| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2019: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2018: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Outline of Final Research Achievements |
The improved spatial resolution of the scanning electrochemical microscope (SECM) has created a necessity to revisit previously overlooked information. It is extremely important to examine and clarify in detail the interaction between the probe and the substrate, which has become apparent due to the improvement in spatial resolution, and the surface charge on the probe and the sample surface. In this research project, the correlation between the topography and the electrochemical image obtained by SECM system. We will develop a scanning probe microscopy (SPM) system that enables comprehensive gene expression analysis by acquiring high-resolution images of tissue models and collecting trace amounts of samples from the targeted cells. The changes in the imaging data over time will be recorded by SPM and optical microscope observation.
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