| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2022: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2021: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2019: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
|
|---|
| Outline of Final Research Achievements |
This study aims to construct a functionally integrated Organs-on-a-chip as a higher-order in vitro system to complement the discrepancy between in vivo and in vitro, which can reproduce nonlinear responses due to tissue/organ interactions and observe such phenomena. In this study, we have developed a design method of organs-on-a-chip that reproduces nonlinear responses by combining multiple organ models with enhanced physiological organ functions based on physiological parameters using organs-on-a-chip technology, and a real-time measurement method of the dynamics of each organ model within a single fluid network. We developed a method for real-time measurement of the dynamics of each organ model in a fluid network.
|
