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Radiogenomics for uterine sarcoma

Research Project

Project/Area Number 18H02944
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 56040:Obstetrics and gynecology-related
Research InstitutionUniversity of Fukui

Principal Investigator

YOSHIDA Yoshio  福井大学, 学術研究院医学系部門, 教授 (60220688)

Co-Investigator(Kenkyū-buntansha) 辻川 哲也  福井大学, 高エネルギー医学研究センター, 准教授 (30380033)
清野 泰  福井大学, 高エネルギー医学研究センター, 教授 (50305603)
岡沢 秀彦  福井大学, 高エネルギー医学研究センター, 教授 (50360813)
水谷 哲也  福井県立大学, 看護福祉学部, 教授 (90322734)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Keywords婦人科腫瘍学 / 子宮肉腫 / 肺転移 / Radiogenomics / 原発巣-転移巣細胞間コミュニケーション / exosome / プラズマゲルソリン / Radiogenomics解析 / 遺伝子プロファイリング / 肺転移マウスモデル / 同所移植法を用いた子宮肉腫・肺転移解析モデル / 画像プロファイル / ゲノムワイド遺伝子発現プロファイル / Radiogenomics法 / 新規の非侵襲的な子宮肉腫診断・治療法 / Texture解析 / 子宮肉腫肺転移解析モデル
Outline of Final Research Achievements

We found that GDF15, Progranulin, and Osteopontin are secreted proteins that are specifically highly expressed in early-stage uterine sarcoma. The regulatory genes of these secreted proteins were also found to be the genes that control exosome secretion. These findings suggest that exosomes are secreted from the primary tumor from an early stage in uterine sarcoma, and that exosomes play a major role in the acquisition of a protective environment in uterine sarcoma through active communication between primary tumor and metastatic tumor cells.In vivo uterine sarcoma "Radiomics" analysis showed that the higher-order textural features of Complementarity and Strength were specific to metastases.These findings suggest that the expression of Complementarity and Strength higher-order texture features in metastases may be a biomarker for the therapeutic effect of anti-esosome administration in uterine sarcoma.

Academic Significance and Societal Importance of the Research Achievements

難治性、子宮肉腫症例に対する新たなバイオマーカーの樹立と子宮肉腫における抗exosome抗体投与における治療効果の可能性が示唆された

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (74 results)

All 2021 2020 2019 2018

All Journal Article (37 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 36 results,  Open Access: 15 results) Presentation (33 results) (of which Int'l Joint Research: 10 results,  Invited: 21 results) Book (4 results)

  • [Journal Article] COVID-19 testing of pregnant women in Japan2021

    • Author(s)
      M.Orisaka, H.Kawamura, Y.Yoshida
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 47 Issue: 1 Pages: 464-464

    • DOI

      10.1111/jog.14567

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diagnostic Value of 18F-FDG PET/MRI for Revised 2018 FIGO Staging in Patients with Cervical Cancer.2021

    • Author(s)
      Tsuyoshi H, Tsujikawa T, Yamada S, Okazawa H, Yoshida Y.
    • Journal Title

      Diagnostics (Basel)

      Volume: 11(2) Issue: 2 Pages: 202-202

    • DOI

      10.3390/diagnostics11020202

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini-review2021

    • Author(s)
      M.Orisaka, Y.Miyazaki, A.Shirafuji, C.Tamamura, H.Tsuyoshi, B.K. Tsang, Y.Yoshida
    • Journal Title

      Reprod Med Biol

      Volume: 20 Issue: 2 Pages: 169-175

    • DOI

      10.1002/rmb2.12371

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer2020

    • Author(s)
      Tsuyoshi Hideaki、Orisaka Makoto、Fujita Yuko、Asare-Werehene Meshach、Tsang Benjamin K.、Yoshida Yoshio
    • Journal Title

      BMC Cancer

      Volume: 20 Issue: 1 Pages: 467-467

    • DOI

      10.1186/s12885-020-06965-4

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Integrated [18F]FDG PET/MRI demonstrates the iron-related bone-marrow physiology.2020

