| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
We aim to form a research field that we name ‘comparative connectomics’ to extract functionally important circuit elements by comparing the neural connection diagrams at a cell-type resolution based on rabies virus-mediated transsynaptic labeling method. Specifically, we examined input neural circuits to hypothalamic oxytocin neurons that secrete the hormone oxytocin in various reproductive states of mice and identified characteristic circuit alterations during pregnancy and lactation in female mice. Also, we established viral-genetic access to oxytocin neurons in ferrets as a model of Carnivora species.
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