| Budget Amount *help |
¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2021: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2020: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
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| Outline of Final Research Achievements |
In the highly accurate hypofractionated radiotherapy for moving targets, there are problems inherent in the dose distribution due to changes in the state of organs in the body, as well as the invasiveness of marker implantation and the non-synchronization with the moving targets. In this study, to solve these problems, we generated a statistical respiratory dynamic model describing multi-organ displacement based on a large amount of spatio-temporal image data and developed a non-invasive irradiation technique using the statistical respiratory dynamic model. As a result, we succeeded in generating a highly accurate model from the upper abdomen to the pelvic region. The model was extended to non-invasive irradiation of targets that are not visible on X-ray images, and the usefulness of the proposed method was confirmed.
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