Development of detection technology for electrostatic potential of single biomolecule

• Project/Area Number: 18686059
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Material processing/treatments
• Research Institution: Nagoya University
• Principal Investigator: SAITO Nagahiro Nagoya University, 大学院・工学研究科, 准教授 (00329096)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥30,290,000 (Direct Cost: ¥23,300,000、Indirect Cost: ¥6,990,000); Fiscal Year 2008: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2007: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000); Fiscal Year 2006: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
• Keywords: 表面・界面制御 / 生体分子 / 走査プローブ顕微鏡 / ナノバイオ / 表面電位 / ゼータ電位 / 走査型プローブ顕微鏡

Research Abstract

本研究では、走査型プローブ顕微鏡および光導波路分光法を用いて、異なる化学的特性(はっ水性・親水性)を有する基材表面における生体1分子の吸着挙動の解明を行った。生体分子には、DNAおよびヒト血漿フィブリノーゲン(HPF)をモデルターゲットに用いた。また、ケルビン力顕微鏡およびゼータ電位測定により、これら生体分子の静電ポテンシャルを明らかにした。これらの成果は将来のバイオデバイス作製に向けての基盤技術となる。

Research Products

• [Journal Article] Self-Assembly of Fibrinogen on Binary Organic Monolayer with Microdomains (2009)
  • Author(s): SH. Lee, N. Saito, O. Takai
  • Journal Title: Appl. Surf Sci. (Accepted)
  • Peer Reviewed
• [Journal Article] Highly Reproducible Technique for Three-dimensional Nanostructure Fabrication via Anodiziton Scanning Probe Lithography (2009)
  • Author(s): SH. lee, N. Saito, O. Takai
  • Journal Title: Appl. Sur. Sci. (In press)
  • Peer Reviewed
• [Journal Article] Control of site-selective adsorption reaction on a biomimetic super-hydrophilic /super-hydrophobic micropatterned template (2008)
  • Author(s): T. Ishizaki, H. Sakurai, N. Saito, O. Takai
  • Journal Title: Surf. Coat. Technol. 202 Pages: 5535-5538
  • Peer Reviewed
• [Journal Article] Scanning probe microscopy for the analysis of composite Ti/hydrocarbon plasma polymer thin films (2008)
  • Author(s): A. Choukourov, A. Grinevich, D. Slavinska, H. Biederman, N. Saito, O. Takai
  • Journal Title: Surf. Sci. 602 Pages: 1011-1019
  • Peer Reviewed
• [Journal Article] Effect of Humidity and Solution Age on the Growth of Organosilane Self-Assembled Monolayers (2008)
  • Author(s): S.H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: J. Jpn. Appl. Phys. 47 Pages: 6416-6421
  • NAID: 40016211025
  • Peer Reviewed
• [Journal Article] Surface Characterization on Binary Nano/Micro Domain Composed of Alkyl and Amino-terminated Self-assembled Monolayer (2008)
  • Author(s): S.H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Appl. Surf. Sci. 254 Pages: 7453-7458
  • Peer Reviewed
• [Journal Article] Effect of Reaction Temperature on Growth of Organosilane Self-Assembled Monolayer (2008)
  • Author(s): S.H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: J. Jpn. Appl. Phys. 47 Pages: 6442-6447
  • NAID: 40016211030
• [Journal Article] Comparative study of the molecular aggregation state of alkyl organic monolayers prepared on Si and hydrogen-terminated Si substrates (2008)
  • Author(s): T. Ishizaki, S.H. Lee, N. Saito, O. Takai
  • Journal Title: Nanotehnology 19 Pages: 55601-55607
  • Peer Reviewed
• [Journal Article] Control of Site-selective Adsorption Reaction on a Biomimetic Super-hydrophilic/Super-hydrophobic Micropatterned Template (2008)
  • Author(s): T. Ishizaki, H. Sakurai, N. Saito, O. Takai
  • Journal Title: Surf Coat. Technol. 202 Pages: 5535-5348
  • Peer Reviewed
• [Journal Article] Effects of Humidity and Solution Age on Growth of Organosilane Self-Assembled Monolayers (2008)
  • Author(s): SH. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Jpn. J. Appl. Phys. 47 Pages: 6416-6421
  • NAID: 40016211025
  • Peer Reviewed
• [Journal Article] Effect of Reaction Temperature on Growth of Organosilane Self-Assembled Monolayers (2008)
  • Author(s): SH. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Jpn. J. Appl. Phys 47 Pages: 6442-6447
  • NAID: 40016211030
  • Peer Reviewed
• [Journal Article] Surface Characterization on Binary Nano/Micro-domain Composed of Alkyl-and Amino-terminated Self-Assembled Monolayer (2008)
  • Author(s): Appl. Surf Sci.
