Physico-chemical approach on the construction of functional denovo cell

• Project/Area Number: 18GS0421
• Research Category: Grant-in-Aid for Creative Scientific Research
• Allocation Type: Single-year Grants
• Research Institution: Kyoto University
• Principal Investigator: YOSHIKAWA Kenichi 京都大学, 大学院・理学研究科, 教授 (80110823)
• Co-Investigator(Kenkyū-buntansha): IMANAKA Tadayuki 立命館大学, 生命科学部, 教授 (30029219) ; AKIYOSHI Kazunari 京都大学, 工学研究科, 教授 (90201285) ; NOMURA Shinichiro 京都大学, 物質-細胞統合システム拠点, 研究員 (50372446) ; SETO Hidenori 高エネルギー加速器研究機構, 教授 (60216546) ; KITAHATA Hiroyuki 千葉大学, 理学部, 講師 (20378532) ; ARUGA Takayuki 東京大学, 工学研究科, 助教 (30452262) ; 稲垣 紫緒 京都大学, 理学研究科, 研究員 (20452261)
• Co-Investigator(Renkei-kenkyūsha): KANAI Tamotsu 京都大学, 工学研究科, 助教 (10346083) ; INAGAKI Shio 京都大学, ベンチャー・ビジネス・ラボラトリー, 研究員 (20452261) ; SATO Yuko 京都大学, 理学研究科, 研究員 (30423528) ; ICHIKAWA Masatoshi 京都大学, 理学研究科, 講師 (40403919) ; TAKINOUE Masahiro 東京大学, 生産技術研究所, 特任研究員 (20511249) ; IMAMURA Hisako 京都大学, 理学研究科, 研究員 (30523790)
• Project Period (FY): 2006 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥516,620,000 (Direct Cost: ¥397,400,000、Indirect Cost: ¥119,220,000); Fiscal Year 2010: ¥83,460,000 (Direct Cost: ¥64,200,000、Indirect Cost: ¥19,260,000); Fiscal Year 2009: ¥83,460,000 (Direct Cost: ¥64,200,000、Indirect Cost: ¥19,260,000); Fiscal Year 2008: ¥114,400,000 (Direct Cost: ¥88,000,000、Indirect Cost: ¥26,400,000); Fiscal Year 2007: ¥114,400,000 (Direct Cost: ¥88,000,000、Indirect Cost: ¥26,400,000); Fiscal Year 2006: ¥120,900,000 (Direct Cost: ¥93,000,000、Indirect Cost: ¥27,900,000)
• Keywords: リポソーム / 人工細胞モデル / 化学物理 / 物性基礎論 / 生物物理 / 自己組織化 / 生命物理 / ゲノムDNA / リポソ-ム / メゾスコピック系 / メソスコピック系

Research Abstract

1) We have successfully constructed a model experimental system exhibiting robust on/off switching on genetic activity accompanied by the structural transition of a giant DNA molecule. 2) It is shown that micro-confinement causes specific phase-segregation. We demonstrated marked acceleration of gene-expression reaction in an artificial model cell. 3) We proposed a novel theoretical model to explain the emergent process of the morphology in multicellular systems.

Research Products

• [Journal Article] Cell-Sized confinement in microspheres accelerates the reaction of gene expression (2012)
  • Author(s): Kato A, Yanagisawa M, Sato YT, Fuiiwara K, Yoshikawa K
  • Journal Title: Scientific Report Volume: 2 Issue: 1 Pages: 283-283
  • DOI: 10.1038/srep00283
  • Peer Reviewed
• [Journal Article] Large-scale vortex lattice emerging from collectively moving microtubules (2012)
  • Author(s): Y.Sumino, K.H.Nagai, Y.Shitaka, D.Tanaka, K.Yoshikawa, H.Chate, K.Oiwa
  • Journal Title: Nature Volume: 483 Pages: 448-452
  • Peer Reviewed
• [Journal Article] How environmental solution conditions determine the compaction velocity of single DNA molecules (2012)
  • Author(s): K.Hirano, M.Ichikawa, T.Ishido, M.Ishikawa, Y.Baba, K.Yoshikawa
  • Journal Title: Nucleic Acids Research Volume: 40 Pages: 284-289
  • Peer Reviewed
• [Journal Article] Critical behavior of megabase-size DNA toward the transition into a compact state (2011)
  • Author(s): Yuko Yoshikawa, Yuki Suzuki, Kozo Yamada, Wakao Fukuda, Kenichi Yoshikawa, Kunio Takeyasu, Tadayuki Imanaka
  • Journal Title: Journal of Chemical Physics Volume: 135 Issue: 22 Pages: 225101-225107
  • DOI: 10.1063/1.3666845
  • Peer Reviewed
• [Journal Article] Transformation of acto HMM assembly confined in cell-sized liposome (2011)
  • Author(s): K. Takiguchi, M. Negishi, Y. T.-Takiguchi, M. Homma, and K. Yoshikawa
  • Journal Title: Langmuir Volume: 27(18) Issue: 18 Pages: 11528-11535
  • DOI: 10.1021/la2016287
  • Peer Reviewed
• [Journal Article] Synthesis and in situ insertion of a site-specific fluorescently labeled membrane protein into cell-sized liposomes (2011)
  • Author(s): T. Ohtsuka, S. Neki, T. Kanai, K. Akiyoshi, S. M. Nomura, T. Ohtsuki
  • Journal Title: Analytical Biochemistry Volume: 418 Issue: 1 Pages: 97-101
  • DOI: 10.1016/j.ab.2011.06.026
  • Peer Reviewed
• [Journal Article] Critical behavior of megabase-size DNA toward transition into a compact state (2011)
  • Author(s): Y.Yoshikawa, Y.Suzuki, K.Yamada, W.Fukuda, K.Yoshikawa, K.Takeyasu, T.Imanaka
  • Journal Title: Journal of Chemical Physics Volume: 135 Pages: 225101-225101
  • NAID: 120003726127
  • Peer Reviewed
• [Journal Article] Highly Efficient DNA Compaction Mediated by an In Vivo Antitumor-Active Tetrazolato-Bridged Dinuclear Platinum(II) Complex (2011)
  • Author(s): Y.Yoshikawa, S.Komeda, M.Uemura, T.Kanbe, M.Chikuma, K.Yoshikawa, T.Imanaka
  • Journal Title: Inorganic Chemistry Volume: 50 Pages: 11729-11735
  • Peer Reviewed
• [Journal Article] Unraveling DNA dynamics using atomic force microscopy (2011)
  • Author(s): Y.Suzuki, Y.Yoshikawa, S.H.Yoshimura, K.Yoshikawa, K.Takeyasu
  • Journal Title: WIREs Nanomedicine and Nanobiotechnology Volume: 3 Pages: 574-588
  • Peer Reviewed
• [Journal Article] Transformation of ActoHMM Assembly Confined in Cell-Sized Liposome (2011)
  • Author(s): K.Takiguchi, M.Negishi, Y.Tanaka-Takiguchi, M.Homma, K.Yoshikawa
  • Journal Title: Langmuir Volume: 27 Pages: 11528-11535
  • Peer Reviewed
• [Journal Article] Oriented Reconstitution of a Membrane Protein in a Giant Unilamellar Vesicle : Experimental Verification with the Potassium Channel KcsA (2011)
  • Author(s): M.Yanagisawa, M.Iwamoto, A.Kato, K.Yoshikawa, S.Oiki
  • Journal Title: Journal of the American Chemical Society Volume: 133 Pages: 11774-11779
  • Peer Reviewed
• [Journal Article] Confinement causes opposite effects on the folding transition of a single polymer chain depending on its stiffness (2011)
  • Author(s): Y.Higuchi, K.Yoshikawa
  • Journal Title: Physical Review E Volume: 84 Pages: 21924-21924
  • Peer Reviewed
• [Journal Article] Phase behavior of crowded like-charged mixed polyelectrolytes in a cell-sized sphere (2011)
  • Author(s): M.Negishi, M.Ichikawa, M.Nakajima, M.Kojima, T.Fukuda, K.Yoshikawa
  • Journal Title: Physical Review E Volume: 83 Pages: 61921-61921
  • Peer Reviewed
• [Journal Article] Salt Has a Biphasic Effect on the Higher-Order Structure of a DNA-Protamine Complex (2011)
  • Author(s): N.Makita, Y.Yoshikawa, Y.Takenaka, T.Sakaue, M.Suzuki, C.Watanabe, T.Kanai, T.Kanbe, T.Imanaka, K.Yoshikawa
  • Journal Title: Journal of Physical Chemistry B Volume: 115 Pages: 4453-4459
  • Peer Reviewed
• [Journal Article] Thermococcus kodakarensis as a Host for Gene Expression and Protein Secretion (2011)
  • Author(s): R.Takemasa, Y.Yokooji, A.Yamatsu, H.Atomi, T.Imanaka
  • Journal Title: Applied and Environmental Microbiology Volume: 77 Pages: 2392-2398
  • Peer Reviewed
• [Journal Article] Molecular bases of thermophily in hyperthermophiles(謝辞無し) (2011)
  • Author(s): T.Imanaka
  • Journal Title: Proceedings of the Japan Academy, Series B Volume: 87 Pages: 587-602
  • Peer Reviewed
• [Journal Article] Biochemical and genetic characterization of the three metabolic routes in Thermococcus kodakarensis linking glyceraldehyde 3-phosphate and 3-phosphoglycerate(謝辞無し) (2011)
