| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
The rare actinomycete Actinoplanes missouriensis grows filamentous on agar media and produces a number of terminal sporangia, each containing hundreds of spores. When the sporangium is immersed in water, the sleeping spores awaken and induce sporangium dehiscence to release the spores into the water. The spores become zoospores that can swim fast in water. The aim of this research project is to reveal the ingenious survival strategies of microbial cells by elucidating the molecular basis of the complex morphological differentiation of this bacterium. The multifaceted analyses of the regulation of formation, dormancy, awakening, and motility of motile spores have provided many insights into the regulatory mechanisms of gene expression that underlie the complex morphological differentiation.
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