  • Journal Title: SH. Lee, T. Ishizaki, N. Saito, O. Takai 254 Pages: 7453-7458
  • Peer Reviewed
• [Journal Article] 自己組織化の構造と機能 (2008)
  • Author(s): 齋藤永宏, 石崎貴裕, 高井治
  • Journal Title: 日本接着学会誌 44 Pages: 363-370
  • NAID: 10024919857
  • Peer Reviewed
• [Journal Article] Surface characterization on binary nano/micro domain composed of alkyl and amino-terminated self-assembled monolayer (2008)
  • Author(s): S. H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Appl. Surf. Sci. (印刷中)
  • Peer Reviewed
• [Journal Article] Application of ultra-water-repellent surface to cell culture (2007)
  • Author(s): K. Ino, A. Ito, Y.Y. Wu, N. Saito, E. Hibino, O. Takai, H. Honda
  • Journal Title: J. Bioscience. Bioengineering 104 Pages: 420-423
  • NAID: 110006402614
  • Peer Reviewed
• [Journal Article] A micropatterned carbohydrate display for tissue engineering by self-assembly of heparin (2007)
  • Author(s): H. Sato, Y. Miura, N. Saito, K. Kobayashi, O. Takai
  • Journal Title: Surf. Sci. 601 Pages: 3871-3875
  • Peer Reviewed
• [Journal Article] Localized surface plasmon resonance of silicon compounds adsorbed on silver nanoparticles (2007)
  • Author(s): M.A. Bratescu, N. Saito, H. Mori, O. Takai
  • Journal Title: Surf. Sci. 601 Pages: 3886-3891
  • Peer Reviewed
• [Journal Article] Probing into Adsorption Behavior of Human Plasma Fibrinogen on Self-Assembled Monolayers with Different Chemical Properties by Scanning Probe Microscopy (2007)
  • Author(s): T. Ishizaki, N. Saito, Y. Sato, O. Takai
  • Journal Title: Surf. Sci. 601 Pages: 3861-3865
  • Peer Reviewed
• [Journal Article] SPM analysis of fibrinogen adsorption on solid surfaces (2007)
  • Author(s): A. Choukourov, A. Grinevich, N. Saito, O. Takai
  • Journal Title: Surf. Sci. 601 Pages: 3948-3951
  • Peer Reviewed
• [Journal Article] Electrochemical soft lithography of an 1,7-octadiene monolayer covalently linked to hydrogen-terminated silicon using scanning probe microscopy (2007)
  • Author(s): S.H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Surf. Sci. 601 Pages: 4206-4211
  • Peer Reviewed
• [Journal Article] Local generation of carboxyl groups on an organic monolayer through chemical conversion using scanning probe anodization (2007)
  • Author(s): S.H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Journal Title: Mater. Sci. Eng., C 27 Pages: 1241-1246
  • Peer Reviewed
• [Journal Article] Patterned hydrophobic-hydrophilic templates made from microwave-plasma enhanced chemical vapor deposited thin films (2007)
  • Author(s): Y.Y. Wu, M. Kouno, N. Saito, F.A. Nae, Y. Inoue, O. Takai
  • Journal Title: Thin Solid Films 515 Pages: 4203-4208
  • Peer Reviewed
• [Journal Article] A micropatterned multifunctional carbohydrate display by an orthogonal self-assembling strategy (2007)
  • Author(s): H. Sato, Y. Miura, N. Saito, K. Kobayashi, O. Takai
  • Journal Title: Biomacromolecules 8 Pages: 753-756
  • Peer Reviewed
• [Journal Article] The Importance of Precursor Molecules Symmetry in the Formation of Self-assembled Monolayers (2007)
  • Author(s): S.H. Lee, N. Saito, O. Takai