  • Author(s): K.Matsubara, Y.Yokooji, H.Atomi, T.Imanaka
  • Journal Title: Molecular Microbiology Volume: 81 Pages: 1300-1312
  • Peer Reviewed
• [Journal Article] Cyclodextrin-responsive nanogel as an artificial chaperone for horseradish peroxidase (2011)
  • Author(s): S.Sawada, Y.Sasaki, Y.Nomura, K.Akiyoshi
  • Journal Title: Colloid and Polymer Science Volume: 289 Pages: 685-691
  • Peer Reviewed
• [Journal Article] Polysaccharide nanogel gene delivery system with endosome-escaping function : Co-delivery of plasmid DNA and phospholipase A_2 (2011)
  • Author(s): S.Toita, S.Sawada, K.Akiyoshi
  • Journal Title: Journal of Controlled Release Volume: 155 Pages: 54-59
  • Peer Reviewed
• [Journal Article] Cadherin-integrated liposomes with potential application in a drug delivery system (2011)
  • Author(s): K.Kamiya, K.Tsumoto, T.Yoshimura, K.Akiyoshi
  • Journal Title: Biomaterials Volume: 32 Pages: 9899-9907
  • Peer Reviewed
• [Journal Article] DNA compaction in a crowded environment with negatively charged proteins (2010)
  • Author(s): M. K. Krotova, V. V. Vasilevskaya, N. Makita, K. Yoshikawa, and A. R. Khokhlov
  • Journal Title: Physical Review Letters Volume: 105(12) Issue: 12 Pages: 128302-128302
  • DOI: 10.1103/physrevlett.105.128302
  • Peer Reviewed
• [Journal Article] Characteristic effect of an anticancer dinuclear platinum(II) complex on the higher-order structure of DNA (2010)
  • Author(s): N. Kida, Y. Katsuda, Y. Yoshikawa, S. Komeda, T. Sato, Y. Saito, M. Chikuma, M. Suzuki, T. Imanaka, K. Yoshikawa
  • Journal Title: Journal of Biological Inorganic Chemistry Volume: 15(5) Issue: 5 Pages: 701-707
  • DOI: 10.1007/s00775-010-0637-y
  • Peer Reviewed
• [Journal Article] Rotary motion driven by a direct current electric field (2010)
  • Author(s): M. Takinoue, Yu Atsumi, and K. Yoshikawa
  • Journal Title: Applied Physics Letters Volume: 96(10) Issue: 10 Pages: 104105-104105
  • DOI: 10.1063/1.3358385
  • NAID: 120002511324
  • Peer Reviewed
• [Journal Article] Direct integration of cell-free synthesized connexin-43 into liposomes utilizing chaperone-like function of lipo-somes (2010)
  • Author(s): Y. Moritani, S. M. Nomura, I. Morita and K. Akiyoshi
  • Journal Title: FEBS Journal Volume: 277 Issue: 16 Pages: 3343-332
  • DOI: 10.1111/j.1742-4658.2010.07736.x
  • Peer Reviewed
• [Journal Article] Comparative study of kinetics on DNA double-strand break induced by photo- and gamma-Irradiation : Protective effect of water-soluble flavonoids (2010)
  • Author(s): Y.Yoshikawa, T.Mori, M.Suzuki, T.Imanaka, K.Yoshikawa
  • Journal Title: Chemical Physics Letters Volume: 501 Pages: 146-151
  • Peer Reviewed
• [Journal Article] Dual biosynthesis pathway for longer chain polyamines in hyperthermophilic archaeon Thermococcus kodakarensis (2010)
  • Author(s): N.Morimoto, W.Fukuda, N.Nakajima, T.Masuda, Y.Terui, T.Kanai, T.Oshima, T.Imanaka, S.Fujiwara
  • Journal Title: Journal of Bacteriology Volume: 192 Pages: 4991-5001
  • Peer Reviewed
• [Journal Article] Characteristic effect of an anticancer dinuclear platinum(II) complex on the higher-order structure of DNA (2010)
  • Author(s): N.Kida, Y.Katsuda, Y.Yoshikawa, S.Komeda, T.Sato, Y.Saito, M.Chikuma, M.Suzuki, T.Imanaka, K.Yoshikawa
  • Journal Title: Journal of Biological Inorganic Chemistry Volume: 15 Pages: 701-707
  • Peer Reviewed
• [Journal Article] Structure-based Catalytic Optimization of a Type III Rubisco from a Hyperthermophile(謝辞無し) (2010)
  • Author(s): Y.Nishitani, S.Yoshida, M.Fujihashi, K.Kitagawa, T.Doi, H.Atomi, T.Imanaka, K.Miki
  • Journal Title: Journal of Biological Chemistry Volume: 285 Pages: 39339-39347
  • Peer Reviewed
• [Journal Article] Polysaccharide nanogel-cyclodextrin system as an artificial chaperone for in vitro protein synthesis of green fluorescent protein (2010)
  • Author(s): Y.Sasaki, Y.Nomura, S.Sawada, K.Akiyoshi
  • Journal Title: Polymer Journal Volume: 42 Pages: 823-828
  • NAID: 10026687316
  • Peer Reviewed
• [Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines (2010)
  • Author(s): T.Nochi, Y.Yuki, H.Takahashi, S.Sawada, M.Mejima, T.Kohda, N.Harada, I.G.Kong, A.Sato, N.Kataoka, D.Tokuhara, S.Kurokawa, Y.Takahashi, H.Tsukada, S.Kozaki, K.Akiyoshi, H.Kiyono
  • Journal Title: Nature Materials Volume: 9 Pages: 572-578
  • Peer Reviewed
• [Journal Article] Nano-Encapsulation of Lipase by Self-Assembled Nanogels : Induction of High Enzyme Activity and Thermal Stabilization (2010)
  • Author(s): S.Sawada, K.Akiyoshi
  • Journal Title: Macromolecular Bioscience Volume: 10 Pages: 353-358
  • Peer Reviewed
• [Journal Article] Direct integration of cell-free-synthesized connexin-43 into liposomes and hemichannel formation (2010)
  • Author(s): Y.Moritani, S.M.Nomura, I.Morita, K.Akiyoshi
  • Journal Title: FEBS Journal Volume: 277 Pages: 3343-3352
  • Peer Reviewed
• [Journal Article] リポソーム/細胞間の分子通信 (2010)
  • Author(s): 野村慎一郎、森谷優貴、秋吉一成
  • Journal Title: 日本ロボット学会誌(特集「分子ロボティクス」) Volume: 28 Pages: 1176-1177
  • NAID: 10027648179
  • Peer Reviewed
• [Journal Article] Phase separation of a mixture of charged and neutral lipids on a giant vesicle induced by small cations (2010)
  • Author(s): N.Shimokawa, M.Hishida, H.Seto, K.Yoshikawa
  • Journal Title: Chemical Physics Letters Volume: 496 Pages: 59-63
  • NAID: 120002511327
  • Peer Reviewed
• [Journal Article] Anomalous roughening of curvature-driven growth with a variable interface window (2010)
  • Author(s): Y.J.Chen, Y.Nagamine, T.Yamaguchi, K.Yoshikawa
  • Journal Title: Physical Review E Volume: 82 Pages: 21604-21604
  • Peer Reviewed
• [Journal Article] Quantum dot probes for observation of single molecule DNA and a synthetic polyelectrolyte higher-order structure (2010)
  • Author(s): N.Chen, A.A.Zinchenko, Y.Yamazaki, Y.Yoshikawa, S.Murata, K.Yoshikawa
  • Journal Title: Soft Matter Volume: 6 Pages: 2834-2841
  • Peer Reviewed
• [Journal Article] Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly (N-i sopropylacrylamide) (2010)
  • Author(s): N.Chen, A.A.Zinchenko, S.Kidoaki, S.Murata, K.Yoshikawa
  • Journal Title: Langmuir Volume: 26 Pages: 2995-2998
  • Peer Reviewed
• [Journal Article] Large system in a small cell : A hypothetical pathway from a microscopic stochastic process towards robust genetic regulation (2010)
  • Author(s): H.Nagahara, K.Yoshikawa
  • Journal Title: Chemical Physics Letters Volume: 494 Pages: 88-94
  • Peer Reviewed
• [Journal Article] A non-equilibrium quasistationary state in an ionic liquid caused by a focused laser (2010)
  • Author(s): N.Iguchi, A.Datta, K.Yoshikawa, Y.Yoshida, G.Saito
  • Journal Title: Chemical Physics Letters Volume: 485 Pages: 110-113
  • Peer Reviewed
• [Journal Article] Phase Separation on a Phospholipid Membrane Inducing a Characteristic Localization of DNA Accompanied by Its Structural Transition (2010)
  • Author(s): A.Kato, A.Tsuji, M.Yanagisawa, D.Saeki, K.Juni, Y.Morimoto, K.Yoshikawa
  • Journal Title: Journal of Physical Chemistry Letters Volume: 1 Pages: 3391-3395
  • Peer Reviewed
• [Journal Article] DNA Compaction in a Crowded Environment with Negatively Charged Proteins (2010)
