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In vivo dynamic sensing by near infrared mechanoluminescence probe.

Research Project

Project/Area Number 18H01453
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 21030:Measurement engineering-related
Research InstitutionSaga University

Principal Investigator

Ueno Naohiro  佐賀大学, 理工学部, 教授 (50356557)

Co-Investigator(Kenkyū-buntansha) 徐 超男  国立研究開発法人産業技術総合研究所, エレクトロニクス・製造領域, 総括研究主幹 (70235810)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2020: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Keywords応力発光体 / 近赤外 / 応力分布 / 主成分分析 / 近赤外光 / 表面修飾 / 軌道平滑化 / 耐水性付与 / 応力発光 / 生体の力学情報 / インプラント / メカノルミネッセンス / 耐水性
Outline of Final Research Achievements

Near-infrared mechanoluminescent materials that emit near-infrared rays (800-1400 nm) with high biotransparency have been applied to biosensing. At first, we focused on the correlation between the mechanoluminescent intensity and the time. A new principal component analysis method that uses both time information and pixel value were developed. Even with high noise levels in the imaging device, the mechanoluminescent components were successfully separated when the mechanoluminescent intensity increased or decreased monotonically over time. In addition, we have developed a new multi-piezo material Sr3Sn2O7: Nd3+, which has an A21am crystal structure. We have succeeded in achieving 10 times higher mechanoluminescent intensity, repeated luminescence, and water resistance than those of conventional materials.

Academic Significance and Societal Importance of the Research Achievements

新たな近赤外応力発光体Sr3Sn2O7:Nd3+は、従来の応力発光体と比較して広帯域の励起波長を示しており、生体に限らず様々な構造物の応力センシングを、マルチバンドで実現する可能性を示している。その応力発光メカニズムをヒントに、さらに新たな応力発光体の可能性も見えている。また、劣悪なノイズレベルから応力発光成分を抽出する手法は、これまで応力発光強度が十分に得られなかった環境での応力センシングを可能にし、応力発光体による応力センシングの適用現場を大きく広げるものとなる。また、この手法を多元的なセンシングデータの解析手法と定義しなおせば、他のセンシング情報解析への応用を期待できる。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (13 results)

All 2021 2020 2019 2018

All Journal Article (5 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 5 results,  Open Access: 2 results) Presentation (8 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Ferroelectric Sr 3 Sn 2 O 7 :Nd 3+ : A New Multipiezo Material with Ultrasensitive and Sustainable Near‐Infrared Piezoluminescence2020

    • Author(s)
      Tu Dong、Xu Chao‐Nan、Kamimura Sunao、Horibe Yoichi、Oshiro Hirotaka、Zhang Lu、Ishii Yoshiharu、Hyodo Koji、Marriott Gerard、Ueno Naohiro、Zheng Xu‐Guang
    • Journal Title

      Advanced Materials

      Volume: 32 Issue: 25 Pages: 1908083-1908083

    • DOI

      10.1002/adma.201908083

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Photoluminescent Ferroelectric LiNb03 Crystals Grown from Mxenes2020

    • Author(s)
      S.Tu, M. Mizohata, G. Sheng, L. Liu, F. Ming, C.N. Xu, D. Tu, X. Zhang, H.N. Alshareef
    • Journal Title

      Advanced Functional Materials

      Volume: 1909843 Issue: 47 Pages: 1-6

    • DOI

      10.1002/adfm.201909843

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Scalable Elasticoluminescent Strain Sensor for Precise Dynamic Stress Imaging and Onsite Infrastructure Diagnosis2018

    • Author(s)
      Liu Linsheng、Xu Chao-Nan、Yoshida Akihito、Tu Dong、Ueno Naohiro、Kainuma Shigenobu
    • Journal Title

      Advanced Materials Technologies

      Volume: 4 Issue: 1 Pages: 1800336-1800336

    • DOI

      10.1002/admt.201800336

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Piezophotonics: From fundamentals and materials to applications2018

    • Author(s)
      Hao Jianhua、Xu Chao-Nan
    • Journal Title

      MRS Bulletin

      Volume: 43 Issue: 12 Pages: 965-969

    • DOI

      10.1557/mrs.2018.296

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Sustainable Mechanoluminescence by Designing a Novel Pinning Trap in Crystals2018

    • Author(s)
      Tu Dong、Hamabe Ryouta、Xu Chao-Nan
    • Journal Title

      The Journal of Physical Chemistry C

      Volume: 122 Issue: 41 Pages: 23307-23311

    • DOI

      10.1021/acs.jpcc.8b06714

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 応力発光体を用いた複雑な構造物の応力分布の可視化2021

    • Author(s)
      溝畑将之、徐超男
    • Organizer
      2021年第68回応用物理学会春季学術講演会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ZnOにおける近赤外応力発光機能の発現2021

    • Author(s)
      岩田隆正、溝畑将之、徐超男
    • Organizer
      公益社団法人日本セラミックス協会 2021年年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マルチピエゾ体 CaZnOS を用いた特異的な近赤外発光特性2020

    • Author(s)
      溝畑将之、徐超男 、上野直広
    • Organizer
      日本セラミックス協会電子材料部会第 40 回電子材料研究討論会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 画素超空間軌跡に基づく時系列応力発光画像解析2019

    • Author(s)
      上野 直広,藤嶋 花織,徐 超男
    • Organizer
      2019年第80回応用物理学会秋季学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Visualization of Stress Distribution from Outside the Biological Tissue by Nearinfrared Mechanoluminescence Material2019

    • Author(s)
      ISHII Yoshiharu, UENO Naohiro, XU Chao-Nan
    • Organizer
      The 13th Pacific Rim Conference of Ceramic Societies
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 近赤外応力発光体を利用した生体内の応力分布の可視化2018

    • Author(s)
      Zhang Lu,川崎悦子,上野直広,徐超男
    • Organizer
      第38回エレクトロセラミックス研究討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 応力発光によるノッチ入り試験片の強度評価2018

    • Author(s)
      石井孝治,上野直広,徐超男
    • Organizer
      第38回エレクトロセラミックス研究討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 近赤外応力発光体を利用した生体内力学情報のセンシング2018

    • Author(s)
      近赤外応力発光体を利用した生体内力学情報のセンシング
    • Organizer
      Zhang Lu、川崎 悦子、兵藤 行志、上野 直広、徐 超男
    • Related Report
      2018 Annual Research Report

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Published: 2018-04-23   Modified: 2022-01-27  

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