  • Journal Title: Jpn. J. Appl. Phys., Part 1 46 Pages: 1118-1123
  • NAID: 10018867451
• [Journal Article] Electrochemical soft lithography of an 1,7-octadiene monolayer covalently linked to hydrogen-terminated silicon using scanning probe microscope (2007)
  • Author(s): S.H.Lee, T.Ishizaki, N.Saito, O.Takai
  • Journal Title: Surf. Sci. (印刷中)
• [Journal Article] Probing into adsorption behavior of human plasma fibrinogen on self-assembled monolayers with different chemical properties by scanning probe microscopy (2007)
  • Author(s): T.Ishizaki, N.Saito, O.Takai
  • Journal Title: Surf. Sci. (印刷中)
• [Journal Article] Local generation of carboxyl groups on an organic monolayer through chemical conversion using scanning probe anodization (2007)
  • Author(s): S.H.Lee, T.Ishizaki, N.Saito, O.Takai
  • Journal Title: Mater. Sci. Engineer. C. (印刷中)
• [Journal Article] SPM analysis of fibrinogen adsorption on solid surfaces (2007)
  • Author(s): A.Choukourov, N.Saito, O.Takai
  • Journal Title: Surf. Sci. (印刷中)
• [Journal Article] A micropatterned carbohydrate display for tissue engineering by self-assembly of heparin (2007)
  • Author(s): H.Sato, Y.Miura, N.Saito, K.Kobayashi, O.Takai
  • Journal Title: Surf. Sci. (印刷中)
• [Journal Article] Visualization of human plasma fibrinogen adsorbed on highly oriented pyrolytic graphite by scanning probe microscopy (2006)
  • Author(s): R. Ohta, N. Saito, T. Ishizaki, O. Takai
  • Journal Title: Surf. Sci. 600 Pages: 1674-1678
  • Peer Reviewed
• [Journal Article] Treatment of Immobilized Collagen on Poly(tetrafluoroethylene) Nanoporous Membrane with Plasma (2006)
  • Author(s): M.A. Bratescu, N. Saito, O. Takai
  • Journal Title: Jpn. J. Appl. Phys. 45 Pages: 8352-8357
  • NAID: 10018339805
  • Peer Reviewed
• [Journal Article] Carbohydrate microarrays by click chemistry (2006)
  • Author(s): H. Sato, Y. Miura, T. Yamauchi, N. Saito, K. Kobayashi, O. Takai
  • Journal Title: Trans. Mater. Research. Soc. 31 Pages: 659-703
  • Peer Reviewed
• [Journal Article] Study of alkyl organic monolayers with different alkyl chain lengths directly attached to silicon (2006)
  • Author(s): T. Ishizaki, N. Saito, S.H. Lee, K. Ishida, O. Takai
  • Journal Title: Langmuir 22 Pages: 9962-9966
  • Peer Reviewed
• [Journal Article] Visualization of human plasma fibrinogen adsorbed on highly oriented pyrolytic graphite by scanning probe microscopy (2006)
  • Author(s): R.Ohta, N.Saito, T.Ishizaki, O.Takai
  • Journal Title: Surf. Sci. 600 Pages: 1674-1674
• [Presentation] 超はっ水/PEGマイクロテンプレートを用いた微生物の位置選択的固定化 (2009)
  • Author(s): 樋口晶生, 宮原康弘, 齋藤永宏, 高井 治
  • Organizer: 日本金属学会2009年春期(第114回)講演大会
  • Place of Presentation: 東京,日本
  • Year and Date: 2009-03-26
• [Presentation] 疎水性及び親水性二元系SAMの濡れ性の評価 (2009)
  • Author(s): 鈴木和也, 李 先炯, 齋藤永宏, 高井 治
  • Organizer: 日本金属学会2009年春期(第114回)講演大会
  • Place of Presentation: 東京,日本
  • Year and Date: 2009-03-26
• [Presentation] Adsorption of protein on polyelectrolyte brush surface (2009)
  • Author(s): A. Higuchil, H. Tatematsu, T. Fujima, N. Saito, O. Takai
  • Organizer: Spring 2009 National Meeting & Exposition
  • Place of Presentation: Salt Lake City, U.S.A.
