| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2019: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2018: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Outline of Final Research Achievements |
Visual information processing is achieved by the hierarchical organization of the visual cortex. The mouse visual cortex consists of a primary visual area (V1) and at least nine higher-order visual areas (HVAs) which are functionally tuned to specific features of the visual scene. The functional specialization of HVAs can arise from the interaction between V1 and HVAs. Thus, revealing how information flows between V1 and HVAs is pivotal in understanding the mechanisms of visual perception. However, how HVA-projecting V1 neurons integrate information from their presynaptic neurons remains unknown. Here we mapped the presynaptic networks of AL-projecting or PM-projecting V1 neurons across the whole brain and performed two-photon imaging on AL-projecting and PM-projecting V1 neurons. We found that the projection-target-specific information flows from V1 to HVAs are achieved by the integration of topographically and functionally segregated populations.
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