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Assessment of muscle quality and function by electrophysiological techniques

Research Project

Project/Area Number 18H03158
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionChukyo University

Principal Investigator

Watanabe Kohei  中京大学, スポーツ科学部, 教授 (20630990)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2021: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2020: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Keywords運動単位 / 骨格筋 / 運動神経 / サルコペニア / 筋肉量 / 筋収縮特性 / 加齢 / 多チャンネル表面筋電図法 / 高齢者 / 筋収縮様式 / 筋の質 / 筋電図 / 超音波画像 / 骨格筋電気刺激 / 筋電気刺激 / 筋の収縮特性
Outline of Final Research Achievements

This research project developed novel methodologies that we established by using neuromuscular electrical stimulation and high density surface electromyography techniques to assess quality of muscle and neural activation(Tomita, Watanabe et al. Physiol Rep 2020). We applied them to young and older adults to quantify three major determinants of muscle strength, i.e., muscle volume, quality of muscle, and neural activation(Watanabe et al. Physiol Rep 2020, Watanabe et al. J Gerontol, Watanabe et al. Front Nutr 2021). Our novel methodologies could help to understand what factor is major for age-related strength loss and/or what factors is improved by a countermeasure to age-related motor dysfunctions.

Academic Significance and Societal Importance of the Research Achievements

加齢にともなう筋力低下に関連する要因として、「筋肉の量」、「筋肉の質」、「神経活動」の3つが挙げられる。医用画像技術を用いて、「筋肉の量」の定量評価が一般化されつつあり、多くの研究のアウトカムとして用いられてきた。一方、高齢者における筋力低下は「筋肉の量」の低下だけでは説明できないことも指摘されている。本研究課題では、「筋肉の質」および「神経活動」を定量的に評価する方法を確立した。これにより、高齢者1人1人において筋力低下に寄与する要因の特定をすることや各種運動処方や食事介入が作用する要因を明確にすることが可能になると考えている。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (43 results)

All 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (4 results) Journal Article (26 results) (of which Int'l Joint Research: 13 results,  Peer Reviewed: 26 results,  Open Access: 18 results) Presentation (10 results) (of which Int'l Joint Research: 1 results) Remarks (3 results)

  • [Int'l Joint Research] University of Maribor(スロベニア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] University of Maribor(スロベニア)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of Maribor(スロベニア)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Maribor(スロベニア)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Regional neuromuscular regulation within rectus femoris muscle following three-month limb-loaded walking in older adults2022

    • Author(s)
      Narouei Shideh、Akatsu Hiroyasu、Watanabe Kohei
    • Journal Title

      Sports Medicine and Health Science

      Volume: 4 Issue: 1 Pages: 38-43

    • DOI

      10.1016/j.smhs.2021.12.003

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Central Tendon Injury Impairs Regional Neuromuscular Activation of the Rectus Femoris Muscle2021

    • Author(s)
      Kubo Yoshiaki、Watanabe Kohei、Nakazato Koichi、Koyama Koji、Hiranuma Kenji
    • Journal Title

      Sports

      Volume: 9 Issue: 11 Pages: 150-150

    • DOI

      10.3390/sports9110150

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Motor unit firing patterns on increasing force during force and position tasks2021

    • Author(s)
      Kunugi Shun、Holobar Ales、Kodera Tsutomu、Toyoda Heishiro、Watanabe Kohei
    • Journal Title

      Journal of Neurophysiology

      Volume: 126 Issue: 5 Pages: 1653-1659

    • DOI

      10.1152/jn.00299.2021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Unique Characteristics of Quadriceps Muscle Morphology and Function in Older Tennis Players2021

    • Author(s)
      Yoshiko Akito、Beppu Moroe、Chosa Naoki、Watanabe Kohei
    • Journal Title

      Journal of Aging and Physical Activity

      Volume: 27 Issue: 4 Pages: 1-8

    • DOI

      10.1123/japa.2021-0074

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between the degree of pre-synaptic dopaminergic pathway degeneration and motor unit firing behavior in Parkinson's disease patients2021