  • Author(s): M.K.Krotova, V.V.Vasilevskaya, N.Makita, K.Yoshikawa, A.R.Khokhlov
  • Journal Title: Physical Review Letters Volume: 105 Pages: 128302-128302
  • Peer Reviewed
• [Journal Article] Torsional effect on the wrapping transition of a semiflexible polymer around a core as a model of nucleosome (2010)
  • Author(s): Y.Higuchi, T.Sakaue, K.Yoshikawa
  • Journal Title: Physical Review E Volume: 82 Pages: 31909-31909
  • Peer Reviewed
• [Journal Article] Compaction of DNA Induced by Like-Charge Protein : Opposite Salt-Effect against the Polymer-Salt-Induced Condensation with Neutral Polymer (2010)
  • Author(s): K.Yoshikawa, S.Hirota, N.Makita, Y.Yoshikawa
  • Journal Title: Journal of Physical Chemistry Letters Volume: 1 Pages: 1763-1766
  • Peer Reviewed
• [Journal Article] Traveling wave of segregation in a highly filled rotating drum (2010)
  • Author(s): S.Inagaki, K.Yoshikawa
  • Journal Title: Physical Review Letters Volume: 105 Pages: 118001-118001
  • Peer Reviewed
• [Journal Article] Finite-Width Bundle is Most Stable in a Solution with Salt (2010)
  • Author(s): T.Saito, K.Yoshikawa
  • Journal Title: Journal of Chemical Physics Volume: 133 Pages: 45102-45102
  • Peer Reviewed
• [Journal Article] Cooperation between giant DNA molecules and actin filaments in a microsphere (2010)
  • Author(s): M.Negishi, T.Sakaue, K.Takiguchi, K.Yoshikawa
  • Journal Title: Physical Review E Volume: 81 Pages: 51921-51921
  • Peer Reviewed
• [Journal Article] Rotary motion driven by a direct current electric field (2010)
  • Author(s): M.Takinoue, Y.Atsumi, K.Yoshikawa
  • Journal Title: Applied Physics Letters Volume: 96 Pages: 104105-104105
  • NAID: 120002511324
  • Peer Reviewed
• [Journal Article] Cleavage pattern of DNA caused by endonuclease : Theoretical modeling and experimental verification (2010)
  • Author(s): S.Inagaki, L.Liu, M.Takinoue, K.Yoshikawa
  • Journal Title: Applied Physics Letters Volume: 96 Pages: 63701-63701
  • Peer Reviewed
• [Journal Article] In Vitro HIV-1 Selective Integration into the Target Sequence and Decoy-Effect of the Modified Sequence (2010)
  • Author(s): T.Tsuruyama, T.Nakai, T.Hiratsuka, G.Jin, T.Nakamura, K.Yoshikawa
  • Journal Title: PLoS ONE Volume: 5
  • NAID: 120002661508
  • Peer Reviewed
• [Journal Article] Conformational transition of giant DNA in a confined space surrounded by a phospholipid membrane (2009)
  • Author(s): A. Kato, E. Shindo, T. Sakaue, A. Tsuji, and K. Yoshikawa
  • Journal Title: Biophysical Journal Volume: 97(6) Issue: 6 Pages: 1678-1686
  • DOI: 10.1016/j.bpj.2009.06.041
  • Peer Reviewed
• [Journal Article] Protein synthesis in giant liposomes using the in vitro translation system of The rmococcus kodakaraensis (2009)
  • Author(s): K. Yamaji, T. Kanai, S. M. Nomura, K. Akiyoshi, M. Negishi, Y. Chen, H. Atomi, K. Yoshikawa, T. Imanaka
  • Journal Title: IEEE Transactions on Nano Bioscience Volume: 8(4) Issue: 4 Pages: 325-331
  • DOI: 10.1109/tnb.2009.2035278
  • Peer Reviewed
• [Journal Article] DNA compaction induced by neutral polymer is retarded more effectively by divalent anion than monovalent anion (2009)
  • Author(s): T. Saito, T. Iwaki and K. Yoshikawa
  • Journal Title: Biophys. J 96 Pages: 1068-1075
• [Journal Article] Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes (2009)
  • Author(s): M. Kaneda, S. -i. M. Nomura, S. Ichinose, S. Kondo, K. Nakahama, K. Akiyoshi and I. Morita
  • Journal Title: Biomaterials (in press)
• [Journal Article] Small anion with higher valency retards the compaction of DNA in the presence of multivalent cation (2009)
  • Author(s): T.Saito, T.Iwaki, K.Yoshikawa
  • Journal Title: Biophys.J 96 Pages: 1068-1075
  • Peer Reviewed
• [Journal Article] Emergence of Superstructures from a Homogeneous Lipid Sphere (2009)
  • Author(s): M.Negishi, H.Kitahata, K.Yoshikawa
  • Journal Title: J.Phys.Chem.B 113 Pages: 3264-3268
  • Peer Reviewed
• [Journal Article] Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes (2009)
  • Author(s): M.Kaneda, S.-i.M.Nomura, S.Ichinose, S.Kondo, K.Nakahama, K.Akiyoshi, I.Morita
  • Journal Title: Biomaterials 30 Pages: 3971-3997
  • Peer Reviewed
• [Journal Article] Interaction of Nanogel with Cyclodextrin or Protein : Study by Dynamic Light Scattering and Small-angle Neutron Scattering (2009)
  • Author(s): N.Inomoto, N.Osaka, T.Suzuki, U.Hasegawa, Y.Ozawa, H.Endo, K.Akiyoshi, M.Shibayama
  • Journal Title: Polymer 50 Pages: 541-546
  • Peer Reviewed
• [Journal Article] Hybrid Nanoapatitby Polysaccharide Nanogel-Templated Mineralization (2009)
  • Author(s): S.Yamane, A.Sugawara, A.Watanabe, K.Akiyoshi
  • Journal Title: J.Bioact.Comp.Polym 24 Pages: 151-168
  • Peer Reviewed
• [Journal Article] Nanogel-Calcium Phosphate Hybrid Nanoparticles with Negative or Positive Charges for Potential Biomedical Applications (2009)
  • Author(s): S.Yamane, A.Sugawara, Y.Sasaki, K.Akiyoshi
  • Journal Title: Bull.Chem.Soc.Jpn 82 Pages: 416-418
  • NAID: 10025117012
  • Peer Reviewed
• [Journal Article] 細胞の実空間モデル:生命現象への物理からのアプローチ (2009)
  • Author(s): 滝ノ上正浩, 吉川研一
  • Journal Title: パリティ 23 Pages: 70-72
• [Journal Article] アーキアのゲノムからみえるもの (2009)
  • Author(s): 跡見晴幸, 福居俊昭, 金井保, 今中忠行
  • Journal Title: 蛋白質核酸酵素 54 Pages: 120-126
• [Journal Article] Direct preparation of giant proteo-liposomes by in vitro membrane protein synthesis (2008)
  • Author(s): S. -i. M. Nomura, S. Kondoh, W. Asayama, A. Asada, S. Nishikawa and K. Akiyoshi
  • Journal Title: J. Biotech 133 Pages: 190-195
• [Journal Article] Archaeal RNA polymerase subunits E and F are not required for transcription in vitro, but a Thermococcus kodakarensis mutant lacking subunit F is temperature-senseitive (2008)
  • Author(s): A.Hirata, T.Kanai, T.J.Santangelo, M.Tajiri, K.Manabe, J.N.Reeve, T.Imanaka, K.S.Murakami
  • Journal Title: Mol.Microbiol 70 Pages: 623-633
  • Peer Reviewed
• [Journal Article] How Does the Mobility of Phospholipid Molecules at a Water/Oil Interface Reflect the Viscosity of the Surrounding Oil? (2008)
  • Author(s): M.Negishi, H.Seto, M.Hase, K.Yoshikawa
  • Journal Title: Langmuir 24 Pages: 8431-8434
  • Peer Reviewed
• [Journal Article] DNA compactionin ducedbyneutral polymer is retarded more effectively by divalentanion than monovalentanion (2008)
  • Author(s): T.Saito, T.Iwaki, K.Yoshikawa
  • Journal Title: Chem.Phys.Lett. 465 Pages: 40-44
  • Peer Reviewed
• [Journal Article] Chain length dependence of folding transition in a semiflexible homo-polymer chain : Appearance of a core-shell structure (2008)
  • Author(s): Y.Higuchi, T.Sakaue, K.Yoshikawa
  • Journal Title: Chem.Phys.Lett. 461 Pages: 42-46
  • Peer Reviewed
• [Journal Article] Bending modulus of lipid bilayers in liquid-crystalline phase including anomalous swelling regime estimated by NSE experiments (2008)
  • Author(s): H.Seto, N.L.Yamada, M.Nagao, M.Hishida, T.Takeda
  • Journal Title: Eur.Phys.J.E-Soft Matter 26 Pages: 217-223
  • Peer Reviewed
• [Journal Article] In situ analysis of the higher-order genome structure in a single Escherichia coli cell (2008)
  • Author(s): E.Shindo, K.Kubo, R.L.Ohniwa, K.Takeyasu, K.Yoshikawa.
