| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2020: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Outline of Final Research Achievements |
To invade host plants, Colletotrichum orbiculare needs to develop appressoria pigmented with melanin. However, on nonhost plants, the pathogen’s appressoria fail to develop invasive hyphae because of strong defense responses of the nonhost plants, implying the importance of plant immunity suppression by effectors at this infection stage. In this study, we first focused on one effector that is highly expressed at this invasion stage and is involved in the virulence of C. orbiculare. We revealed the ability of this virulence effector for plant immunity suppression and localization of the effector inside plant cells. Also, based on RNA sequencing of multiple C. orbiculare isolates for selection of virulence effector candidates and subsequent targeted gene disruption of the candidates, three novel virulence effector genes of C. orbiculare have been discovered.
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