Gene transfer to sperm and testis : future prospects of gene therapy for male infertility.
| Project/Area Number |
18689039
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Nagoya City University |
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Principal Investigator |
KOJIMA Yoshiyuki Nagoya City University, 大学院・医学研究科, 講師 (60305539)
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| Project Period (FY) |
2006 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2007: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2006: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | 男子不妊症 / 精巣 / 遺伝子導入 / 転写因子 / 造精機能 / アデノウイルスベクター / DAX-1 |
|---|
| Research Abstract |
アデノウイルスベクターは男子不妊症治療を前提とした精巣内遺伝子導入法としては最も優れた遺伝子導入法であることを明らかにした。DAX-1およびAd4BP/SF-1をアデノウイルスベクターに組み込み、精巣体細胞への遺伝子導入を試みた。
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Report
(4 results)
Research Products
(48 results)
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[Journal Article]2008
Author(s)
Kamisawa H, Kojima Y, Hayashi Y, Imura M, Mizuno K, Kohri K.Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism.
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Journal Title
Int Urol Nephrol 40
Pages: 977-81
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Peer Reviewed
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[Book] Andrology for clinician2006
Author(s)
Kojima Y., Sasaki S, Kohri K.
Publisher
Therapeutic options: Current research and future prospects for gene therapy in andrology. Hargreave T, Comhaire F, Schill W-B (eds) In
Related Report
