| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2021: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2020: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2019: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
|
|---|
| Outline of Final Research Achievements |
For the development of therapeutic agents for infectious diseases from mirror-image natural products and natural resources, several studies were conducted to establish the bioassay systems using mirror-image proteins. We established the preparation protocols of two viral capsid proteins via chemical synthesis and appropriate folding processes. In the course of our development of screening systems for antiviral agents against measles virus, several peptide sequences that exhibit potent antiviral activity were identified. We also established the synthetic process for an enzyme of H. pyroli to provide the functional enzyme after appropriate folding conditions.
|