    • Author(s)
      Tsujikawa T, Oikawa H, Tasaki T, Hosono N, Tsuyoshi H, Rahman MGM, Yoshida Y, Yamauchi T, Kimura H, Okazawa H.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 13878-13878

    • DOI

      10.1038/s41598-020-70854-w

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecological cancer2020

    • Author(s)
      H.Tsuyoshi , D.Inoue , T.Kurokawa ,Y. Yoshida
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 46 Issue: 9 Pages: 1661-1671

    • DOI

      10.1111/jog.14391

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of the concordance in HPV type between self- and physician-collected samples using a brush-based device and a PCR-based HPV DNA test in Japanese referred patients with abnormal cytology or HPV infection2020

    • Author(s)
      T.Onuma, T.Kurokawa, A .Shinagawa, Y.Chino, Y .Yoshida
    • Journal Title

      Int J Clin Oncol

      Volume: 25 Issue: 10 Pages: 1854-1860

    • DOI

      10.1007/s10147-020-01727-5

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Implementation of primary HPV testing in Japan2020

    • Author(s)
      T.Kurokawa, Y.Yoshida, O.Iwanari, T.Oishi, T.Kasai, M.Hamada, H.Fujita, H.Fujiwara, M.Yokoyama, N.Sakuragi, J.Kigawa, M.Suzuki
    • Journal Title

      Mol Clin Oncol

      Volume: 13 Pages: 22-22

    • DOI

      10.3892/mco.2020.2092

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The study protocol of the evaluation for the preventive efficacy of the HPV vaccine for persistent HPV16/18 infection in Japanese adult women: the HAKUOH study2020

    • Author(s)
      T.Kurokawa, M.Yamamoto, T.Onuma, H.Tsuyoshi, A.Shinagawa, Y.Chino, Y.Yoshida
    • Journal Title

      BMC cancer

      Volume: 20 Issue: 1 Pages: 1056-1056

    • DOI

      10.1186/s12885-020-07563-0

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer.2020

    • Author(s)
      Tsuyoshi H, Tsujikawa T, Yamada S, Okazawa H, Yoshida Y.
    • Journal Title

      EJNMMI Res

      Volume: 10(1) Issue: 1 Pages: 117-117

    • DOI

      10.1186/s13550-020-00712-3

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diagnostic value of 18F-FDG PET/MRI for staging in patients with endometrial cancer.2020

    • Author(s)
      Tsuyoshi H, Tsujikawa T, Yamada S, Okazawa H, Yoshida Y.
    • Journal Title

      Cancer Imaging

      Volume: 20(1) Issue: 1 Pages: 75-75

    • DOI

      10.1186/s40644-020-00357-4

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 乳癌合併妊娠の産褥早期にみつかった腹膜高分化型乳頭状中皮腫2020

    • Author(s)
      山田 しず佳,黒川 哲司,吉田 好雄
    • Journal Title

      産婦人科の実際

      Volume: 69(1) Pages: 84-87

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of intrahepatic portosystemic shunt and intra-abdominal umbilical vein varix using fetal ultrasonography with HDlive flow imaging2020

    • Author(s)
      H.Kawamura, K.Yashiro, S.Matsuo, T.Okuno, C.Nishino, J.Takahashi, Y.Yoshida
    • Journal Title

      J Med Ultrason (2001)

      Volume: 47(1) Issue: 1 Pages: 143-145

    • DOI

      10.1007/s10396-019-00969-9

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Herlyn-Werner-Wunderlich Syndrome With Cervical Atresia Complicated by Ovarian Endometrioma: A Case Report2020

    • Author(s)
      Y.Miyazaki, M.Orisaka, C.Nishino, T.Onuma, T.Kurokawa, Y.Yoshida
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 46(2) Issue: 2 Pages: 347-351

    • DOI

      10.1111/jog.14175

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel and rapid measurement system for growth differentiation factor-15, progranulin, and osteopontin in uterine sarcoma2020

    • Author(s)
      Maeno Mitsuo、Mizutani Tetsuya、Tsuyoshi Hideaki、Yamada Shizuka、Ishikane Shin、Kawabe Shinya、Nishimura Kengo、Yamada Masami、Miyamoto Kaoru、Yoshida Yoshio
    • Journal Title