  • Year and Date: 2009-03-23
• [Presentation] Adsorption of Protein on Polyelectrolyte Brush Surface (2009)
  • Author(s): A. Higuchil, H. Tateniatsu, T. Fujima, N. Saito, O. Takai
  • Organizer: Spring 2009 National Meeting & Exposition
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2009-03-23
• [Presentation] Chemical dynamics of protein adsorption and desorption on regulated surfaces in aqueous solutions (2009)
  • Author(s): N. Saito, J. Hieda, O. Takai
  • Organizer: Spring 2009 National Meeting & Exposition
  • Place of Presentation: Salt Lake City, U.S.A.
  • Year and Date: 2009-03-22
• [Presentation] Chemical Dynamics of Protein Adsorption and Desorption on Regulated Surfaces in Aqueous Solutions (2009)
  • Author(s): IN. Saito, J. Hieda, O. Takai
  • Organizer: Spring 2009 National Meeting & Exposition
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2009-03-22
• [Presentation] Added Salt Effect on a Fibrinogen Immobilization Kinetics at a Polelectrolyte Brush (2009)
  • Author(s): T. Fujima, M. Matsuno, M. Bratescu, N. Saito, O. Takai
  • Organizer: Ninth International Symposium on Biomimetic Materials Processing(BMMP-9)
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2009-01-21
• [Presentation] Added Salt Effect on a Fibrinogen Immobilization Kinetics at a Polvelectrolvte Brush (2009)
  • Author(s): T. Fujima, M. Matsuno, M. Bratescu, N. Saito, O. Takai
  • Organizer: Ninth International Symposium on Biomimetic Materials Processing (BMMP-9)
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2009-01-21
• [Presentation] Added Salt Effect on a Fibrinogen Adsorption Kinetics at a Planer Strong Polyelectrolyte Brush (2008)
  • Author(s): T. Fujima, M. Matsuno, M. A. Bratescu, N. Saito, O. Takai
  • Organizer: IUMRS-ICA 2008
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-12-11
• [Presentation] Evaluation of Polyelectrolyte Brush Surface (2008)
  • Author(s): H. Tatematsu, T. Fujima, N. Saito, O. Takai
  • Organizer: IUMRS-ICA 2008
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-12-11
• [Presentation] The Influence of Physicochemical Properties to Bacterial Adsorption to Material Surfaces (2008)
  • Author(s): Y. Miyahara, N. Saito, O. Takai
  • Organizer: IUMRS-ICA 2008
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-12-10
• [Presentation] UV-ATR Polarization Spectroscopy of Self-Assembled Coumarin Monolayer (2008)
  • Author(s): M.A. Bratescu, D.B. Allred, N. Saito, M, Sarikaya, O. Takai
  • Organizer: IUMRS-ICA 2008
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-12-10
• [Presentation] Study of Protein Adsorption onto a Polymer Film by in-situ UV Attenuated Total Reflectance Spectroscopy (2008)
  • Author(s): M.A. Bratescu, S. Fujita, N. Saito, O. Takai
  • Organizer: MRS fall meeting 2008