  • Journal Title: J.Biotech. 133 Pages: 172-176
  • Peer Reviewed
• [Journal Article] Expression profiles and physiological roles of two types of molecular chaperonins from the hyperthermophilic archaeon, Thermococcus (2008)
  • Author(s): S.Fujiwara, R.Aki, M.Yoshida, H.Higashibata, T.Imanaka, W.Fukuda.
  • Journal Title: Appl.Environ.Microbiol. 74 Pages: 7306-7312
  • Peer Reviewed
• [Journal Article] Expression profiles and physiological roles of two types of prefoldins from the hyperthermophilic archaeon Thermococcus kodakaraensis (2008)
  • Author(s): A.Danno, W.Fukuda, M.Yoshida, R.Aki, T.Tanaka, T.Kanai, T.Imanaka, S.Fujiwara.
  • Journal Title: J.Mol.Biol. 382 Pages: 298-311
  • Peer Reviewed
• [Journal Article] Effective approaches for the production of heterologous proteins using the Thermococcus kodakaraensis-based translation system (2008)
  • Author(s): T.Endoh, T.Kanai, T.Imanaka
  • Journal Title: J.Biotech. 133 Pages: 177-182
  • Peer Reviewed
• [Journal Article] Direct preparation of giant proteo-liposomes by in vitro membrane protein synthesis (2008)
  • Author(s): S.-i.M.Nomura, S.Kondoh, W.Asayama, A.Asada, S.Nishikawa, K.Akiyoshi
  • Journal Title: J.Biotech. 133 Pages: 190-195
  • Peer Reviewed
• [Journal Article] Protein-conjugated QD effectively delivered into living cells by a cationic nanogel (2008)
  • Author(s): S.Toita, U.Hasegawa, H.Koga, I.Sekiya, T.Muneta, K.Akiyoshi.
  • Journal Title: J.Nanosci.Nanotech. 8 Pages: 2279-2285
  • Peer Reviewed
• [Journal Article] Thermo-responsive hydrogels with nanodomains : rapid shrinking of nanogel-crosslinking hydrogel of poly(N-isopropyl acrvlamide) (2008)
  • Author(s): N.Morimoto, T.Ohki, K.Kurita, K.Akiyoshi
  • Journal Title: Macromol.Rapid Comm. 29 Pages: 672-676
  • Peer Reviewed
• [Journal Article] Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) (2008)
  • Author(s): N.Morimoto, X.P.Qiu, F.M.Winnik, K.Akiyoshi
  • Journal Title: Macromolecules 41 Pages: 5985-5987
  • Peer Reviewed
• [Journal Article] Siloxane-crosslinked Polysaccharide Nanogels for Potential Biomedical Applications (2008)
  • Author(s): S.Yamane, Y.Sasaki, K.Akiyoshi
  • Journal Title: Chem.Lett. 37 Pages: 1282-1283
  • NAID: 10024398317
  • Peer Reviewed
• [Journal Article] 細胞機能の実空間モデリング (2008)
  • Author(s): 野村M.慎一郎, 山田彩子, 吉川研一
  • Journal Title: 生物物理 48 Pages: 174-179
  • NAID: 110006684417
• [Journal Article] ナノゲルDDS研究の最前線 (2008)
  • Author(s): 森本展行, 秋吉一成
  • Journal Title: ファルマシア 44 Pages: 764-768
• [Journal Article] 会合性高分子の自己組織化:色材における基礎科学講座(第X講) (2008)
  • Author(s): 菅原彩絵, 秋吉一成
  • Journal Title: J.Jpn.Soc.Colour Mater 81 Pages: 178-184
• [Journal Article] Hydration process of multi-stacked phospholipid bilayers to form giant vesicles (2008)
  • Author(s): M. Hishida, H. Seto, N. L. Yamada, K. Yoshikawa
  • Journal Title: Chemical Physics Letters 455 Pages: 297-302
  • Peer Reviewed
• [Journal Article] Large-scale on-off switching of genetic activity mediated by the folding-unfolding transition in a giant DNA molecule: An hypothesis (2008)
  • Author(s): Y. Takenaka, H. Nagahara, H. Kitahata, K. Yoshikawa
  • Journal Title: Physical Review E 77 Pages: 828031-6
  • Peer Reviewed
• [Journal Article] DNA compaction plays a key role in radioprotection against double-strand breaks as revealed by single-molecule observation (2008)
  • Author(s): Y. Yoshikawa, T. Mori, N. Magome, K. Hibino, K. Yoshikawa
  • Journal Title: Chemical Physics Letters 456 Pages: 80-83
  • Peer Reviewed
• [Journal Article] Archaeal Type III Rubiscos function in a pathway for AMP metabolism (2007)
  • Author(s): T. Sato, H. Atomi and T. Imanaka
  • Journal Title: Science 315 Pages: 1003-1006
• [Journal Article] Spontaneous Generation of Giant Liposomes from an Oil/Water Interface (2007)
  • Author(s): A. Yamada, M. Le Berre, K. Yoshikawa and D. Baigl
  • Journal Title: ChemBioChem 8 Pages: 2215-2218
  • NAID: 120000896668
• [Journal Article] Dynamic Processes in Endocytic Transformation of a Raft-Exhibiting Giant Liposome (2007)
  • Author(s): T. Hamada, Y. Miura, K. Ishii, S. Araki, K. Yoshikawa, M. Vestergaard and M. Takagi
  • Journal Title: J. Phys. Chem B, 111 Pages: 10853-10857
• [Journal Article] A mean field theory for the intermolecular and intramolecular conformational transitions of a single flexible polyelectrolyte chain (2007)
  • Author(s): Chwen-Yang Shew, Kenichi Yoshikawa
  • Journal Title: Journal of Chemical Science 126 Pages: 1449131-9
  • Peer Reviewed
• [Journal Article] How are small ions involved in the compaction of DNA molecules? (2007)
  • Author(s): T. Iwaki, T. Saito, K. Yoshikawa
  • Journal Title: Colloids and Surfaces B: Biointerfaces 56 Pages: 126-133
  • NAID: 120000896360
  • Peer Reviewed
• [Journal Article] Survival versus collapse: Abrupt drop of excitability kills the traveling pulse, while gradual change results in adaptation (2007)
  • Author(s): M. Tanaka, H. Nagahara, H. Kitahata, V. Krinsky, K. Agladze, K. Yoshikawa
  • Journal Title: Physical Review E 76 Pages: 162052-6
  • NAID: 120000896064
  • Peer Reviewed
• [Journal Article] Core-Shell structures in single flexible-semi-flexible block copolymers: Finding the free energy minimum for the folding transition (2007)
  • Author(s): N. Yoshinaga, K. Yoshikawa
  • Journal Title: Journal of Chemical Physics 127 Pages: 449021-5
  • Peer Reviewed
• [Journal Article] Elucidation of conformational hysteresis on a giant DNA (2007)
  • Author(s): C. -Y. Shew, Y. Higuchi, K. Yoshikawa
  • Journal Title: Biopolymers and Biological Systems 127 Pages: 851031-16
  • NAID: 120000899544
  • Peer Reviewed
• [Journal Article] Spontaneous Generation of Giant Liposomes from Oil/Water Interface (2007)
  • Author(s): A. Yamada, M. Le Berre, K. Yoshikawa, D. Bagle
  • Journal Title: ChemBioChem 8 Pages: 2215-2218
  • NAID: 120000896668
  • Peer Reviewed
• [Journal Article] Dissociation of DNA-polycation complex by polyanions and polyampholytes (2007)
  • Author(s): C. Y. Shew, K. Yoshikawa, T. Ito, C. Yoshihara, Y. Koyama
  • Journal Title: Chemical Physics Letters 446 Pages: 59-64
  • NAID: 120000896604
  • Peer Reviewed
• [Journal Article] Wave emission from heterogeneities to control chaos in the heart (2007)
  • Author(s): A. Pumir, V. Nikolski, M. Homing, A. Isomura, K. Agladze, K. Yoshikawa, R. Gilmour, E. Bodenschatz, V. Krinsky
  • Journal Title: Physical Review Letters 99 Pages: 2081011-4
  • Peer Reviewed
• [Journal Article] Visualization of Different Pathways of DNA Release from Interpolyelectrolyte Complex (2007)
  • Author(s): M. Asad Ayoubi, A. A. Zinchenko, O. E. Philippova, A. R. Khokhlov, K.