      Endocrine Journal

      Volume: 67 Issue: 1 Pages: 91-94

    • DOI

      10.1507/endocrj.EJ18-0572

    • NAID

      130007790959

    • ISSN
      0918-8959, 1348-4540
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] FDG-PET/MRI With High-Resolution DWI Characterises the Distinct Phenotypes of Endometrial Cancer2020

    • Author(s)
      Tsuyoshi H, Tsujikawa T, Yamada S, Chino Y, Shinagawa A, Kurokawa T, Okazawa H, Yoshida Y.
    • Journal Title

      Clinical Radiology

      Volume: 75 Issue: 3 Pages: 209-215

    • DOI

      10.1016/j.crad.2019.10.018

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮体がん(肉腫を含む)の薬物療法2019

    • Author(s)
      吉田 好雄
    • Journal Title

      日本婦人科腫瘍学会雑誌

      Volume: 37(2) Pages: 99-109

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集 数十年先まで見据えた周産期のケア 尿失禁や骨盤臓器脱から女性を守る,分娩時・産後に生じる骨盤臓器脱と予防・介入法2019

    • Author(s)
      知野 陽子,吉田 好雄
    • Journal Title

      助産雑誌

      Volume: 73(4) Pages: 263-267

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 帝王切開術後子宮創部膿瘍の予防戦略:閉鎖式吸引ドレナージ法の有用性2019

    • Author(s)
      佐藤 久美子,西島 浩二,山本 真,玉村 千代,吉田 好雄
    • Journal Title

      日本周産期・新生児医学会雑誌

      Volume: 55(1) Pages: 33-40

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 広汎子宮頸部摘出術を考慮した若年性子宮頸癌患者に子宮内膜癌が重複した1例,A cace of synchronous malignancies of the ceavix and endometrium in a young patient who considered radical trachelectomy2019

    • Author(s)
      伊藤 太郎,河原 和美,佐藤 加奈,品川 明子,銅 愛,黒川 哲司,吉田 好雄
    • Journal Title

      産科と婦人科

      Volume: 86(6) Pages: 773-776

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Predictive Value of 16α-[18F]-Fluoro-17β-Estradiol PET as a Biomarker of Progestin Therapy Resistance in Patients With Atypical Endometrial Hyperplasia and Low-Grade Endometrial Cancer2019

    • Author(s)
      Yamada Shizuka、Tsuyoshi Hideaki、Tsujikawa Tetsuya、Okazawa Hidehiko、Yoshida Yoshio
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 44 Issue: 7 Pages: 574-575

    • DOI

      10.1097/rlu.0000000000002612

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高齢者の婦人科疾患の特徴と問題点,The Real World Situation and Clarify the Problem in Japanese Elderly Women2019

    • Author(s)
      吉田 好雄
    • Journal Title

      日本産科婦人科学会雑誌

      Volume: 71(8) Pages: 1569-1574

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Whole-body bone marrow DWI correlates with age, anemia, and hematopoietic activity.2019

    • Author(s)
      Tsujikawa T, Oikawa H, Tasaki T, Hosono N, Tsuyoshi H, Yoshida Y, Yamauchi T, Kimura H, Okazawa H.
    • Journal Title

      Eur J Radiol.

      Volume: 118 Pages: 223-230

    • DOI

      10.1016/j.ejrad.2019.07.022

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of diagnostic laparoscopy in patients with large cell neuroendocrine carcinoma of the ovary with cancerous peritonitis: case report and review of the literature2019

    • Author(s)
      H.Tsuyoshi, K.Yashiro, S.Yamada, M.Yamamoto, T.Onuma, T.Kurokawa, Y.Yoshida
    • Journal Title

      J Ovarian Res

      Volume: 12(1) Issue: 1 Pages: 95-95

    • DOI

      10.1186/s13048-019-0571-8

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A delayed diagnosis of acute myeloid leukaemia during pregnancy using an old blood cell analyser2019

    • Author(s)
      D.Inoue, K.Nishijima, J.Takahashi, Y.Yoshida
    • Journal Title

