Study on application of rapid apatite conversion type calcium phosphate cement for pulpotomy

• Project/Area Number: 18791559
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: The University of Tokushima
• Principal Investigator: KIMURA Natsuko The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 助教 (70335800)
• Project Period (FY): 2006 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,200,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2007: ¥800,000 (Direct Cost: ¥800,000); Fiscal Year 2006: ¥2,100,000 (Direct Cost: ¥2,100,000)
• Keywords: 歯学 / 再生医学 / 細胞・組織

Research Abstract

The rapid apatite conversion type calcium phosphate cement (RAC-CPC) becomes high alkalinity when stiffening, and it becomes neutral and shows no stimulation when it changes to hydroxyapatite. The purpose of this study was : 1. To evaluate the influence of RAC-CPC for the dorsal subcutaneous tissue and to evaluate the pH changes of RAC-CPC. 2. To evaluate pathologically on application of RAC-CPC for pulpotoiny.
It was suggested that RAC-CPC have the ability to the dental pulp stimulates for pulpotomy, but not enough to induce the hard tissue formation.