Study on non-parametric statistical inference for repeated measurements

• Project/Area Number: 18700280
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Statistical science
• Research Institution: Kurume University
• Principal Investigator: HATTORI Satoshi Kurume University, バイオ統計センター, 准教授 (50425154)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,400,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥1,000,000 (Direct Cost: ¥1,000,000); Fiscal Year 2006: ¥1,100,000 (Direct Cost: ¥1,100,000)
• Keywords: 医薬生物統計 / 累積残差 / 影響度分析 / 欠測データ / 重み付き推定方程式 / セミパラメトリックモデル / 局所影響度分析 / リサンプリング

Research Abstract

医学研究においては、関心のある評価項目が経時的に繰り返し測定され、評価されることがしばしば行われる。このような繰り返し測定データの解析に対し、最近生存時間の手法が効果的に導入されたが、本研究ではその方法の適切性を評価するための方法を開発した。理論的あるいは計算機シミュレーションにより、提案法は実際の医学研究に有意義な方法であることが見出された。

Research Products

• [Journal Article] Approximate subject-deletion influence diagnostics for Inverse Probability of Censoring Weighted (IPCW) method (2009)
  • Author(s): Hattori, S. and Kato, M.
  • Journal Title: Statistics and Probability Letters (in press)
  • Peer Reviewed
• [Journal Article] 生存時間解析におけるセミパラメトリック推測とその周辺 (2009)
  • Author(s): 服部聡
  • Journal Title: 統計数理 (in press)
  • NAID: 120006018981
  • Peer Reviewed
• [Journal Article] A Change-point Regression Approach for Efficacy Evaluation of Dietary] Supplements (2009)
  • Author(s): Hayamizu, K., Yamashita, N., Hattori, S., and Kakuma, T.
  • Journal Title: Journal of Clinical Biochemistry and Nutrition 44 Pages: 285-290
  • NAID: 130004466553
  • Peer Reviewed
• [Journal Article] Regression diagnostics of the semiparametric proportional rate model for irregularly-spaced repeated measurements (2009)
  • Author(s): Hattori, S.
  • Journal Title: Communications in Statistics, Theory and Methods 38 Pages: 542-559
  • Peer Reviewed
• [Journal Article] Regression diagnostics of the semiparametric proportional rate model for irregularly-spaced repeated measurements (2009)
  • Author(s): Hattori, S
  • Journal Title: Communications in Statistics, Theory and Methods 38 Pages: 542-559
  • Peer Reviewed
• [Journal Article] 生存時間解析におけるセミパラメトリック推測とその周辺 (2009)
  • Author(s): Hattori, S
  • Journal Title: 統計数理 (印刷中)
  • NAID: 120006018981
  • Peer Reviewed
• [Journal Article] Checking the linear transformation model for clustered failure time observations (2008)
  • Author(s): Hattori, S.
  • Journal Title: Lifetime Data Analysis 14 Pages: 253-266
  • Peer Reviewed
• [Journal Article] Expression of HER2 and Estrogen Receptor Alpha Depends upon Nuclear Localization of Y-box Binding Protein-1 in Human Breast Cancers (2008)
  • Author(s): Fujii, T.
  • Journal Title: Cancer Research 68 Pages: 1504-1512
  • Peer Reviewed
• [Journal Article] Checking linear transformation model for clustered failure time observations. (2008)
  • Author(s): Hattori, s.
  • Journal Title: Lifetime Data Analysis (印刷中)
  • Peer Reviewed
• [Journal Article] Some properties of misspecified additive hazards models (2006)
  • Author(s): Hattori,S.
  • Journal Title: Statistics and Probability Letters 76 Pages: 1641-46
  • Peer Reviewed
• [Journal Article] A note on misspecified transformation models (2006)
  • Author(s): Hattori,S.
  • Journal Title: Bulletin of Informatics and Cybernetics 38 Pages: 51-58
  • NAID: 120001014497
  • Peer Reviewed
• [Journal Article] PtC ADJUSTMENT OF BASELINE COVARIATESに関して (2006)
  • Author(s): 服部 聡
  • Journal Title: Japanese Journal of Biometrics 27 Pages: 22-25
• [Journal Article] Some properties of misspecified additive hazards models. (2006)
  • Author(s): Satoshi Hattori
  • Journal Title: Statistics and Probability Letters 76 Pages: 1641-1646
• [Journal Article] A note on misspecified transformation models. (2006)
  • Author(s): Satoshi Hattori
  • Journal Title: Bulletin of Informatics and Cybernetics 38 Pages: 51-58
  • NAID: 120001014497
• [Presentation] Approximate subject-deletion influence diagnostics for Inverse Probability of Censoring Weighted (IPCW) methods (2008)
  • Author(s): Kato, M., and Hattori, S.
  • Organizer: IASC2008
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2008-12-07
• [Presentation] Comparing randomized groups based on accelerated failure time model (2008)
  • Author(s): Hattori, S.
  • Organizer: IASC2008
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2008-12-06
