Feasibility of diffusion tensor imaging and tractography of peripheral nerves

• Project/Area Number: 18790868
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: The University of Tokyo (2008); University of Tsukuba (2006-2007)
• Principal Investigator: KUNIMATSU Akira The University of Tokyo, 医学部附属病院, 助教 (20323553)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥2,550,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2007: ¥600,000 (Direct Cost: ¥600,000); Fiscal Year 2006: ¥1,300,000 (Direct Cost: ¥1,300,000)
• Keywords: 放射線 / 脳・神経

Research Abstract

脳を対象として広く応用されている拡散テンソルMRI画像の、ヒト末梢神経への応用を試みた。植物やポリエステル繊維などによる末梢神経模擬体(ファントム)によるMRI撮像条件の調整の後、ヒト正中神経の拡散テンソルMRIでの画像化(トラクトグラフィー)を試み、実現可能性を検討した。正中神経の画像化は可能であったが、骨の近傍での画像化がうまく行かない傾向があり、今後解決すべき問題点として浮き彫りになった。

Research Products

• [Journal Article] Integrity of limbic system network in schizophrenia : A tract-specific analysis (2009)
  • Author(s): Kunimatsu A, Kunimatsu N, Aoki S, ほか7名
  • Journal Title: Proceedings of ISMRM 3387
  • Peer Reviewed
• [Journal Article] Validation of diffusion tensor imaging and tractography of the human peripheral nerve using small-diameter ex vivo phantoms (2008)
  • Author(s): Kunimatsu A, Yamaguchi M, Okamoto Y, ほか5名
  • Journal Title: Proceedings of ISMRM 3304
  • Peer Reviewed
• [Journal Article] Normal right-to-left asymmetry in fractional anisotropy of superior occipitofrontal fasciculus disappears in schizophrenia (2007)
  • Author(s): Kunimatsu A, Kunimatsu N, Aoki S, ほか6名
  • Journal Title: Proceedings of ISMRM 3743
  • Peer Reviewed
• [Presentation] Integrity of limbic system network in schizophrenia : A tract-specific analysis (2009)
  • Author(s): Kunimatsu A.
  • Organizer: ISMRM 17^<th> Scientific Meeting & Exihibition
  • Place of Presentation: Honolulu, USA.
• [Presentation] Validation of diffusion tensor imaging and tractography of the human peripheral nerve using small-diameter ex vivo phantoms (2008)
  • Author(s): 國松聡, ほか
  • Organizer: 16^<th> ISMRM Scientific Meeting & Exhibition
  • Place of Presentation: トロント(カナダ)
  • Year and Date: 2008-05-06
• [Presentation] Validation of diffusion tensor imaging and tractography of the human peripheral nerve using small-diameter ex vivo phantoms (2008)
  • Author(s): Kunimatsu A.
  • Organizer: ISMRM 16^<th> Scientific Meeting & Exihibition
  • Place of Presentation: Toronto, Canada
• [Presentation] Normal right-to-left asymmetry in fractional anisotropy of superior occipitofrontal fasciculus disappears in schizophrenia (2007)
  • Author(s): Kunimatsu A.
  • Organizer: Joint Annual Meeting ISMRM-ESMRMB
  • Place of Presentation: Berlin, Germany