Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2019: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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Outline of Final Research Achievements |
With the improvement for evaluation of animal behavior, the methods for measurement of motivation to act and fatigue in which the will for action declined were developed. Using optogenetically modified mice whose neuronal activities can tissue-specifically be modulated with light, the pivotal roles of brain reward system for the will for action was demonstrated. The diet that increased the endurance capability and spontaneous motor activities in mice was classified into A) enhancer of exercise ability and B) contributor of formation and maintenance of the motivation to exercise judging from their mechanism of action.
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