      J Obstet Gynaecol

      Volume: 39(8) Issue: 8 Pages: 1173-1174

    • DOI

      10.1080/01443615.2019.1600480

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Current treatment of older patients with recurrent gynecologic cancer2019

    • Author(s)
      Y.Yoshida
    • Journal Title

      Curr Opin Obstet Gynecol

      Volume: 31(5) Issue: 5 Pages: 340-344

    • DOI

      10.1097/gco.0000000000000543

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 8.高齢者再発,特集 どうする 再発婦人科がん2019

    • Author(s)
      吉田 好雄
    • Journal Title

      産科と婦人科

      Volume: 86(10) Pages: 1211-1216

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 胎児共存奇胎において胞状奇胎の局在が周産期予後に及ぼす影響2019

    • Author(s)
      八代 憲司,折坂 誠,川村 裕士,玉村 千代,髙橋 仁,吉田 好雄
    • Journal Title

      日本周産期・新生児医学会雑誌

      Volume: 55(4) Pages: 958-963

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prenatal progressive cardiomegaly and functional pulmonary atresia on one fetus of monochorionic diamniotic twin pregnancy regardless of spontaneous resolution of isolated polyhydramnios.2019

    • Author(s)
      Kawamura H1, Nishijima K, Fujii K, Tamura S, Takahashi J, Yoshida Y
    • Journal Title

      Taiwan J Obstet Gynecol

      Volume: 58(1) Issue: 1 Pages: 51-52

    • DOI

      10.1016/j.tjog.2018.11.009

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The ideal strategy for cervical cancer screening in Japan: Result from the Fukui Cervical Cancer Screening Study.2018

    • Author(s)
      Kurokawa T, Onuma T, Shinagawa A, Chino Y, Kobayashi M, Yoshida Y
    • Journal Title

      Cytopathology

      Volume: 29(4) Issue: 4 Pages: 361-367

    • DOI

      10.1111/cyt.12576

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of retained products of conception using pulsed continuous arterial spin-labeling MRI: clinical feasibility and initial results2018

    • Author(s)
      Kosaka Nobuyuki、Fujiwara Yasuhiro、Kurokawa Tetsuji、Matsuda Tsuyoshi、Kanamoto Masayuki、Takei Naoyuki、Takata Kenji、Takahashi Jin、Yoshida Yoshio、Kimura Hirohiko
    • Journal Title

      Magnetic Resonance Materials in Physics, Biology and Medicine

      Volume: - Issue: 4 Pages: 577-584

    • DOI

      10.1007/s10334-018-0681-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Luteinizing Hormone Facilitates Antral Follicular Maturation and Survival via Thecal Paracrine Signaling in Cattle.2018

    • Author(s)
      Hattori K, Orisaka M, Fukuda S, Tajima K, Yamazaki Y, Mizutani T, Yoshida Y.
    • Journal Title

      Endocrinology

      Volume: 印刷中 Issue: 6 Pages: 2337-2347

    • DOI

      10.1210/en.2018-00123

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular biomarkers for uterine leiomyosarcoma and endometrial stromal sarcoma.2018

    • Author(s)
      Tsuyoshi H, Yoshida Y
    • Journal Title

      Cancer Sci

      Volume: 109(6) Issue: 6 Pages: 1743-1752

    • DOI

      10.1111/cas.13613

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selected PET radiomic features remain the same.2018

    • Author(s)
      Tsujikawa T, Tsuyoshi H, Kanno M, Yamada S, Kobayashi M, Narita N, Kimura H, Fujieda S, Yoshida Y, Okazawa H
    • Journal Title

      Oncotarget

      Volume: 9(29) Issue: 29 Pages: 20734-20746

    • DOI

      10.18632/oncotarget.25070

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] PET-CT画像:読影時にピットフォール,症例検討会で突っ込まれないための“実践的”婦人科画像の読み方2018

    • Author(s)
      津吉 秀昭,吉田 好雄
    • Journal Title

      臨床婦人科産科

      Volume: 72(9) Pages: 855-862

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮筋腫のMRI/PETによる画像診断-特に子宮筋腫との鑑別に関して-,特集 子宮筋腫のすべて2018

