Journal Title
Colloids and Surfaces B: Biointerfaces vol.56
Pages: 174-181
Related Report
Peer Reviewed
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[Journal Article] Retrograde cerebral perfusion with intermittent pressure augmentation provides adequate neuroprotection : diffusion- and perfusion-weighted magnetic resonance imaging study in an experimental canine model2006
Author(s)
M. Kawata, M. Sekino, S. Takamoto, S. Ueno, S. Yamaguchi, K. Kitahori, H. Tsukihara, Y. Suematsu, M. Ono, N. Motomura, T. Morota, and A. Murakami
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Journal Title
The Journal of Thoracic and Cardiovascular Surgery vol.132
Pages: 933-940
Related Report
Peer Reviewed
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[Presentation] Multidirectional RF coils for MRI2009
Author(s)
S. Takemoto, M. Migita, N. Mizuuchi, K. Maruyama, T. Moroi, T. Sueyoshi, M. Sekino, and N. Iriguchi
Organizer
2009 IEEE/ICME International Conference on Complex Medical Engineering
Place of Presentation
Tempe, USA
Year and Date
2009-04-09
Related Report
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