Co-regulation of behavior and pigmentation by neuropeptides in fish
| Project/Area Number |
18H02473
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 44040:Morphology and anatomical structure-related
|
|---|
| Research Institution | University of Toyama |
|---|
Principal Investigator |
Matsuda Kouhei 富山大学, 学術研究部理学系, 教授 (60222303)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
中町 智哉 富山大学, 学術研究部理学系, 講師 (30433840)
今野 紀文 富山大学, 学術研究部理学系, 講師 (50507051)
|
|---|
| Project Period (FY) |
2018-04-01 – 2021-03-31
|
| Project Status |
Completed (Fiscal Year 2020)
|
| Budget Amount *help |
¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2020: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
|
|---|
| Keywords | 脳ペプチド / 生得的行動 / 体色調節 / キンギョ / ゼブラフィッシュ / α黒色素胞刺激ホルモン / コレシストキニン / 行動制御 / メダカ / 生得的行動制御 / 体色制御 / 行動と体色 / αーMSH / CCK / 情動行動 / 摂食行動 |
|---|
| Outline of Final Research Achievements |
In the present study, we found that several neuropeptides (including AVT, CCK and alpha-MSH) related to feeding regulation induces anxiety-like behavior in goldfish and zebrafish. Moreover, we also observed that ICV administration of these peptides may affect body pigmentation, suggesting that some neuropeptides potentially regulate not only food intake and emotional behavior, but also body coloration in these species.
|
| Academic Significance and Societal Importance of the Research Achievements |
本研究により、キンギョとゼブラフィッシュにおいて、摂食行動と情動行動の制御に関与する脳ペプチドの末梢作用、特に体色調節作用との関連性を見出した。行動解析や体色変化の観察が容易な魚類を用いて脳ペプチドによる行動と体色の協調的な制御メカニズムの実体を解き明かそうとする研究は国内外に無く、本研究の成果は脳ペプチドによる行動と体色調節の制御を担う神経基盤の解明に寄与できると考えられる。
|
Report
(4 results)
Research Products
(61 results)
-
-
-
-
-
-
-
-
[Journal Article] Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms2019
Author(s)
Haraguchi S, Kamata M, Tokita T, Tashiro KI, Sato M, Nozaki M, Okamoto-Katsuyama M, Shimizu I, Han G, Chowdhury VS, Lei XF, Miyazaki T, Kim-Kaneyama JR, Nakamachi T, Matsuda K, Ohtaki H, Tokumoto T, Tachibana T, Miyazaki A, Tsutsui K.
-
Journal Title
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
