Evaluation of the replication mechanism of chlamydia by yeast expression system

• Project/Area Number: 18791384
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Kagoshima University
• Principal Investigator: KANBARA Kenji Kagoshima University, 大学院・医歯学総合研究科, 助教 (60305141)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,800,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥900,000 (Direct Cost: ¥900,000); Fiscal Year 2006: ¥1,600,000 (Direct Cost: ¥1,600,000)
• Keywords: クラミジア / TNFα / TNF-α / Pg / 病原因子 / P.g / 動脈硬化 / TACE

Research Abstract

クラミジアを始めとし、細菌感染によって産生されるTNFαを効果的に抑制できた。この事は、動脈硬化などの発生を抑制的に作用する事が考えられ、クアミジアを始めとする各種細菌の相乗的な炎症反応を抑制による心疾患を始めとするリスク軽減に、有効である事が考えられた。

Research Products

• [Journal Article] Surface Properties and Biocompatibility of Acid-etched Titanium (2008)
  • Author(s): Iwaya Y, Machigashira M, Kanbara K, Miyamoto M, Noguchi K, Izumi Y, Ban S.
  • Journal Title: Dent Mater J 27(3) Pages: 415-421
  • NAID: 110006742425
  • Peer Reviewed
• [Journal Article] Hydrogen sulfide inhibits cell proliferation and induces cell cycle arrest via an elevated p21 Cipllevel in Ca9-22 cells (2008)
  • Author(s): Takeuchi H, Setoguchi T, MachigashiraM, Kanbara K, Izumi Y
  • Journal Title: J Periodontal Res 43(1) Pages: 90-5
  • Peer Reviewed
• [Journal Article] Apatite coating on zirconia using glass coating technique (2008)
  • Author(s): Yamashita D, Sato H, Miyamoto M, MAchigashira M, Kanbara K, Ban S
  • Journal Title: J Ceram Soc Jpn 116(1349) Pages: 20-22
  • Peer Reviewed
• [Journal Article] Proliferation of Osteoblast-like Cells on Zirconia/alumina Nanocomposite (2008)
  • Author(s): Daisuke Yamashita., Kenji Kanbara., Miho Machigashira., Motoharu Miyamoto., Hideo Sato., Yuichi Izumi., Seiji Ban.
  • Journal Title: Key Engineering Materials Vols 361-363 Pages: 1099-1102
  • NAID: 130006963397
  • Peer Reviewed
• [Journal Article] Apatite coating on zirconia using glass coating technique (2007)
  • Author(s): Yamashita D, Sato H, Miyamoto M, Machigashira M, Kanbara K, Ban S
  • Journal Title: Archives of Bioceramics Research 7 Pages: 269-272
  • Peer Reviewed
• [Journal Article] Evaluation of biocompatibility with bioactive surface modification of Titanium (2006)
  • Author(s): M. Miyamoto, D. Yamashita, H. Kono, H. Takeuchi, K. Kanbara, M. Machigashira, Y. Izumi and S. Ban
  • Journal Title: Archieves of BioCeramics Research 6 Pages: 312-314
  • Peer Reviewed
• [Presentation] Evaluation of biocompatibility with bioactive surface modification of Titanium (2006)
  • Author(s): M. Miyamoto, D. Yamashita, H. Kono, H. Takeuchi, K. Kanbara,M. Machigashira, Y. Izumi and S. Ban
  • Organizer: The 6th Asian BioCeramics Symposium (ABC2006)
  • Place of Presentation: Bangkok, Thailand