Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2019: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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Outline of Final Research Achievements |
Kidney cells change dramatically their character when they are cultured in dishes. Utilizing recently developed techniques, we generated kidney organoids from mouse kidney progenitor cells and established a method to induce injury and analyze the responses. We previously found that when a portion of kidney cells are injured, other cells are secondarily damaged in a mouse model. In the present study, we found this damage spreading is reproduced in kidney organoids.
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