Identification of a cell death inducible factor in autophagy-defective plants
Project/Area Number |
18770040
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
植物生理・分子
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Research Institution | The Institute of Physical and Chemical Research (2007-2008) National Institute for Basic Biology (2006) |
Principal Investigator |
YOSHIMOTO Koki The Institute of Physical and Chemical Research, 植物免疫研究チーム, 基礎科学特別研究員 (40399316)
|
Project Period (FY) |
2006 – 2008
|
Project Status |
Completed (Fiscal Year 2008)
|
Budget Amount *help |
¥3,780,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2006: ¥1,200,000 (Direct Cost: ¥1,200,000)
|
Keywords | オートファジー / 液胞 / オルガネラ / 細胞死 / 老化 / タンパク質分解 / サリチル酸 |
Research Abstract |
オートファジーは,細胞内タンパク質を液胞に送り込み,分解する現象であり,液胞分解機構の中心的な役割を担っている.申請者は,オートファジー不能植物(ATG遺伝子破壊株)の表現型解析から,高等植物ではタンパク質のリサイクリング・アミノ酸の供給源としてのオートファジーの生理的役割に加え,細胞死において植物ならではの役割が存在することを明らかにした.
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Report
(4 results)
Research Products
(23 results)
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[Journal Article] Autophagy plays a role in chloroplast degradation during leaf senescence in individually darkened leaves2009
Author(s)
Wada, S., Ishida, H., Izumi, M., Yoshimoto, K., Ohsumi, Y., Mae, T., Makino, A.
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Journal Title
Plant Physiol. 149
Pages: 885-893
Related Report
Peer Reviewed
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[Journal Article] OsATG10b, an Autophagosome component, is needed for cell survival against oxidative stresses in rice2009
Author(s)
Shin, J. H., Yoshimoto, K., Ohsumi, Y., Jeon, J. S., An, G.
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Journal Title
Mol. Cells 27
Pages: 67-74
Related Report
Peer Reviewed
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[Journal Article] Mobilization of Rubisco and stromal-localized fluorescent proteins of chloroplasts to the vacuole by ATG gene-dependent autophagic process2008
Author(s)
Ishida, H., Yoshimoto, K., Izumi, M., Reisen, D., Yano, Y., Makino, A., Ohsumi, Y., Hanson, M. R., Mae, T.
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Journal Title
Plant Physiol. 148
Pages: 142-155
Related Report
Peer Reviewed
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[Journal Article] In vitro reconstitution of plant ATG8 and ATG12 conjugation systems essential for plant autophagy2008
Author(s)
Fujioka, Y., Noda, N. N., Fujii, K., Yoshimoto, K., Ohsumi, Y., Inagaki, F.
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Journal Title
J. Biol. Chem. 283
Pages: 1921-1928
Related Report
Peer Reviewed
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[Journal Article] AtATG genes, homologs of yeast autophagy genes, are involved in constitutive autophagy in Arabidopsis root tip cells2006
Author(s)
Inoue, Y, Suzuki, T, Hattori, M, Yoshimoto, K., Ohsumi, Y, Moriyasu, Y.
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Journal Title
Plant Cell Physiol. 47
Pages: 1641-1652
Related Report
Peer Reviewed
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