Spike-field correlation analysis of mnemonic information from area 36 to area TE of macaque inferotemporal cortex

• Project/Area Number: 18700309
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Neuroscience in general
• Research Institution: The University of Tokyo
• Principal Investigator: TAKEDA Masaki The University of Tokyo, 大学院・医学系研究科, 助教 (00418659)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,710,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2007: ¥900,000 (Direct Cost: ¥900,000); Fiscal Year 2006: ¥1,900,000 (Direct Cost: ¥1,900,000)
• Keywords: 認知神経科学 / 脳・神経 / 大脳生理学 / 視覚記憶 / 神経科学 / 視覚状態

Research Abstract

視覚記憶課題遂行中のサル下部側頭葉における単一ユニット活動と局所フィールド電位を記録し、周波数領域の相関解析を行ったところ、これらの神経活動がコヒーレントに活動していた。課題関連部位をin vivoで同定するために、高磁場MRIを用いた記録部位同定法を開発した。電極ファントムを作成し高精度に記録部位を同定する撮像条件を調べた。この条件下でサル大脳皮質内の記録部位を同定すると、1ボクセル以下の誤差で同定できた。

Research Products

• [Journal Article] Functional characterization of area 35 in the macaque perirhinal cortex during a pair association task. Program No. 219.1. (2008)
  • Author(s): Fujimichi, R., Takeda, M., Naya, Y., Koyano, K.W., Takeuchi, D., Miyashita, Y.
  • Journal Title: 2008 Neuroscience Meeting Planner Washington, DC: Society for Neuroscience
  • Peer Reviewed
• [Journal Article] Electrolysis of an elgiloy electrode can create MRI-visible metal deposit marks at recording sites. Program No. 885.2. (2008)
  • Author(s): Koyano, K.W., Machino., A, Takeda, M., Fujimichi, R., Ohashi, Y., Matsui, T., Miyashita, Y.
  • Journal Title: 2008 Neuroscience Meeting Planner Washington, DC: Society for Neuroscience
  • Peer Reviewed
• [Journal Article] Neuronal activities in area 35 of macaque perirhinal cortex during a pair association task (2008)
  • Author(s): Fujimichi, R., Takeda, M., Naya, Y., Koyano K.W., Takeuchi, D., Miyashita, Y.
  • Journal Title: Neuroscience Research 61(Suppl.1)
  • Peer Reviewed
• [Journal Article] MRI-based in vivo detection of recording sites marked by electrolysis of an elgiloy electrode (2008)
  • Author(s): Koyano, K.W., Takeda, M., Fujimichi, R., Ohashi, Y., Miyashita, Y.
  • Journal Title: Neuroscience Research 61(Suppl.1)
  • Peer Reviewed
• [Journal Article] Functional characterization of area 35 in the macaque perirhinal cortex during a nair association task (2008)
  • Author(s): Fujimichi, R, Takeda, M, Naya, Y, Koyano, KW, Takeuchi, D, Miyashita, Y.
  • Journal Title: 2008 Neuroscience Meeting Planner
• [Journal Article] Electrolysis of an elgiloy electrode can create MRI-visible metal deposit marks at recording sites (2008)
  • Author(s): Koyano, KW, Machino, A, Takeda, M, Fujimichi, R, Ohashi, Y, Matsui, T, Miyashita, Y.
  • Journal Title: 2008 Neuroscience Meeting Planner
• [Journal Article] Neuronal activities in area 35 of macaque perirhinal cortex during a pair association task (2008)
  • Author(s): Fujimichi, R, Takeda, M, Naya, Y, Koyano KW, Takeuchi, D, Miyashita, Y.
  • Journal Title: Neuroscience Research 61 (Supp1.1)
• [Journal Article] MRI-based in vivo detection of recording sites marked by electrolysis of an elgiloy electrode. (2008)
  • Author(s): Koyano, KW, Takeda, M, Fujimichi, R, Ohashi Y, Miyashita, Y.
  • Journal Title: Neuroscience Research 61 (Supp1.1)
• [Journal Article] MRI-based localization of electrophysiological recording sites within the cerebral cortex at single-voxel accuracy (2007)
  • Author(s): Matsui, T., Koyano, K.W., Koyama, M., Nakahara, K., Takeda, T., Ohashi, Y., Naya, Y., Miyashita, Y.
  • Journal Title: Nature methods 4 Pages: 161-168
  • Peer Reviewed
• [Journal Article] A non-magnetic mini-manipulaor for an MRI-based method for localization of a microelectrode tip within monkey cerebral cortex (2007)
  • Author(s): Koyano, K.W., Ohashi, Y., Matsui, T., Takeda, M., Nakahara, K., Naya, Y., Koyama, M., Watanabe, T., Miyashita, Y.
  • Journal Title: The Journal of Physiological Sciences 57(Suppl.)
  • Peer Reviewed
• [Journal Article] Anon-magnetic mini-manipulator for an MRI-based method for localization of a microelectrode tip within monkey cerebral cortex. (2007)
  • Author(s): Koyano KW, Ohashi Y, Matsui T, Takeda M, Nakahara K, Naya Y, Koyama M, Watanabe T, Miyashita Y.
