Multi-dimensional studies on structure and dynamics plasticity of the VNS-regulon governing xylem cell differentiation
| Project/Area Number |
18H02466
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 44030:Plant molecular biology and physiology-related
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
Demura Taku 奈良先端科学技術大学院大学, デジタルグリーンイノベーションセンター, 教授 (40272009)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2019: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2018: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Keywords | メタボローム解析 / 化学生物学的解析 / 順遺伝学 / ユビキチン化 / 進化的変遷 / 木部細胞分化 / 転写ネットワーク / マルチオミクス / HDAC阻害剤 / 蛍光相関分光法 / 道管 / 遺伝子発現制御ネットワーク / 進化 / オミクス解析 / ケミカルバイオロジー |
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| Outline of Final Research Achievements |
In this study, we analyzed in detail the structure and dynamic plasticity of the VNS regulon, a gene expression regulatory system that plants have evolutionarily developed to optimize the function of water conduction and body-support by vascular xylem cells, in a multilayered approach. The results revealed that 1) degradation of a group of proteins is important for the optimization of xylem cell functions, 2) the cell cycle and intracellular environment are deeply involved in the regulation of xylem cell differentiation, and 3) the basic structure of the VNS regulon is conserved in a moss (Sphagnum palustre) and a conifer (Pinus taeda).
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| Academic Significance and Societal Importance of the Research Achievements |
本研究が対象とする木部細胞は木質バイオマスの本体であり、本研究で得られた成果をもとに木質バイオマスの高度利用（バイオエタノール変換、高エネルギー化）に向けた木質改良につながる点で社会的な意義をもつ。また、本研究が扱う「VNSレギュロン」は植物における遺伝子発現制御システムの代表例であり、この解析で得られた知見と解析手法が他の様々な局面で起動するレギュロンの解析に転用可能である点で学術的な意義は大きい。
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Report
(4 results)
Research Products
(37 results)
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[Journal Article] Interspecific signaling between the parasitic plant and the host plants regulate xylem vessel cell differentiation in haustoria of Cuscuta campestris.2020
Author(s)
Kaga Y., Yokoyama R., Sano, R., Ohtani, M., Demura, T., Kuroha, T., Shinohara, N., Nishitani, K..
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Journal Title
Frontiers in Plant Science
Volume: 11
Pages: 193-193
DOI
Related Report
Peer Reviewed / Open Access
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