| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2020: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2018: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
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| Outline of Final Research Achievements |
This project aims at a better understanding of the mechanisms by which plants integrate microbial and nutritional cues to finetune their immune responses to pathogenic and mutualistic microbes. We show that defense activation through damage-inducible Pep peptides is sensitized under phosphate deficiency, thereby conferring pathogen resistance while accommodating mutualistic microbes for nutrition. Our investigation into the molecular links between immune and phosphate starvation response (PSR) pathways reveals a key role played by PMR4 callose synthase in root callose deposition and phosphate acquisition during PSR. Moreover, genetic studies on PSR pathways via PHR1/PHL1 transcription factors and LPR1/LPR2 ferroxydases further show their critical role in the control of root-associated microbiomes even under nutrient sufficiency. These findings give novel mechanistic insight into the emerging linkage between plant immunity and nutrition deficiency responses.
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