| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2021: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
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| Outline of Final Research Achievements |
For the further effective utilization of supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE), it is important to accumulate basic data on the separation behavior in SFC and the solubility in SFE, for which sufficient data have not been available. It is also important to understand the mechanisms of separation in SFC and extraction in SFE. Therefore, we obtained data on the separation behavior of various compounds in SFC, constructed a database containing information on molecular descriptors and a separation prediction model, and analyzed the separation mechanism in SFC. Additionally, we developed a new solubility measurement system using the SFE-SFC-FRC (fraction collector) system, obtained solubility data in SFE, constructed a database containing compound information based on molecular descriptors, and developed a solubility prediction model for SFE.
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