  • Place of Presentation: Boston, USA
  • Year and Date: 2008-12-01
• [Presentation] Kinetic Study of Protein Adsorption on Polyelectrolyte Brush Surface (2008)
  • Author(s): H. Tatematsu, T. Fujima, N. Saito, O. Takai
  • Organizer: AVS 55th International Symposium and Exhibition
  • Place of Presentation: Boston, USA
  • Year and Date: 2008-10-21
• [Presentation] Fabrication of Micro-Templates for the Control of Bacterial Immobilization (2008)
  • Author(s): Y. Miyahara, N. Saito, O. Takai
  • Organizer: AVS 55th International Symposium and Exhibition
  • Place of Presentation: Boston, USA
  • Year and Date: 2008-10-21
• [Presentation] Kinetic Study of Protein Adsorption on Polyelectrolyte Brush Surface (2008)
  • Author(s): H. Tatematsu, T. Fujima, N. Saito, O. Takai
  • Organizer: AVS 55 th International Symposium and Exhibition
  • Place of Presentation: Boston, USA
  • Year and Date: 2008-10-21
• [Presentation] 微生物付着制御のためのマイクロテンプレートの作製 (2008)
  • Author(s): 稗田純子, 宮原康弘, 齋藤永宏, 高井 治
  • Organizer: 第57回高分子討論会
  • Place of Presentation: 大阪市立大学,日本
  • Year and Date: 2008-09-25
• [Presentation] 微生物吸着挙動に及ぼす物理化学的表面特性の影響 (2008)
  • Author(s): 宮原康弘, 齋藤永宏, 高井 治
  • Organizer: 第118回講演大会(主催 : 表面技術協会)
  • Place of Presentation: 近畿大学,日本
  • Year and Date: 2008-09-02
• [Presentation] In-situ Study of Bacterial S-layer Protein Binding Process with Noble Metal Surface (2008)
  • Author(s): M. A. Bratescu, D.B. Allred, N. Saito, M. Sarikaya, O. Takai
  • Organizer: Interfinish 2008
  • Place of Presentation: 釜山,韓国
  • Year and Date: 2008-06-17
• [Presentation] Adhesion Control of Bacteria with Micropatterned Super-Hydrophobic/Super-Hydrophilic and Super-Hydrophobic/Poly(Ethelene Glycol) Surfaces (2008)
  • Author(s): Y. Miyahara, T. Ishizaki, N. Saito, O. Takai
  • Organizer: Interfinish 2008,
  • Place of Presentation: 釜山,韓国
  • Year and Date: 2008-06-17
• [Presentation] 高分子電解質ブラシ上へのタンパク質捕捉キネティクスの添加塩濃度依存性価 (2008)
  • Author(s): 藤間卓也, 松野正幸, 齋藤永宏, 高井 治
  • Organizer: 2008年春季第55回応用物理学関係連合講演会
  • Place of Presentation: 東京,日本
  • Year and Date: 2008-03-29
• [Presentation] 固体表面形状と細菌付着の関係 (2008)
  • Author(s): 宮原康弘, 石崎貴裕, 齋藤永宏, 高井 治
  • Organizer: 2008年春季第55回応用物理学関係連合講演会
  • Place of Presentation: 東京,日本
  • Year and Date: 2008-03-29
• [Presentation] 機能性有機分子膜上でのヒト血漿フィブリノーゲン吸着挙動の解析と制御 (2008)
  • Author(s): 松野正幸, 藤間卓也, Maria A. Bratescu, 石崎貴裕, 齋藤永宏, 高井 治
  • Organizer: 表面技術協会第117回講演大会
  • Place of Presentation: 東京,日本
  • Year and Date: 2008-03-12
• [Presentation] In-situ Study of the Bacterial S-layer Protein Adsorption by Attenuated Total Reflectance Spectroscopy (2008)
  • Author(s): M.A. Bratescu, D.B. Allred, N.Saito, O. Takai
  • Organizer: Eighth International Symposium on Biomimetic Materials Processing(BMMP-8)
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-01-23
