| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2020: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Outline of Final Research Achievements |
Although it is important for the maintenance of life in the living body, there is an important signal transduction that can be called a life-and-death balance, which causes illness once abnormally increased due to mutation. The search of bioactive natural products which can modulates these signal transductions have been conducted from subtropical plants and Actinomycetes extract library. The total synthesis of isolated compounds and derivatives. In addition, co-culture method of microorganism and animal cells was developed for activation method of cryptic genes.
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