| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2019: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2018: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Outline of Final Research Achievements |
The aim of this project was to demonstrate the concept that "morphogenetic mechanisms specific to a group of animals, in which common trans-regulatory sequences act, give rise to synapomorphy" in the evolutional process of acquisition, loss and convergence. Focusing on birds for which a wide range of embryos and whole genome sequences are available (as our own systems), a method was used in which candidate sequences and genes were narrowed down using a combination of comparative genome analysis and RNAseq. Functional analyses using multiple avian embryos and other vertebrate embryos was performed. We obtained and analyzed the trans-regulatory sequences and their neighboring genes that may have led the convergent web formation in birds. We also studied fish and proposed a novel hypothesis on the acquisition of a novel trait, fin, in vertebrates.
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