• [Presentation] はっ水および親水性表面上でのヒト血漿フィブリノゲン・ヘパリンの吸着挙動 (2007)
  • Author(s): 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-09
• [Presentation] Study of bacterial S-layer protein adsorption by attenuated total reflection spectroscopyh (2007)
  • Author(s): M. A. Bratescu, D. B. Allred, N. Saito, O. Takai
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-09
• [Presentation] 溶液中における自己組織化単分子膜を介して電子移動を伴うヒト血漿フィブリノーゲンの分子構造 (2007)
  • Author(s): 松野正幸, M. A. Bratescu, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-09
• [Presentation] 超はつ水腹構造に起因する細菌の付着 (2007)
  • Author(s): 宮原康弘, 石崎貴裕, 斎藤永宏, 高井治
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-08
• [Presentation] 表面修飾によるフィブリノーゲンーアルブミン競争吸着への影響 (2007)
  • Author(s): 佐藤有紀, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-08
• [Presentation] 自己組織化単分子膜へのヒト血漿フィブリノーゲン吸着挙動 (2007)
  • Author(s): 松野正幸, M. A. Bratescu, 石崎貴裕, 斎藤永宏, 高井治
  • Organizer: 第21回「ナノテク部会」研究会
  • Place of Presentation: 長野
  • Year and Date: 2007-11-17
• [Presentation] Adhesion and Growth of Fibroblast Cell on a Micropatterned Super-Hydrophobic/Super-Hydrophilic Surface (2007)
  • Author(s): Y. Miyahara, T. Ishizaki, N. Saito, O. Takai
  • Organizer: 27th International Symposium on Dry Process
  • Place of Presentation: 東京
  • Year and Date: 2007-11-13
• [Presentation] Adsorption of an S-Layer Bacterial Protein by Total Internal Reflection UV Absorption Spectroscopy (2007)
  • Author(s): M. A. Bretescu, D. B. Allred, N. Saito, M. Sarikaya, O. Takai
  • Organizer: AVS 54th International Symposium & Exhibition
  • Place of Presentation: Seattle, USA
  • Year and Date: 2007-10-16
• [Presentation] In situ Analysis of Fibrinogen on Self-Assembled Monolayers by Evanescent Optical Spectroscopy (2007)
  • Author(s): M. Matsuno, T. Ishizaki, N. Saito, O. Takai
  • Organizer: AVS 54th International Symposium & Exhibition
  • Place of Presentation: Seattle, USA
  • Year and Date: 2007-10-16
• [Presentation] マイクロドメイン構造を有する2元有機単分子膜上でのフィブリノーゲン自己組織化 (2007)
  • Author(s): 李先炳, 石崎貴裕, 斎藤永宏, 高井治
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-09-21
• [Presentation] ポリエチレングリコール単分子膜上フィブリノーゲンの動的挙動 (2007)
  • Author(s): 松野正幸, M. A. Bratescu, 石崎貴裕, 斎藤永宏, 高井治
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-09-19
• [Presentation] プラズマナノテクノロジーを用いたバイオ界面の構築 (2007)
  • Author(s): 齋藤永宏, 高井治
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-09-19
• [Presentation] 血中タンパク質フィブリノーゲンアルブミンの競争吸着に関する速度論的研究 (2007)
  • Author(s): 佐藤有紀, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 表面技術協会 第116回講演大会
  • Place of Presentation: 長崎
  • Year and Date: 2007-09-18
• [Presentation] Chemical kinetics and Dynamics of Fibrinogen and Albumin Adsorption on Materials (2007)
  • Author(s): Y. Sato, T. Ishizaki, N. Saito, O. Takai