  • Journal Title: The Journal of Physiological Sciences 4 Pages: 71-71
• [Journal Article] Localization accuracy of microelectrode tip within the monkey temporal cortex using high-resolution MRI. Program No. 694.13. (2006)
  • Author(s): Koyano, K.W., Matsui, T., Naya, Y., Koyama, M., Takeda, M., Nakahara, K., Miyashita, Y.
  • Journal Title: 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience
  • Peer Reviewed
• [Journal Article] Localization of a microelectrode tip within the monkey temporal cortex (2006)
  • Author(s): Koyano, K.W., Matsui, T., Naya, Y., Koyama, M., Takeda, M., Nakahara, K., Miyashita, Y.
  • Journal Title: Neuroscience Research 55(Suppl. 1)
  • Peer Reviewed
• [Journal Article] Localization accuracy of microelectrode tip within the monkey temporal cortex using high-resolution MRI (2006)
  • Author(s): Koyano, K.W., Matsui, T., Naya, Y., Koyama, M., Takeda, M., Nakahara, K., Miyashita Y.
  • Journal Title: 2006 Neuroscience Meeting Planner
• [Journal Article] Localization of a microelectrode tip within the monkey temporal cortex (2006)
  • Author(s): Koyano, K.W., Matsui, T., Naya, Y., Koyama, M., Takeda, M., Nakahara, K., Miyashita, Y.
  • Journal Title: Neuroscience Research 55(Suppl.1)
• [Presentation] MRI-detectable elgiloy deposit markers for in vivo recording site localization: deposit condition, scan parameters and long-term durability (2009)
  • Author(s): Koyano, K.W., Machino, A., Takeda, M., Matsui, T., Fujimichi, R., Ohashi, Y., Miyashita, Y.
  • Organizer: Second global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Yamanashi, Japan
  • Year and Date: 2009-03-07
• [Presentation] Neuronal representation of associative memory in macaque area 35 (perirhinal cortex) (2009)
  • Author(s): Fujimichi, R., Takeda, M., Koyano, K.W., Takeuchi, D., Miyashita, Y.
  • Organizer: Second global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Yamanashi, Japan
  • Year and Date: 2009-03-07
• [Presentation] Neuronal activity coding visual stimulus-stimulus associations in the monkey rhinal cortex (2008)
  • Author(s): Fujimichi, R., Takeda, M., Naya, Y., Koyano, K.W., Takeuchi, D., Miyashita, Y.
  • Organizer: First global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Chiba, Japan
  • Year and Date: 2008-03-08
• [Presentation] From where do we record?: MRI-based in vivo localization methods for microelectrode recordings from the monkey brain (2008)
  • Author(s): Koyano, K.W., Takeda, M., Ohashi, Y., Fujimichi, R., Matsui, T., Naya, Y., Koyama, M., Nakahara, K., Miyashita, Y.
  • Organizer: First global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Chiba, Japan
  • Year and Date: 2008-03-08
• [Presentation] Neuronal activity coding visual stimulus-stimulus associations in the monkey rhinal cortex. (2008)
  • Author(s): Fujimichi R, Takeda M, Naya Y, Koyano KW, Takeuchi D, Miyashita Y.
  • Organizer: First global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Chiba, Japan
  • Year and Date: 2008-03-08
• [Presentation] From where do we record?: MRI-based in vivo localization methods for microelectrode recordings from the monkey brain. (2008)
  • Author(s): Koyano KW, Takeda M, Ohashi Y, Fujimichi R, Matsui T, Naya Y, Koyama M, Nakahara K, Miyashita Y.
  • Organizer: First global COE retreat of "Integrative life science based on the study of biosignaling mechanisms"
  • Place of Presentation: Chiba, Japan
  • Year and Date: 2008-03-08
• [Presentation] In vivo localization of electrophysiological recording sites within the monkey cortex using high-resolution MRI (2007)
  • Author(s): Koyano, K.W., Matsui, T., Koyama, M., Naya, Y., Ohashi, Y., Takeda, M., Nakahara, K., Miyashita, Y.
  • Organizer: University of California San Francisco Neuroscience Retreat
  • Place of Presentation: California, USA
  • Year and Date: 2007-09-24
• [Presentation] In vivo localization of electrophysiological recording sites within the monkey cortex using high-resolution MRI. (2007)
  • Author(s): Koyano KW, Matsui T, Koyama M, Naya Y, Ohashi Y, Takeda M, Nakahara K, Miyashita Y.
  • Organizer: University of California San Francisco Neuroscience Retreat
  • Place of Presentation: California, USA
  • Year and Date: 2007-09-24