• [Presentation] 重み付き推定方程式に対する局所影響度分析 (2008)
  • Author(s): 加藤舞,服部聡
  • Organizer: 統計関連学会連合大会
  • Year and Date: 2008-09-09
• [Presentation] 重み付き推定方程式に対する局所影響度分析 (2008)
  • Author(s): 加藤舞
  • Organizer: 統計関連学会連合大会
  • Place of Presentation: 慶應義塾大学
  • Year and Date: 2008-09-09
• [Presentation] Approximate subject-deletion influence diagnostics for Inverse Probability of Censoring Weighted (IPCW) methods (2008)
  • Author(s): Hattori, S. and Kato, M.
  • Organizer: International Biometric Conference
  • Place of Presentation: Dublin, Ireland
  • Year and Date: 2008-07-16
• [Presentation] Approximate subject-deletion influence diagnostics for Inverse Probability of Censoring Weighted (IPCW) methods. (2008)
  • Author(s): Hattori, S.
  • Organizer: The 2nd International Kurume Symposium on Biostatistics: Analysis of Longitudinal Data and Related Topics
  • Place of Presentation: 九州大学百年記念講堂
  • Year and Date: 2008-02-26
• [Presentation] Approximate subject-deletion influence diagnostics for Inverse Probability of Censoring Weighted (IPCW) methods (2008)
  • Author(s): Hattori, S. and Kato, M.
  • Organizer: The 2nd International Kurume Symposium on Biostatistics: Analysis of Longitudinal Data and Related Topics
  • Place of Presentation: 九州大学百年記念講堂
• [Presentation] Mantel-Haenszel estimator for irregular sparse K2XJ(J>2) tables (2007)
  • Author(s): Hattori, S. and Yanagawa, T.
  • Organizer: East-Asia Regional Biometrics Conference 2007
  • Place of Presentation: 東京大学弥生講堂(Invited Talk)
  • Year and Date: 2007-12-06
• [Presentation] Mantel-Haenszel estimator for irregular sparse K 2XJ (J>2) tables. (2007)
  • Author(s): Hattori, S.
  • Organizer: East-Asia Regional Biometrics Conference 2007
  • Place of Presentation: 東京大学弥生講堂
  • Year and Date: 2007-12-06
• [Presentation] Regression diagnosis of a semiparametric marginal model for repeated measurements (2007)
  • Author(s): Hattori, S.
  • Organizer: Workshop on Stochastic Analysis and Statistics
  • Place of Presentation: 東京大学数理学研究科
  • Year and Date: 2007-11-29
• [Presentation] Regression diagnosis of a semiparametric marginal model for repeated measurements. (2007)
  • Author(s): Hattori, S.
  • Organizer: Workshop on Stochastic Analysis and Statistics
  • Place of Presentation: 東京大学数理学研究科
  • Year and Date: 2007-11-29
• [Presentation] セミパラメトリック周辺モデルに対する回帰診断 (2007)
  • Author(s): 服部聡
  • Organizer: 2007年度統計関連学会連合大会
  • Place of Presentation: 神戸大学
  • Year and Date: 2007-09-07
• [Presentation] セミパラメトリック周辺モデルに対する回帰診断. (2007)
  • Author(s): 服部 聡
  • Organizer: 2007年度統計関連学会連合大会
  • Place of Presentation: 神戸大学
  • Year and Date: 2007-09-07
• [Presentation] Modified projection-method Mantel-Haenszel estimators for sparse K 2XJ(J>2) tables (2007)
  • Author(s): Hattori, S.
  • Organizer: The 56th Session of ISI
  • Place of Presentation: Lisbon, Portugal
  • Year and Date: 2007-08-25
• [Presentation] Semiparametric Inference for Illegularly-spaced repeated measurements (2007)
  • Author(s): Hattori, S.
  • Organizer: The 2007Taipei International Statistical Symposium and ICSA International Conference
  • Place of Presentation: Academia Sinica (Invited Talk)
  • Year and Date: 2007-06-25
• [Presentation] Semiparametric Inference for Irregularly-spaced repeated measurements. (2007)
  • Author(s): Hattori, S.
  • Organizer: The 2007 Taipei International Statistical Symposium and ICSA International Conference
  • Place of Presentation: Academia Sinica
  • Year and Date: 2007-06-25
• [Presentation] Modified projection-method Mantel-Haenszel estimators for sparse K2XJ(J>2) tables (2007)
  • Author(s): Hattori, S. and Yanagawa, T.
  • Organizer: ISI2007
  • Place of Presentation: Lisbon, Portugal
• [Presentation] Analysis of gap times with nonproportional hazards models (2006)
  • Author(s): 服部聡
  • Organizer: 2006年度統計関連学会連合大会
  • Place of Presentation: 東北大学
  • Year and Date: 2006-09-07
• [Presentation] Counting process approach to longitudinal data analysis (2006)
  • Author(s): 服部聡
  • Organizer: 2006年度統計関連学会連合大会
  • Place of Presentation: 東北大学(招待講演)
  • Year and Date: 2006-09-06
• [Presentation] Mantel-Haenszel projection method estimators for sparse K2xJ tables(poster presentation) (2006)
  • Author(s): Hattori, S. and Yanagawa, T.
  • Organizer: XXIIIrd Iternational Biometric Conference
  • Place of Presentation: Montreal,Canada