  • Organizer: The Doyama Symposium on Advanced Materials
  • Place of Presentation: 東京
  • Year and Date: 2007-09-06
• [Presentation] Counterion Immobilization in a Strong Polyelectrolyte Brush by ZetaPotential (2007)
  • Author(s): T. Fujima, T. Okano, N. Saito, O. Takai
  • Organizer: The Doyama Symposium on Advanced Materials
  • Place of Presentation: 東京
  • Year and Date: 2007-09-06
• [Presentation] Micro-Patterned surface potential of allylamine plasma polymers tuned bynanoprobe chemistry (2007)
  • Author(s): A. Choukourov, A. Grinevich, M. Drabik, D. Slavinska, H. Biederman, N. Saito, O. Takai
  • Organizer: 18th International Symposium on Plasma Chemistry
  • Place of Presentation: 京都
  • Year and Date: 2007-08-27
• [Presentation] Bioactivity control 0f material surface used by Surface-wave plasma(SWP) (2007)
  • Author(s): S. Fujita, T. Ishizaki, N. Saito, O. Takai
  • Organizer: 18th International Symposium on Plasma Chemistry
  • Place of Presentation: 京都
  • Year and Date: 2007-08-27
• [Presentation] Electrochemical Scanning Probe Lithography toward Surface Potential Memory (2007)
  • Author(s): S. H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Organizer: International Conference on Electronics Packaging
  • Place of Presentation: 東京
  • Year and Date: 2007-04-19
• [Presentation] 固体表面形状と細菌付着の関係 (2007)
  • Author(s): 宮原康弘, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 2008年春季第55回応用物理学関係連合講演会
  • Place of Presentation: 千葉
  • Year and Date: 2007-03-29
• [Presentation] 高分子電解質ブラシ上へのタンパク質捕捉キネティクスの添加塩濃度依存性 (2007)
  • Author(s): 藤間卓也, 松野正幸, 齋藤永宏, 高井治
  • Organizer: 2008年春季第55回応用物理学関係連合講演会
  • Place of Presentation: 千葉
  • Year and Date: 2007-03-29
• [Presentation] 表面波プラズマ開始グラフト重合によるPET表面の生体活性制御 (2007)
  • Author(s): 藤田翔兵, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 2008年春季第55回応用物理学関係連合講演会
  • Place of Presentation: 千葉
  • Year and Date: 2007-03-28
• [Presentation] 機能性有機分子膜上でのヒト血漿フィブリノーゲン吸着挙動の解析と制御 (2007)
  • Author(s): 松野正幸, 藤間卓也, M. A. Bratescu, 石崎貴裕, 齋藤永宏, 高井治
  • Organizer: 表面技術協会 第117回講演大会
  • Place of Presentation: 千葉
  • Year and Date: 2007-03-12
• [Presentation] In-situ Study of the Bacterial S-layer Protein Adsorption by Attenuated Total Reflectance Spectroscopy (2007)
  • Author(s): M. A. Bratescu, D. B. Allred, N. Saito, O. Takai
  • Organizer: Eighth International Symposium on Biomimetic Materials Processing (BMMP-8)
  • Place of Presentation: 名古屋
  • Year and Date: 2007-01-23
• [Presentation] Control of the Wetting and Electrokinetic Properties on Binary SAM Surface (2007)
  • Author(s): S. H. Lee, T. Ishizaki, N. Saito, O. Takai
  • Organizer: Eighth International Symposium on Biomimetic Materials Processing (BMMP-8)
  • Place of Presentation: 名古屋
  • Year and Date: 2007-01-23
