| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2019: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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| Outline of Final Research Achievements |
To unveil the essential biological processes of living organisms, it is crucial to elucidate these molecular mechanisms. Protein translocation across the membrane is a fundamental mechanism in all living cells. In a model organism, Escherichia coli, a supramolecular protein complex including the membrane protein complex SecYEG is involved in the protein translocation. In this study, we tried to elucidate the structure and function of the supramolecular protein complex by X-ray crystallography, cryo-electron microscopy, and atomic force microscopy.
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