    • Author(s)
      津吉 秀昭,吉田 好雄
    • Journal Title

      HORMONE FRONTIER IN GYNECOLOGY

      Volume: 25(2) Pages: 35-40

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] オウム病による国内初の妊産婦死亡例2018

    • Author(s)
      清水 可奈子,西島 浩二,河原 和美,坂野 陽通,吉村 芳修,柳原 格,今村 好章,黒川 哲司,吉田好雄
    • Journal Title

      産婦人科の実際

      Volume: 67(4) Pages: 445-450

    • Related Report
      2018 Annual Research Report
  • [Presentation] 子宮肉腫の術前診断法確立に向けた試み2021

    • Author(s)
      吉田 好雄
    • Organizer
      第62回日本婦人科腫瘍学会学術講演会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん治療について2021

    • Author(s)
      吉田 好雄
    • Organizer
      第2回岡山婦人科腫瘍研究会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん治療2021

    • Author(s)
      吉田 好雄
    • Organizer
      第2回長崎産婦人科学術講演会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 血中GDF15,progranulin,osteopontinの測定による子宮肉腫と子宮筋腫の鑑別2020

    • Author(s)
      水谷 哲也,前野 光生,津吉 秀昭,山田 しず佳,西村 研吾,吉田 好雄
    • Organizer
      第93回日本内分泌学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 卵巣がん治療のup date2020

    • Author(s)
      吉田 好雄
    • Organizer
      第48回北陸産科婦人科学会総会・学術講演会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 子宮肉腫と子宮筋腫を鑑別する新たなバイオマーカーの同定2020

    • Author(s)
      水谷 哲也,津吉 秀昭,山田 しず佳,吉田 好雄
    • Organizer
      第79回日本癌学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 子宮筋腫と子宮肉腫の診断・治療法2020

    • Author(s)
      吉田 好雄
    • Organizer
      令和2年度富山県産科婦人科学会第3回例会・特別講演会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] The efficacy of the co-testing with Cytology and HPV testing in Japan(シンポジウム)2019

    • Author(s)
      T.Kurokawa, T.Onuma, Y.Chino, A.Shinagawa, Y.Yoshida
    • Organizer
      20th International Congress of Cytology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ellular Evaluation of Benign Endometrial Abnormalities Using the Yokohama Reporting System(シンポジウム)2019

    • Author(s)
      T.Kurokawa, A.Shinagawa, T.Onuma, Y.Yoshida
    • Organizer
      20th International Congress of Cytology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Endometrial Glass Slide Workshop(ワークショップ)2019

    • Author(s)
      A.shinagawa, T.Kurokawa, T.Onuma, Y.Yoshida
    • Organizer
      20th International Congress of Cytology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prevalence of CIN2+ in human papillomavirus-negative with abnormal cytology in the Fukui Cervical Cancer Screening study (FCCS) study2019

    • Author(s)
      T.Onuma, T.Kurokawa, A.Shinagawa, Y.Yoshida
    • Organizer
      20th International Congress of Cytology 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] FES mean standardized uptake value is a prognostic marker for patients with endometrial carcinoma2019

    • Author(s)
      S.Yamada, H.Tsuyoshi, Y.Kiyono, T.Tsujikawa, H.Okazawa, Y.Yoshida
    • Organizer
      Society of Nuclear &Molecular Imaging 2019 Annual Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mitochondria-eating protein is essential for sperm function, but not oocyte quality, in in vitro fertilization2019

    • Author(s)
      M.Orisaka, Y.Nakamura, H.Arakawa, Y.Yoshida
    • Organizer
      52nd Annual conference of the Society for the Study of Reproduction(SSR)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Visualization of intrahepatic portosystemic shunt and intraabdominal umbilical vein varix by fetal echocardiography with HDlive Flow imaging2019

    • Author(s)
      H.Kawamura, C.Nishino, K.Yashiro, T.Okuno, C.Tamamura, J.Takahashi, M.Orisaka, Y.Yoshida
    • Organizer
      9th World Congress on Ultrasound in Obstetrics and Gynecology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高齢女性特有の社会背景の変化と特徴と問題点(教育講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      第71回日本産科婦人科学会学術講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 高齢者婦人科がん治療における現状と問題点(特別講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      第61回日本婦人科腫瘍学会学術講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 子宮筋腫と子宮肉腫の鑑別2019