• [Presentation] XAFS Analysis of Ag in the Glaze of Anti-bacterial Ceramics (2007)
  • Author(s): K. Kato, N. Isu, S. Yamazaki, A. Nakahira, C. Numako, N. Saito, O. Takai
  • Organizer: Eighth International Symposium on Biomimetic Materials Processing (BMMP-8)
  • Place of Presentation: 名古屋
  • Year and Date: 2007-01-23
• [Presentation] Fibrinogen Immobilization Kinetics on Sodium Polystyrene Sulfonate Brushby Time-Resolved UV Absorption Spectroscopy (2007)
  • Author(s): T. Fujima, M. Matsuno, N. Saito, O. Takai
  • Organizer: Eighth International Symposium on Biomimetic Materials Processing (BMMP-8)
  • Place of Presentation: 名古屋
  • Year and Date: 2007-01-22
• [Presentation] SOWA分光法によるポリスチレンスルホン酸Naブラシ上へのタンパク質捕捉キネティクス (2007)
  • Author(s): 藤間卓也, 松野正幸, 齋藤永宏, 高井治
  • Organizer: 非平衡ソフトマター物理学の創成
  • Place of Presentation: 名古屋
  • Year and Date: 2007-01-07
• [Book] I-1.6 自己組織化とその利用, I-4.6 化学特性, 薄膜ハンドブック (2008)
  • Author(s): 齋藤永宏, 藤間卓也, 高井治
  • Publisher: オーム社
• [Book] 撥水・撥油の技術と材料 (2008)
  • Author(s): 石崎貴裕, 齊藤永宏, 高井治
  • Total Pages: 311
  • Publisher: 株式会社シーエムシー出版
• [Book] 自己組織化単分子膜を利用した分子メモリの作製, 自然に学ぶ材料プロセッシング (2007)
  • Author(s): 齋藤永宏, 石崎貴裕
  • Publisher: 三協出版
• [Book] 超はっ水性および超親水性表面を用いた新しい細胞培養技術 (2007)
  • Author(s): 高井 治, 石崎貴裕, 齋藤永宏
  • Publisher: エヌ・ティー・エス
• [Book] 自然に学ぶ材料プロセッシング (2007)
  • Author(s): 石崎貴裕, 齋藤永宏, 高井治
  • Total Pages: 370
  • Publisher: 三協出版
• [Book] バイオプロセスハンドブック (2007)
  • Author(s): 高井治, 石崎貴裕, 齋藤永宏
  • Total Pages: 724
  • Publisher: NTS
• [Remarks]
  • URL: http://eco-t.esi.nagoya-u.ac.jp/~takai/
• [Patent(Industrial Property Rights)] 自己組織化単分子膜の作製方法とその利用 (2008)
  • Inventor(s): 齋藤 永宏, 石崎 貴裕, 高井 治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Acquisition Date: 2008-01-18
• [Patent(Industrial Property Rights)] 自己組織化単分子膜の作製方法とその利用 (2008)
  • Inventor(s): 齋藤永宏, 石崎貴裕, 高井治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Acquisition Date: 2008-01-08
• [Patent(Industrial Property Rights)] マイクロパターンの形成方法, マイクロパターン, マイクロパターン転写形成用モールドの作製方法, 及びマイクロパターン転写形成モールド (2007)
  • Inventor(s): 杉村博之, 齋藤永宏, 高井治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Acquisition Date: 2007-06-12
• [Patent(Industrial Property Rights)] 自己組織化単分子膜の作製法とその利用 (2006)
  • Inventor(s): 齋藤 永宏, 石崎 貴裕, 高井 治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Filing Date: 2006-04-15
  • Overseas
• [Patent(Industrial Property Rights)] 自己組織化単分子膜の作製法 (2006)
  • Inventor(s): 齋藤 永宏, 石崎 貴裕, 高井 治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Filing Date: 2006-08-10
• [Patent(Industrial Property Rights)] 自己組織化単分子膜作製装置とその利用 (2006)
  • Inventor(s): 齋藤 永宏, 石崎 貴裕, 高井 治
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Filing Date: 2006-12-27
• [Patent(Industrial Property Rights)] 自己組織化単分子膜の作製法とその利用 (2006)
  • Inventor(s): 齋藤永宏, 石崎貴裕, 高井治
  • Filing Date: 2006-04-15