| Project/Area Number |
18H01841
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 28050:Nano/micro-systems-related
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| Research Institution | Tottori University (2019-2020)
Tohoku University (2018) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
吉岡 芳親 大阪大学, 生命機能研究科, 特任教授(常勤) (00174897)
芳賀 洋一 東北大学, 医工学研究科, 教授 (00282096)
藤原 俊朗 岩手医科大学, 医学部, 助教 (60405842)
鶴岡 典子 東北大学, 工学研究科, 助教 (70757632)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | MRI / MRS / MEMS / リアルタイムバイオイメージング / 非平面微細加工技術 / 体腔内MRIプローブ / Intraluminal MRI / MRSプローブ / 高磁場MRI |
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| Outline of Final Research Achievements |
An intraluminal magnetic resonance imaging (MRI) probe holds promise to achieve a higher resolution image of a small pathological lesion than conventional external probes. Such an intraluminal probe requires precise resonant frequency tuning to 500 MHz and impedance matching to 50 Ω, if used for instance in a 11.7-T scanner which can realize a real-time bio-imaging. Designed coil which has higher self-resonance frequency has been fabricated utilizing our developed non-planar photofabrication techniques, and an electrical characteristic has been evaluated. Measured self-resonant frequency of the MRI coil was around 800 MHz and it is higher enough to realize a higher resolution MRI.
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| Academic Significance and Societal Importance of the Research Achievements |
当該研究により実現できる超高分解能なMRIはこれまで解明できていない体内深部における早期がんの発見につながるだけでなく、生体の神経活動などリアルタイムバイオイメージングの実現にもつながる。この様に医療デバイスだけでなく、生体内部における生理学的な減少を解明する取組であり、非平面微細加工技術や小型実装技術がブレークスルー技術である。
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