  • Journal Title: J. Phys. Chem. B 111 Pages: 10853-10857
  • Peer Reviewed
• [Journal Article] Blebbing Dynamics In An Oil-water-surfactant System Through The Generation and Destruction of A Gel-like Structure (2007)
  • Author(s): Y. Sumino, H. Kitahata, H. Seto, K. Yoshikawa
  • Journal Title: Physical Review E 76 Pages: 552021-4
  • Peer Reviewed
• [Journal Article] Dynamic-Processes in Endocytic Transformation of a Raft-Exhibiting Giant Liposome (2007)
  • Author(s): T. Hamada, Y. Miura, K. Ishii, S. Araki, K. Yoshikawa, M. Vestergaard, M. Takagi, a.
  • Journal Title: J. Phys. Chem. B, 111 Pages: 10853-10857
  • Peer Reviewed
• [Journal Article] Weak Interaction Induces an ON/OFF Switch, whereas strong Interaction Causes Gradual Change: Folding Transition of a Long Duplex DNA Chain by Poly-L-lysine, Biomacromolecules (2007)
  • Author(s): T. Akitaya, A. Seno, T. Nakai, N. Hazemoto, S. Murata, K. Yoshikawa
  • Journal Title: Biomacromolecules 8 Pages: 273-278
  • Peer Reviewed
• [Journal Article] Regular self-motion of a liquid droplet powered by the chemical marangoni effect (2007)
  • Author(s): K. Nagai, Y. Sumino, K. Yoshikawa
  • Journal Title: Colloid. Sur. B: Biointerfaces 56 Pages: 197-200
  • NAID: 120000896367
  • Peer Reviewed
• [Journal Article] Dynamical Calling Behavior Experimentally Observed in Japanese Tree Frogs (Hyla japonica) (2007)
  • Author(s): I. Aihara, S. Horai, H. Kitahata, K. Aihara, K. Yoshikawa
  • Journal Title: IEICE Transactions E90-A(10) Pages: 2154-2161
  • NAID: 110007540886
  • Peer Reviewed
• [Journal Article] Weak Interaction Induces an ON/OFF Switch, whereas Strong Interaction Causes Gradual Change : Folding Transition of a Long Duplex DNA Chain by Poly-L-lvsine (2007)
  • Author(s): T.Akitaya, A.Seno, T.Nakai, N.Hazemoto, S.Murata, K.Yoshikawa
  • Journal Title: Biomacromolecules 8 Pages: 273-278
• [Journal Article] Spontaneous Transfer of Phospholipid-Coated Oil-in-Oil and Water-in Oil Micro-Droplets through Oil/Water Interface (2006)
  • Author(s): A.Yamada, T.Yamanaka, T.Hamada, M.Hase, K.Yoshikawa, D.Baigl
  • Journal Title: Langmuir 22 Pages: 9824-9828
• [Journal Article] Transport of a cell-sized phospholipid micro-container across water/oil interface (2006)
  • Author(s): M.Hase, A.Yamada, T.Hamada, K.Yoshiikawa
  • Journal Title: Chemical Physics Letters 426 Pages: 441-444
• [Journal Article] cell-free protein synthesis at high temperatures using the 1ysate of a hyperthermohile (2006)
  • Author(s): T.Endon, T.Kanai, Y.Sato, D.V.Liu.K.Yoshikawa, H.Atomi, T.Imanaka
  • Journal Title: Journal of Biotechnology 126 Pages: 186-195
• [Presentation] 荷電リン脂質系が2次元界面上に形成するマイクロメートルスケールのネットワーク構造 (2012)
  • Author(s): 伊藤弘明、柳澤実穂、市川正敏、吉川研一
  • Organizer: 日本物理学会第67回年次大会
  • Place of Presentation: 関西学院大学西宮上ケ原キャンパス
  • Year and Date: 2012-03-26
• [Presentation] 振動場が誘起する水平面内の回転運動に関する数理モデル (2012)
  • Author(s): 稲垣紫緒、久保善嗣、吉川研一
  • Organizer: 日本物理学会第67回年次大会
  • Place of Presentation: 関西学院大学西宮上ケ原キャンパス
  • Year and Date: 2012-03-25
• [Presentation] 低線量γ線によるDNA二重鎖切断確率はDNA濃度に顕著に依存する (2012)
  • Author(s): 下林俊典、吉川研一、森利明、吉川祐子
  • Organizer: 日本物理学会第67回年次大会
  • Place of Presentation: 関西学院大学西宮上ケ原キャンパス
  • Year and Date: 2012-03-25
• [Presentation] Direct observation and measurement of thermal fluctuation of single softnano-tubes (2012)
  • Author(s): A.Yamamoto, M.Ichikawa
  • Organizer: Phase Transition Dynamics in Soft Matter : Bridging Microscale and Mesoscale
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2012-02-21
• [Presentation] Stabilization of cardiac conduction via rigidity matching between cells and extracellular matrix (2012)
  • Author(s): M.Horning, K.Yoshikawa
  • Organizer: Phase Transition Dynamics in Soft Matter : Bridging Microscale and Mesoscale
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2012-02-20
• [Presentation] Controlling excitation patterns by minimum electric far field : Experiments and simulation on heterogeneous tissue (2012)
  • Author(s): Marcel Horning, Seiji Takagi
  • Organizer: The 50th Annual Conference of Japanese Society for Medical and Biological Engineering, "Medical and Biological Engineering Advance toward next 50 Years"
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2012-01-10
• [Presentation] Self-propelled motion of a composite induced by interfacial instability : spontaneous symmetry breaking and mode-bifurcation (2012)
  • Author(s): F.Takabatake, N.Magome, M.Ichikawa, K.Yoshikawa
  • Organizer: 2011年度GCOEシンポジウム「階層の連結」
  • Place of Presentation: 京都大学吉田キャンパス
• [Presentation] Dynamics of thermal fluctuation of phospholipid nano-tubes through direct observation (2012)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 2011年度GCOEシンポジウム「階層の連結」
  • Place of Presentation: 京都大学吉田キャンパス
• [Presentation] Spontaneous mode switching of a self-running solid/liquid composite (2011)
  • Author(s): F.Takabatake, N.Magome, M.Ichikawa, K.Yoshikawa
  • Organizer: International Symposium of Complex Systems 2011
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2011-12-02
• [Presentation] Mode bifurcation of bouncing dimer caused by chiral-asymmetry (2011)
  • Author(s): Y.Kubo, S.Inagaki, K.Yoshikawa
  • Organizer: Internaional Symposium of Complex Systems 2011
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2011-12-01
• [Presentation] ライデンフロスト液滴の変形と運動モード分岐 (2011)
  • Author(s): 栗村朋、吉川研一、市川正敏
  • Organizer: 第二回京都ソフトマター研究会
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2011-11-19
• [Presentation] Dependence on the DNA concentration of the probability of double strand breaks : the practical use of a long single-DNA molecule observation (2011)
  • Author(s): 下林俊典、吉川研一、吉川祐子、森利明
  • Organizer: 日本放射線影響学会第54回大会
  • Place of Presentation: 神戸商工会議所会館
  • Year and Date: 2011-11-18
• [Presentation] Network-pattern Formation on the Surface of Micro Water Droplets with Charged Lipids (2011)
  • Author(s): 伊藤弘明、柳澤実穂、市川正敏、吉川研一
  • Organizer: 「細胞を創る」研究会4.0
  • Place of Presentation: 千里ライフサイエンスセンター
  • Year and Date: 2011-10-27
• [Presentation] Network-pattern Formation on the Surface of Micro Water Droplets with Charged Lipids (2011)
  • Author(s): H.Ito, M.Yanagisawa, M.Ichikawa, K.Yoshikawa
  • Organizer: International Symposium on SYNTHESIZING LIFE AND BIOLOGICAL SYSTEMS
  • Place of Presentation: Osaka, Japan
  • Year and Date: 2011-10-25
• [Presentation] Playing with sands : segregation induced by mechanical agitation (2011)
  • Author(s): S.Inagaki, K.Yoshikawa
  • Organizer: Nara Workshop on Fracture and Related Topics
  • Place of Presentation: 奈良女子大学
  • Year and Date: 2011-10-13
• [Presentation] 非チューリング・シナリオ:生物の形態形成の新モデル (2011)
  • Author(s): 吉川研一
  • Organizer: 明治大学先端数理科学研究科開発記念シンポジウム記念講演会
  • Place of Presentation: 明治大学駿河台キャンパス
  • Year and Date: 2011-10-05
• [Presentation] 振動板上における物体のカイラル対称性と運動モード分岐 (2011)
  • Author(s): 久保善嗣、稲垣紫緒、吉川研一