    • Author(s)
      吉田 好雄
    • Organizer
      北信産婦人科医会講演会(特別講演)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん医療(特別講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      婦人科がん治療セミナー(第25回鈴木・産婦セミナー)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん治療(特別講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      第68回三重県生涯教育特別研修セミナー
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん治療:高齢者機能評価と治療方針(特別講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      第12回奈良婦人科腫瘍カンファランス
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 子宮平滑筋肉腫の診断・管理~GCIC-ESGO Rare Tumour Guidelines(2019年案)に基づき~(特別講演)2019

    • Author(s)
      吉田 好雄
    • Organizer
      婦人科Sarcoma Conference in 宮城
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 子宮肉腫と鑑別,PET imaging of estrogen receptors as a diagnostic tool for uterine malignancy2019

    • Author(s)
      吉田 好雄
    • Organizer
      第10回婦人科ホルモン依存性疾患研究会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Radiomics and Radiogenomics for gynecologic oncology, Use of Artificial Intelligence Toolsin Gynecologic Oncology2018

    • Author(s)
      Y.Yoshida
    • Organizer
      第60回日本婦人科腫瘍学会学術講演会・IGCS2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Diagnostic value of bioactive factors from blood sample for the early detection of sarcoma2018

    • Author(s)
      H.Tsuyoshi, Y.Yoshida
    • Organizer
      第60回日本婦人科腫瘍学会学術講演会・IGCS2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Possible role of Mieap-mediated iron-dependent cell death in p53 tumor suppression of human cervical cancer2018

    • Author(s)
      M.Yamamoto, S.Yamada, H.Tsuyoshi, T.Kurokawa, Y.Yoshida
    • Organizer
      第60回日本婦人科腫瘍学会学術講演会・IGCS2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高齢者の周術期管理(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      平成30年度山口県産婦人科医会第2回研修会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 産後から始まる骨盤ケア~骨盤臓器脱とサルコペニア~(教育講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第59回日本母性衛生学会総会・学術集会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 高齢者の癌治療(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第8回久留米周術期管理フォーラム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 高齢者の癌治療(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第12回千葉産婦人科臨床問題研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 高齢者の癌治療(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第316回青森県臨床産婦人科医会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 高齢者のがん治療(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第1回若手世代で婦人科腫瘍診療を考える会~in 四国
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 子宮体がん(肉腫含む)の薬物療法(教育プログラム)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第60回日本婦人科腫瘍学会学術講演会・IGCS2018
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 子宮肉腫の診断(特別講演)2018

    • Author(s)
      吉田 好雄
    • Organizer
      第5回日本婦人科腫瘍学会研修会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Book] 今日の治療指針2020年版 私はこう治療している2020

    • Author(s)
      吉田 好雄,辻川 哲也
    • Total Pages
      2192
    • Publisher
      医学書院
    • ISBN
      9784260039406
    • Related Report
      2019 Annual Research Report
  • [Book] 産科と婦人科 新時代のホルモン療法マニュアル2019

    • Author(s)
      山田 しず佳,津吉 秀昭,吉田 好雄
    • Total Pages
      384
    • Publisher
      診断と治療社
    • Related Report
      2019 Annual Research Report
  • [Book] 産科婦人科臨床シリーズ 6女性ヘルスケア2019

    • Author(s)
      吉田 好雄,津吉 秀昭
    • Total Pages
      384
    • Publisher
      中山書店
    • ISBN
      9784521747668
    • Related Report
      2019 Annual Research Report
  • [Book] 一冊でわかる婦人科腫瘍の画像診断 : モダリティ・解剖・病理・診断・治療フォローアップ・ピットフォール : JSAWI発2019

    • Author(s)
      吉田 好雄
    • Total Pages
      196
    • Publisher
      文光堂
    • ISBN
      9784830631245
    • Related Report
      2019 Annual Research Report

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Published: 2018-04-23   Modified: 2022-01-27  

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