Evaluation of the effects of body fat and leptin on changes in the bone density of female university students

• Project/Area Number: 18700545
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Okayama Prefectural University
• Principal Investigator: KUBOTA Megumi Okayama Prefectural University, 保健福祉学部, 准教授 (80254564)
• Project Period (FY): 2006 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥5,266,098 (Direct Cost: ¥4,627,768、Indirect Cost: ¥638,330); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,336,098 (Direct Cost: ¥1,027,768、Indirect Cost: ¥308,330); Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000); Fiscal Year 2006: ¥1,400,000 (Direct Cost: ¥1,400,000)
• Keywords: 健康教育 / 骨粗鬆症 / hVD-SIF1多型 / 隠れ肥満 / エストロゲン レプチン / エストロゲン / レプチン

Research Abstract

Leptin, which is synthesized by lipocytes, is involved in osteoblast differentiation and increases in bone mass, and low body fat is considered to be a more serious risk factor than a reduced load. In this study, we evaluated the effects of body fat, estrogen, and leptin on bone density. In young adult females of the lean or normal body type, Ca absorption from the intestinal tract is strongly genetically affected, but it was suggested that leptin in lipocytes contributes to the maintenance of bone density in hidden obesity.

Research Products

• [Journal Article] Soybean and soy foods, and Bone health. (2009)
  • Author(s): megumi Kubota, Hirotoshi Shimizu
  • Journal Title: CLINICAL CALCIUM Vol19No.10 Pages: 110-115
• [Journal Article] Significance of calcium supplement for Anti-aging (2009)
  • Author(s): Megumi Kubota
  • Journal Title: CLINICAL CALCIUM Vol.18, No.7 Pages: 89-95
  • Peer Reviewed
• [Journal Article] Significance of calcium supplement for Anti-aging (2008)
  • Author(s): megumi Kubota, Hirotoshi Shimizu
  • Journal Title: CLINICAL CALCIUM Vol18No.7 Pages: 89-95
• [Presentation] 女子大学生の骨密度と体脂肪量およびレプチン濃度との関連について (2009)
  • Author(s): 久保田恵清水洋利
  • Organizer: 日本栄養食糧学会学術総会
  • Place of Presentation: 長崎県
  • Year and Date: 2009-05-21
• [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone mineral density of female university students. (2008)
  • Author(s): m e g u m i Kubota
  • Organizer: 国際栄養士会議2008
  • Place of Presentation: 横浜
  • Year and Date: 2008-09-07
• [Presentation] Evaluation of the effects of body fat and leptin on changes in the bone (2008)
  • Author(s): Megumi Kubota
  • Organizer: 15^<th> International congress of Dietetics
  • Place of Presentation: Yokohama
  • Year and Date: 2008-09-07
• [Presentation] the effects of body fat and leptin on changes in the bone mineral density of female for Anti-aging. (2006)
  • Author(s): meg u m i Kubota, Hirotoshi Shimizu
  • Organizer: 日本抗加齢医学会総会
  • Place of Presentation: 東京
  • Year and Date: 2006-05-29