  • Organizer: HMC特別研究会「非線形現象の数理解析」
  • Place of Presentation: 金沢大学角間キャンパス
  • Year and Date: 2011-09-27
• [Presentation] Cell-rigidity recognition of neighboring cells toward the stabilization of cardiac conduction (2011)
  • Author(s): Marcel Horning, S.Kidoaki, T.Kawano, K.Yoshikawa
  • Organizer: The 2nd Mini-Syposium on non-equilibrium dynamics of soft matter-International Workshop on Nonlinear Dynamics in Science
  • Place of Presentation: Kyoto University
  • Year and Date: 2011-09-26
• [Presentation] ガラス基板上に浮遊する液体窒素液滴の自発運動 (2011)
  • Author(s): 栗村朋、吉川研一、市川正敏
  • Organizer: HMC特別研究会「非線形現象の数理解析」
  • Place of Presentation: 金沢大学角間キャンパス
  • Year and Date: 2011-09-26
• [Presentation] 油中ミクロ水滴表面に荷電脂質が形成するネットワーク・パターン (2011)
  • Author(s): 伊藤弘明、柳澤実穂、市川正敏、吉川研一
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-24
• [Presentation] γ線によるDNA二重鎖切断の定量的計測:単一DNA分子測定手法の活用 (2011)
  • Author(s): 下林俊典、吉川研一、吉川祐子、森利明
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-24
• [Presentation] DNA回文配列においてのレトロウイルス特異的挿入反応:反応特異性と十字架構造との定量的相関関係 (2011)
  • Author(s): 劉偉智、鶴山竜昭、吉川研一
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-24
• [Presentation] 高分子溶液のゲル化とカップリングした相分離に対する微小空間効果 (2011)
  • Author(s): 林仁志、市川正敏、吉川研一
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-24
• [Presentation] 振動場における物体のカイラル対称性と運動モード分岐 (2011)
  • Author(s): 久保善嗣、稲垣紫緒、吉川研一｀
  • Organizer: 日本物理学会第67回年次大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-23
• [Presentation] 振動場における物体の運動モード分岐に関するモデル (2011)
  • Author(s): 稲垣紫緒、久保善嗣、吉川研一
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-22
• [Presentation] 液体表面上に浮揚する液体窒素液滴の自発的な並進運動:自発的対称性の破れと運動モード分岐 (2011)
  • Author(s): 栗村朋、吉川研一、市川正敏
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学五福キャンパス
  • Year and Date: 2011-09-22
• [Presentation] Quantitative evaluation of DNA double-strand breaks by low gamma-ray radiation : Application of single DNA observation (2011)
  • Author(s): 下林俊典、吉川研一、吉川祐子、森利明
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 兵庫県立大学姫路書写キャンパス
  • Year and Date: 2011-09-18
• [Presentation] Unique and specific properties of the cell-sized model systems (2011)
  • Author(s): 市川正敏
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 兵庫県立大学姫路書写キャンパス
  • Year and Date: 2011-09-17
• [Presentation] Site-specific integration of retrovirus onto palindromic sequence : Analysis of integration selectivity in relation to DNA local structure (2011)
  • Author(s): W.Liu, K.Yoshikawa, T.Tsuruyama
  • Organizer: 第49回日本生物物理学会年会
  • Place of Presentation: 兵庫県立大学姫路書写キャンパス
  • Year and Date: 2011-09-16
• [Presentation] 直接観察による脂質ナノチューブの動的物性の解明 (2011)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 第51回生物物理若手の会夏の学校
  • Place of Presentation: 関西セミナーハウス
  • Year and Date: 2011-08-25
• [Presentation] 振動板上のねじれ物体の運動モード分岐 (2011)
  • Author(s): 久保善嗣、稲垣紫緒、吉川研一
  • Organizer: 基研研究会2011非平衡系の物理-ミクロとマクロの架け橋
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2011-08-20
• [Presentation] 液体表面上に浮揚する液体窒素液滴の自発的な並進運動:自発的対称性の破れと運動モード分岐 (2011)
  • Author(s): 栗村朋、吉川研一、市川正敏
  • Organizer: 基研研究会2011非平衡系の物理-ミクロとマクロの架け橋
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2011-08-20
• [Presentation] ミクロ水滴上で荷電脂質が形成するネットワーク・パターンとそのダイナミクス (2011)
  • Author(s): 伊藤弘明、柳澤実穂、市川正敏
  • Organizer: 第1回ソフトマター研究会
  • Place of Presentation: キャンパスプラザ京都
  • Year and Date: 2011-08-03
• [Presentation] 揺らぎ運動の直接観察による脂質ナノチューブの動的物性の解明 (2011)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 第1回ソフトマター研究会
  • Place of Presentation: キャンパスプラザ京都
  • Year and Date: 2011-08-03
• [Presentation] Control of activation sites by low-electric far field pacing in excitable media (2011)
  • Author(s): M.Horning, S.Takagi, K.Yoshikawa
  • Organizer: Engineering of Chemical Complexity
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2011-07-07
• [Presentation] Real-World Modeling on Hierarchical Dynamics of Living Matter (2011)
  • Author(s): K. Yoshikawa
  • Organizer: International Conference on Hierarchical Structures in Complex Fluids
  • Place of Presentation: 北京、中国
  • Year and Date: 2011-07-05
• [Presentation] Non-Turing Scenario on Spatio-Temporal Structure Formation (2011)
  • Author(s): K. Yoshikawa
  • Organizer: 7^<th> International Conference on Biological Physics
  • Place of Presentation: San Diego, USA
  • Year and Date: 2011-06-22
• [Presentation] 固液複合体の自発運動:対称性の破れとモード分岐 (2011)
  • Author(s): 高畠芙弥、馬籠信之、市川正敏、吉川研一
  • Organizer: 日本物理学会第66回年次大会
  • Place of Presentation: 新潟大学五十嵐キャンパス
  • Year and Date: 2011-03-28
• [Presentation] 振動板上の物体の運動モード分岐:カイラル対称性の破れと運動の特異性 (2011)
  • Author(s): 久保善嗣、稲垣紫緒
  • Organizer: 日本物理学会第66回年次大会
  • Place of Presentation: 新潟大学五十嵐キャンパス
  • Year and Date: 2011-03-28
• [Presentation] 液体窒素液滴の自発的運動:幾何学的対称性の破れと運動モード分岐 (2011)
  • Author(s): 栗村朋、吉川研一、市川正敏、稲垣紫緒
  • Organizer: 日本物理学会第66回年次大会
  • Place of Presentation: 新潟大学五十嵐キャンパス
  • Year and Date: 2011-03-28
• [Presentation] 脂質マイクロチューブの揺らぎ運動でみる動的物性 (2011)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 日本物理学会第66回年次大会
  • Place of Presentation: 新潟大学五十嵐キャンパス
  • Year and Date: 2011-03-26
• [Presentation] 油水界面上の中性・荷電脂質混合膜上のパターン・ダイナミクス (2011)
  • Author(s): 伊藤弘明、柳澤実穂、市川正敏、吉川研一
  • Organizer: 日本物理学会第66回年次大会
  • Place of Presentation: 新潟大学五十嵐キャンパス
  • Year and Date: 2011-03-26
• [Presentation] 異なる塩濃度の溶液に挟まれた脂質二重膜の相分離 (2011)
  • Author(s): 下川直史
  • Organizer: 第1回京大物理ソフトマター研究会
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2011-03-10
• [Presentation] 界面張力勾配に誘起される自発運動 (2011)
  • Author(s): 高畠芙弥
  • Organizer: 第1回京大物理ソフトマター研究会
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2011-03-10
• [Presentation] Self-propelled motion of a liquid nitrogen droplet : mode bifurcation and analyses (2011)
  • Author(s): 栗村朋
  • Organizer: 第20回「非線形反応と協同現象」研究会
  • Place of Presentation: 鹿児島大学
  • Year and Date: 2011-01-08
• [Presentation] Interactions of Virtual Electrodes-Efficiency of Far-Field Pacing in Heart (2011)
  • Author(s): M.Horning, S.Takagi, K.Yoshikawa
  • Organizer: Far-From-Equilibrium Dynamics 2011
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2011-01-06
• [Presentation] Cross-Talk between Life Science and Physics : Real-world modeling of cell (2011)
  • Author(s): 吉川研一
  • Organizer: Cycle de conferences JSPS Strasbourg et MUFJ 2011-2012
  • Place of Presentation: Strasbourg, France
• [Presentation] 液滴から学ぶ非線形ダイナミクス (2011)
  • Author(s): 吉川研一
  • Organizer: シンポジウム創発と自己組織化-魅惑の非線形
  • Place of Presentation: 九州大学西新プラザ
• [Presentation] Phase separation in charged lipid bilayer membranes between solutions having different ionic strengths (2011)
  • Author(s): N.Shimokawa
  • Organizer: 2010年度GCOEシンポジウム「フロンティア開拓」
  • Place of Presentation: 京都大学吉田キャンパス
• [Presentation] Direct observation of fluctuational motion of a single phospholipid micro-tube (2011)
  • Author(s): A.Yamamoto, M.Ichikawa
  • Organizer: 2010年度GCOEシンポジウム「フロンティア開拓」
