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Interaction among human chromosomes and its relationship to spatial organization of chromosomes in a nucleus

Research Project

Project/Area Number 18710159
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field 基礎ゲノム科学
Research InstitutionHokkaido University

Principal Investigator

KOYANAGI Kanako  Hokkaido University, 大学院情報科学研究科, 准教授 (20362840)

Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,657,675 (Direct Cost: ¥4,447,675、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,747,675 (Direct Cost: ¥1,747,675)
Fiscal Year 2006: ¥2,000,000 (Direct Cost: ¥2,000,000)
Keywords遺伝子 / ゲノム / 進化 / 染色体 / 核内配置
Research Abstract

本研究の目的は、ヒトゲノム情報解析から染色体間の相互作用を示す情報を抽出し、核内における染色体の核内配置との関連性を検証することである。本研究では、染色体間の相互作用を示す情報として、ヒトゲノム中にみられるプロセス型偽遺伝子とゲノム内重複領域の染色体分布を解析し、染色体間の偏りを検出した。またこの研究の過程において、種特異的な重複領域を高精度に同定する目的で、分子進化解析に基づくゲノム直系領域の同定方法を開発した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (4 results)

All 2009 2008 2007

All Journal Article (4 results) (of which Peer Reviewed: 4 results)

  • [Journal Article] Highly diversified molecular evolution of downstream transcription start sites in rice and Arabidopsis2009

    • Author(s)
      Tanaka T, Koyanagi KO, Itoh T.
    • Journal Title

      Plant Physiol 149(3)

      Pages: 1316-24

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evola : Ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees2008

    • Author(s)
      Matsuya A, Sakate R, Kawahara Y, Koyanagi KO, Sato Y, Fujii Y, Yamasaki C, Habara T, Nakaoka H, Todokoro F, Yamaguchi K, Endo T, Oota S, Makalowski W, Ikeo K, Suzuki Y, Hanada K, Hashimoto K, Hirai M, Iwama H, Saitou N, Hiraki AT, Jin L, Kaneko Y, Kanno M, Murakami K, Noda AO, Saichi N, Sanbonmatsu R, Suzuki M, Takeda J, Tanaka M, Gojobori T, Imanishi T, Itoh T
    • Journal Title

      Nucleic Acids Research 36

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts2008

    • Author(s)
      Yamasaki C et al. (12番目、他137名)
    • Journal Title

      Nucleic Acids Research 36

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Frequent emergence and functional resurrection of processed pseudogenes in the human and mouse genomes2007

    • Author(s)
      Sakai H, Koyanagi KO, Imanishi T, Itoh T, Gojobori T
    • Journal Title

      Gene 389(2)

      Pages: 196-203

    • Related Report
      2008 Final Research Report
    • Peer Reviewed

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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