Development of AIE dye for bioimaging and organic materials
| Project/Area Number |
18H02045
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 35030:Organic functional materials-related
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2020: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 凝集誘起発光 / 蛍光 / 光物理過程 / 消光 / 無輻射失活 / スチルベン / 発光材料 / センサー / 蛍光色素 / アントラセン / 光機能材料 / 円錐交差 |
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| Outline of Final Research Achievements |
Aggregation-induced emission (AIE) dyes, which quench fluorescence in solution and emit strongly in the solid state, have been used in a variety of applications for biomolecular imaging and solid-state luminescent materials. We focused on stilbenes, which are known to undergo large structural changes around their double bonds after irradiation. We designed an aggregation-induced luminescent dye by means of "bridged stilbene" with a alkylene chain around the double bond. We developed the bridged stilbenes BPST[7] and DPB[7], which demonstrate excellent AIE behavior.
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| Academic Significance and Societal Importance of the Research Achievements |
液中で消光し、固体状態で強く発光する凝集誘起発光（AIE）色素は、生体分子イメージングや固体発光材料への多彩な応用が進められている。しかし、その分子設計法は未開拓な部分が多く、実在系で計算から合成・物性検討まで行った例はほとんど知られていなかった。本研究により、円錐交差に着目し、溶液中で無輻射失活をデザインできれば、合理的にAIE色素が設計できることがわかった。
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Report
(4 results)
Research Products
(15 results)