  • Place of Presentation: 京都大学吉田キャンパス
• [Presentation] Spontaneous motion of a solid/liquid composite : symmetry breaking and mode bifurcation (2011)
  • Author(s): F.Takabatake, N.Magome, M.Ichikawa, K.Yoshikawa
  • Organizer: 2010年度GCOEシンポジウム「フロンティア開拓」
  • Place of Presentation: 京都大学吉田キャンパス
• [Presentation] 超好熱菌の解剖と応用-新規代謝系の発見- (2010)
  • Author(s): 今中忠行
  • Organizer: 立教大学研究成果報告・シンポジウム文科省私立大学学術高度化推進事業
  • Place of Presentation: 立教大学池袋キャンパス
  • Year and Date: 2010-12-18
• [Presentation] 脂質マイクロチューブのブラウン運動と形状揺らぎ (2010)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 第8回京都大学福井謙一記念センターシンポジウム
  • Place of Presentation: 京都大学福井謙一記念センター
  • Year and Date: 2010-12-03
• [Presentation] Spontaneous mode-selection in the self-propelled motion of a solid/liquid composite driven by interfacial instability (2010)
  • Author(s): F.Takabatake, N.Magome, M.Ichikawa, K.Yoshikawa
  • Organizer: 9th iCeMS International Symposium : "Mesoscale Control and Engineering of Self-Organized and Excitable Systems in Biology and Chemistry"
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2010-12-02
• [Presentation] 超好熱菌の解剖と利用 (2010)
  • Author(s): 今中忠行
  • Organizer: 三菱化学研究奨励基金記念講演会
  • Place of Presentation: 三菱化学研横浜究所
  • Year and Date: 2010-11-24
• [Presentation] 固/液複合体の自発運動モード選択 (2010)
  • Author(s): 高畠芙弥
  • Organizer: 基研研究会2010非平衡系の物理-非平衡ゆらぎと集団挙動
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2010-11-19
• [Presentation] カチオンが誘起する荷電脂質・中性脂質混合系の相分離 (2010)
  • Author(s): 下川直史、菱田真史、瀬戸秀紀、吉川研一
  • Organizer: 第33回溶液化学シンポジウム
  • Place of Presentation: 京都大学吉田キャンパス
  • Year and Date: 2010-11-17
• [Presentation] 1分子計測データに対するパラメータ推定 (2010)
  • Author(s): 宮崎牧人
  • Organizer: 第13回情報論的学習理論ワークショップ
  • Place of Presentation: 東京大学駒場キャンパス
  • Year and Date: 2010-11-06
• [Presentation] 異なる塩濃度の溶液に挟まれた脂質二重膜の遮蔽効果が誘起する相分離 (2010)
  • Author(s): 下川直史、好村滋行、D.Andelman
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-26
• [Presentation] クロマチンの高次構造転移:粗視化モデルからのアプローチ (2010)
  • Author(s): 樋口祐次
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-26
• [Presentation] 異種高分子が形成するミクロ相分離場上でのDNAのブラウン運動 (2010)
  • Author(s): 林仁志
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-26
• [Presentation] 脂質マイクロチューブの揺らぎ運動:構造と物性の相関 (2010)
  • Author(s): 山本暁久、市川正敏
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-25
• [Presentation] 界面不安定性が引き起こす固/液複合体の自発運動のモード選択 (2010)
  • Author(s): 高畠芙弥
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-24
• [Presentation] 振動場上のねじれ物体の運動モード分岐 (2010)
  • Author(s): 久保善嗣、稲垣紫緒
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-24
• [Presentation] Efficiency of Virtual Electrodes in Excitable Media (2010)
  • Author(s): M.Horning, S.Takagi, K.Yoshikawa
  • Organizer: 日本物理学会2010年秋季大会
  • Place of Presentation: 大阪府立大学中百舌鳥キャンパス
  • Year and Date: 2010-09-24
• [Presentation] Difference in the action of Escherichia coli nucleoid proteins, Fis and Dps, on DNA conformation (2010)
  • Author(s): 佐藤祐子、吉川祐子、市川正敏、石浜明、吉川研一
  • Organizer: 第48回日本生物物理学会年会
  • Place of Presentation: 東北大学川内キャンパス
  • Year and Date: 2010-09-20
• [Presentation] Direct observation of dynamical motion of a soft micro-tube (2010)
  • Author(s): A.Yamamoto, M.Ichikawa
  • Organizer: ISSP International Workshop on Soft Matter Physics 2nd week "Biomembranes and Vesicles"
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2010-08-25
• [Presentation] Phase separation of a mixture of charged and neutral lipids on a giant vesicle induced by small cations (2010)
  • Author(s): N.Shimokawa, M.Hishida, H.Seto, K.Yoshikawa
  • Organizer: International symposium on Non-Equilibrium Soft Matter 2010
  • Place of Presentation: Nara, Japan
  • Year and Date: 2010-08-17
• [Presentation] Non-monotonous wrapping transition of a nucleosome induced by torsional stress (2010)
  • Author(s): Y.Higuchi, T.Sakaue, K.Yoshikawa
  • Organizer: International symposium on Non-Equilibrium Soft Matter 2010
  • Place of Presentation: Nara, Japan
  • Year and Date: 2010-08-17
• [Presentation] rownian dynamics of a single phospholipid micro-tube through real-time observation (2010)
  • Author(s): A.Yamamoto, M.Ichikawa
  • Organizer: International symposium on Non-Equilibrium Soft Matter 2010
  • Place of Presentation: Nara, Japan
  • Year and Date: 2010-08-17
• [Presentation] Mode switching of self-propelled motion of a solid/liquid composite under interfacial instability (2010)
  • Author(s): F.Takabatake, M.Ichikawa, K.Yoshikawa
  • Organizer: International symposium on Non-Equilibrium Soft Matter 2010
  • Place of Presentation: Nara, Japan
  • Year and Date: 2010-08-17
• [Presentation] Extremophiles : genetics & application (2010)
  • Author(s): T.Imanaka
  • Organizer: Bio21 Molecular Science & Biotechnology Insutitute, 7th International Symposium of Industrial Microbiology
  • Place of Presentation: Melbourne, Australia
  • Year and Date: 2010-07-02
• [Presentation] 超好熱菌の解剖と産業利用 (2010)
  • Author(s): 今中忠行
  • Organizer: 平成21年度私立大学戦略的研究基盤形成支援事業研究成果報告会
  • Place of Presentation: 日本大学工学部次世代工学技術研究センター
  • Year and Date: 2010-06-17
• [Presentation] 1分子計測における逆問題:タンパク質の内部構造に対するベイズ推定 (2010)
  • Author(s): 宮崎牧人、原田崇広
  • Organizer: 第10回東京大学生命科学シンポジウム
  • Place of Presentation: 東京大学本郷キャンパス
  • Year and Date: 2010-05-01
• [Presentation] Crossover behavior of a single DNA molecule in a quasi-two dimensional system (2010)
  • Author(s): M.Ichikawa, H.Uemura, Y.Kimura
  • Organizer: International Soft Matter Conference 2010
  • Place of Presentation: Granada, Spain
• [Presentation] 増殖期と定常期を模した大腸菌モデル環境における、DNA高次構造変化-ヌクレオイドプロテインFisとDpsによるDNA折り畳みとその顕著な差異 (2010)
  • Author(s): 佐藤祐子、吉川祐子、市川正敏、石浜明、吉川研一
  • Organizer: BMB2010(第33回日本分子生物学会第83回日本生化学会合同大会)
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] Hierarchical Dynamics of Chromatin : Physic Aspects (2009)
  • Author(s): 吉川研一
  • Organizer: Biophysics of Chromatin
  • Place of Presentation: Villa Bosch Studio, Heiderberg, German
  • Year and Date: 2009-02-05
• [Presentation] Discrete transition of DNA : physical and biological significance (2008)
  • Author(s): 吉川研一
  • Organizer: Soft Matter Days
  • Place of Presentation: Gustav-Stresemann-Institutnn, Bonn, Germany
  • Year and Date: 2008-11-14
• [Presentation] Emergence of Exotic Spatio-Temporal Structure under Photon Flux (2008)
  • Author(s): 吉川研一
  • Organizer: The 3rd INTERNATIONAL CONFERENCE ON PHOTO-INDUCED PHASE TRANSITIONS and Cooperative Phenomena(PIPT2008)
  • Place of Presentation: 大阪市立大学杉本キャンパス(大阪)
  • Year and Date: 2008-11-11
• [Presentation] Synthesis of multiple gene products from a single polycistronic mRNA using the Thermococcus kodakaraensis-based translation system (2008)
  • Author(s): T.Kanai, T.Endoh, T.Imanaka
  • Organizer: 2008 International Symposium on Micro-NanoMechatronics and Human Science
  • Place of Presentation: 名古屋大学(愛知)
  • Year and Date: 2008-11-07
