| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2020: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
|
|---|
| Outline of Final Research Achievements |
Rhodopsin is a photoreceptive membrane protein distributed in the three biological domains of organisms (i.e., eukaryotes, eubacteria, and archaea), and controls the various functions through photo-energy conversion. In addition, it is utilized as a tool for optogenetics, which is a method for controlling biological activity by light. However, the most of molecules are not analyzed so far. On the basis of the background, the purpose of this study is to "explore the diversity of rhodopsin and pursue its potential". We explored the diversity by expression / purification (1. search) and precise analysis (2. analysis) of uncharacterized rhodopsins. We also pursued the possibility of novel optogenetic tools (3. application).
|
