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Evaluation of the effects of body fat and leptin on changes in the bone density of female university students

Research Project

Project/Area Number 18700545
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionOkayama Prefectural University

Principal Investigator

KUBOTA Megumi  Okayama Prefectural University, 保健福祉学部, 准教授 (80254564)

Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥5,266,098 (Direct Cost: ¥4,627,768、Indirect Cost: ¥638,330)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,336,098 (Direct Cost: ¥1,027,768、Indirect Cost: ¥308,330)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2006: ¥1,400,000 (Direct Cost: ¥1,400,000)
Keywords健康教育 / 骨粗鬆症 / hVD-SIF1多型 / 隠れ肥満 / エストロゲン レプチン / エストロゲン / レプチン
Research Abstract

Leptin, which is synthesized by lipocytes, is involved in osteoblast differentiation and increases in bone mass, and low body fat is considered to be a more serious risk factor than a reduced load. In this study, we evaluated the effects of body fat, estrogen, and leptin on bone density. In young adult females of the lean or normal body type, Ca absorption from the intestinal tract is strongly genetically affected, but it was suggested that leptin in lipocytes contributes to the maintenance of bone density in hidden obesity.

Report

(5 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (7 results)

All 2009 2008 2006

All Journal Article (3 results) (of which Peer Reviewed: 1 results) Presentation (4 results)

  • [Journal Article] Soybean and soy foods, and Bone health.2009

    • Author(s)
      megumi Kubota, Hirotoshi Shimizu
    • Journal Title

      CLINICAL CALCIUM Vol19No.10

      Pages: 110-115

    • Related Report
      2009 Final Research Report
  • [Journal Article] Significance of calcium supplement for Anti-aging2009

    • Author(s)
      Megumi Kubota
    • Journal Title

      CLINICAL CALCIUM Vol.18, No.7

      Pages: 89-95

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Significance of calcium supplement for Anti-aging2008

    • Author(s)
      megumi Kubota, Hirotoshi Shimizu
    • Journal Title

      CLINICAL CALCIUM Vol18No.7

      Pages: 89-95

    • Related Report
      2009 Final Research Report
  • [Presentation] 女子大学生の骨密度と体脂肪量およびレプチン濃度との関連について2009

    • Author(s)
      久保田恵清水洋利
    • Organizer
      日本栄養食糧学会学術総会
    • Place of Presentation
      長崎県
    • Year and Date
      2009-05-21
    • Related Report
      2009 Final Research Report
  • [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone mineral density of female university students.2008

    • Author(s)
      m e g u m i Kubota
    • Organizer
      国際栄養士会議2008
    • Place of Presentation
      横浜
    • Year and Date
      2008-09-07
    • Related Report
      2009 Final Research Report
  • [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone2008

    • Author(s)
      Megumi Kubota
    • Organizer
      15^<th> International congress of Dietetics
    • Place of Presentation
      Yokohama
    • Year and Date
      2008-09-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] the effects of body fat and leptin on changes in the bone mineral density of female for Anti-aging.2006

    • Author(s)
      meg u m i Kubota, Hirotoshi Shimizu
    • Organizer
      日本抗加齢医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-29
    • Related Report
      2009 Final Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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