• [Presentation] On/Off Switching of Higher-Order Structure in DNA (2008)
  • Author(s): 吉川研一
  • Organizer: International Drug Discovery Science and Technology
  • Place of Presentation: Venue : Loong Palace Hotel, Beijing, China
  • Year and Date: 2008-10-20
• [Presentation] 細胞に学びながら、実空間モデルで遊ぶ Amusing Toy-Model of Living Cell (2008)
  • Author(s): 吉川研一
  • Organizer: 「細胞を創る」研究会1.0「若手研究者の国際ワークショップ」
  • Place of Presentation: 大阪大学吹田キャンパス(大阪)
  • Year and Date: 2008-10-16
• [Presentation] Self-running droplet : mode switching on the autonomous motion (2008)
  • Author(s): 吉川研一
  • Organizer: 5th Dynamics Days Asia Pacific
  • Place of Presentation: 奈良県新公会堂(奈良)
  • Year and Date: 2008-09-11
• [Presentation] Packing a semi-flexible molecular chain, Knots and soft-matter physics : topology of polymers and related topics in physics (2008)
  • Author(s): 吉川研一
  • Organizer: mathematics and biology
  • Place of Presentation: 京都大学基礎物理学研究所湯川記念館(京都)
  • Year and Date: 2008-08-28
• [Presentation] Hydrogel biomaterials by self-assembly of hydrophobized polysaccharides (2008)
  • Author(s): K.Akiyoshi
  • Organizer: 24th International Carbohydrate Symposium
  • Place of Presentation: University of Oslo, Blindern campus, Oslo, Norway
  • Year and Date: 2008-07-28
• [Presentation] New method for reconstitution of membrane proteins to linosome (2008)
  • Author(s): K.Akiyoshi
  • Organizer: 11th Liposome Reserch Days Confrerence
  • Place of Presentation: 横浜シンポジア(神奈川)
  • Year and Date: 2008-07-21
• [Presentation] Self-running droplet : emergence of directional, revolutional and pseudopodial motions (2008)
  • Author(s): 吉川研一
  • Organizer: Fifth International Symposium "Engineering of Chemical Complexity
  • Place of Presentation: The Harnack House, Berlin, Germany
  • Year and Date: 2008-05-25
• [Presentation] Mathematical model and real-world model for the synthesis of cell functions including nonequilibricity of biomembrane and on/off characteristics of giant DNA (2008)
  • Author(s): M.Takinoue, Y.Ma, K.Yoshikawa
  • Organizer: The 17th CDB Meeting-Towards Synthesis of Cells-Reconstruction and Design of Cellular Function
  • Place of Presentation: 理化学研究所(兵庫)
• [Presentation] Self-emergence of Spatio-temporal Structure and Dyncamic Function (2007)
  • Author(s): 吉川研一
  • Organizer: International Workshop on Natural Computing
  • Place of Presentation: 名古屋大字
  • Year and Date: 2007-12-13
• [Presentation] Cross-Talk between Life Science and Physical Science: DNA, Motor, Computation, etc(生命科学と物理科学のキャッチボール:情報・運動・制御の視点から) (2007)
  • Author(s): 吉川研一
  • Organizer: 分子生物学会・生化学学会合同大会
  • Place of Presentation: パシフィコ横浜ヨコハマグランドインターコンチネンタルホテル
  • Year and Date: 2007-12-11
• [Presentation] 紐を折りたたんでナノ秩序構造を創り出す:DNAの実験と理論による一般化 (2007)
  • Author(s): 吉川研一
  • Organizer: 物性研究所短期研究会「物性化学のフロンティア2007」
  • Place of Presentation: 東京大学柏キャンパス物性研究所
  • Year and Date: 2007-11-22
• [Presentation] Lipid-tubular network formation for biochemical reaction (2007)
  • Author(s): 野村慎一郎, 秋吉一成
  • Organizer: Int. Symp. Micro-Nanomechatronics & Human Science (MHS2007)
  • Place of Presentation: 名古屋大学
  • Year and Date: 2007-11-12
• [Presentation] Modeling of Living Cell: Autonomous Motion, Micro-Reactor and Response to the Environment (2007)
  • Author(s): 吉川研一
  • Organizer: IEEE/RST International Conference on Intelligent Robots and Systems
  • Place of Presentation: Sheraton Hotel, San Diego, CA, USA
  • Year and Date: 2007-10-31
• [Presentation] Central carbon metabolism in the hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1 (2007)
  • Author(s): 今中忠行
  • Organizer: Thermophiles 2007, 9th International Conference on Thermophiles Research
  • Place of Presentation: Bergen, Norway
  • Year and Date: 2007-09-26
• [Presentation] 動的細胞機能の実空間モデリング (2007)
  • Author(s): 吉川研一
  • Organizer: 日本機械学会創立110周年記念2007年度年次大会
  • Place of Presentation: 関西大学
  • Year and Date: 2007-09-10
• [Presentation] Hierarchical Structural Dynamic of Chromatin : Modeling from physics (2007)
  • Author(s): 吉川研一
  • Organizer: ICC-2007 Amsterdam 16th International Chromosome Conference Amsterdam RAI Exhibition and Congress Centre
  • Place of Presentation: AmstHUdDm、NHthHUlDnds
  • Year and Date: 2007-08-27
• [Presentation] Novel Hypothesis on the Self-Regulation of Genetic Information: Scenario from One-Dimensional DNA into Spatio-Temporal Order (2007)
  • Author(s): 吉川研一
  • Organizer: The International Workshop on Complex Systems and Networks
  • Place of Presentation: Guilin BUDvo HotHl、桂林、中国
  • Year and Date: 2007-07-19
• [Presentation] ナノゲル架橋ハイブリッドゲルの特性と機能 (2007)
  • Author(s): 秋吉一成
  • Organizer: 07-1高分子基礎物性研究会
  • Place of Presentation: 東京工業大学百年記念館
  • Year and Date: 2007-06-13
• [Book] Construction of an In Vitro Model of a Living Cellular System (2011)
  • Author(s): K. Yoshikawa, S. M. Nomura, K. Tsumoto and K. Takiguchi
  • Publisher: Springer
• [Book] 細胞の自己組織化に物理の視点から迫る (2011)
  • Author(s): 吉川研一, 岩城貴史
  • Publisher: パリティ
• [Book] 酵素の開発と応用技術 (2011)
  • Author(s): 今中忠行(監修)
  • Total Pages: 309
  • Publisher: シーエムシー出版
• [Book] Elucidation of Single Molecular Observation of a Giant DNA (2010)
  • Author(s): C. Shew and K. Yoshikawa
  • Publisher: World Scientific Publishing Company
• [Book] UNDERSTANDING SOFT CONDENSED MATTER VIA MODELING AND COMPUTATION (2010)
  • Author(s): C.Shew, K.Yoshikawa(分担執筆)
  • Total Pages: 30
  • Publisher: World Scientific Publishing Company
• [Book] Single DNA Molecules : Compaction and Decomposition : 第三章 DNA Interactions with Polymers and Surfactants 担当(A.Zinchenko, O.A.Pyshkina, A.V.Lezov, V.G.Sergeyev, K.Yoshikawa) (2008)
  • Author(s): R.Dias, B.Lindman Ed
  • Total Pages: 416
  • Publisher: John Wiley & Sons
• [Book] 自己組織化ハンドブック:序論自己組織化とは--化学担当(吉川研一) (2008)
  • Author(s): 国武豊喜監修
  • Total Pages: 940
  • Publisher: NTS出版
• [Book] ナノゲルキャリア:第五章機能性DDSキャリアの製剤設計担当(佐々木喜浩, 秋吉一成) (2008)
  • Author(s): 岡田弘晃監修
  • Total Pages: 321
  • Publisher: シーエムシー出版
• [Book] 次世代医療のための高分子材料工学 (2008)
  • Author(s): 秋吉一成, 岸田晶夫監修
  • Total Pages: 286
  • Publisher: シーエムシー出版
• [Book] 微生物増殖学の現在・未来:第5章ストレスと培養担当(今中忠行) (2008)
  • Author(s): 福井作蔵, 秦野琢之編
  • Total Pages: 480
  • Publisher: 地人書館
• [Book] Thermophiles : Biology and technology at high temperatures : 第十三章 Targeted gene disruption as a tool for establishing gene function in hyperthermophilic archaea 担当(H.Atomi, T.Imanaka) (2008)
  • Author(s): F.Robb, G.Antranikian, D.Grogan, A.Driessen編
  • Total Pages: 368
  • Publisher: CRC Press
• [Remarks] ホームページ(代表者吉川研一関係)
  • URL: http://www.chem.scphys.kyoto-u.ac.jp/index_j.html
• [Remarks]
  • URL: http://www.chem.scphys.kyoto-u.ac.jp/index_j.html
• [Remarks]
  • URL: http://www.yklab.jp/
• [Patent(Industrial Property Rights)] 定電場によるマイクロサイズの物体の輸送および力学的仕事の取り出し (2009)
  • Inventor(s): 吉川研一,瀧ノ上正,浩厚見悠
  • Industrial Property Rights Holder: (出願人)独立行政法人科学技術振興機構
  • Filing Date: 2009-02-20