    • Author(s)
      Nishikawa Y, Watanabe K, Holobar A, Takahashi T, Maeda N, Maruyama H, Tanaka S, Hyngstrom A
    • Journal Title

      Sensors

      Volume: 21 Issue: 19 Pages: 6615-6615

    • DOI

      10.3390/s21196615

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Effect of a Portable Electrical Muscle Stimulation on Brain-Derived Neurotrophic Factor in Elderly People: Three Case Studies2021

    • Author(s)
      Nishikawa Yuichi、Watanabe Kohei、Kawade Shuhei、Maeda Noriaki、Maruyama Hirofumi
    • Journal Title

      Gerontology and Geriatric Medicine

      Volume: 7 Pages: 1-5

    • DOI

      10.1177/23337214211040319

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of hybrid assistive limb gait training on spatial muscle activation patterns in spinal muscular atrophy type III2021

    • Author(s)
      Nishikawa Yuichi、Watanabe Kohei、Orita Naoya、Maeda Noriaki、Kimura Hiroaki、Tanaka Shinobu、Hyngstrom Allison
    • Journal Title

      F1000Research

      Volume: 10 Pages: 214-214

    • DOI

      10.12688/f1000research.50951.2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of arm position on spatial distribution of upper trapezius muscle activity during simulated car driving2021

    • Author(s)
      Watanabe Kohei、Yoshida Takahiro
    • Journal Title

      International Journal of Occupational Safety and Ergonomics

      Volume: 15 Issue: 3 Pages: 1-7

    • DOI

      10.1080/10803548.2021.1929700

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contribution of the peroneus longus neuromuscular compartments to eversion and plantarflexion of the ankle2021

    • Author(s)
      Mendez-Rebolledo Guillermo、Guzmn-Venegas Rodrigo、Valencia Oscar、Watanabe Kohei
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 4 Pages: e0250159-e0250159

    • DOI

      10.1371/journal.pone.0250159

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Impact of home-based squat training with two-depths on lower limb muscle parameters and physical functional tests in older adults2021

    • Author(s)
      Yoshiko Akito、Watanabe Kohei
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-86030-7

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quercetin ingestion modifies human motor unit firing patterns and muscle contractile properties2021

    • Author(s)
      Watanabe Kohei、Holobar Ales
    • Journal Title

      Experimental Brain Research

      Volume: 239 Issue: 5 Pages: 1567-1579

    • DOI

      10.1007/s00221-021-06085-w

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between Oxygen Consumption and Surface Electromyographic Amplitude and Its Variation within Individual Calf Muscles during Walking at Various Speeds2021

    • Author(s)
      Watanabe Kohei、Narouei Shideh
    • Journal Title

      Sensors

      Volume: 21 Issue: 5 Pages: 1748-1748

    • DOI

      10.3390/s21051748

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Fish Protein Ingestion Induces Neural, but Not Muscular Adaptations, Following Resistance Training in Young Adults2021

    • Author(s)
      Watanabe Kohei、Holobar Ales、Uchida Kenji、Mita Yukiko
    • Journal Title

      Frontiers in Nutrition

      Volume: 8

    • DOI

      10.3389/fnut.2021.645747

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Novel Insights Into Biarticular Muscle Actions Gained From High-Density Electromyogram2021

    • Author(s)
      Watanabe Kohei、Vieira Taian Martins、Gallina Alessio、Kouzaki Motoki、Moritani Toshio
    • Journal Title

      Exercise and Sport Sciences Reviews

      Volume: 49 Issue: 3 Pages: 179-187

    • DOI

      10.1249/jes.0000000000000254

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of exercise intensity on metabolic responses on combined application of electrical stimulation and voluntary exercise2021

    • Author(s)
      Watanabe Kohei、Takada Tatsuya、Kawade Shuhei、Moritani Toshio
    • Journal Title

      Physiological Reports

      Volume: 9 Issue: 3

    • DOI

      10.14814/phy2.14758

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of the laterality of motor unit behavior in female patients with Parkinson's disease using high-density surface electromyography.2021

    • Author(s)
      Nishikawa Y, Watanabe K, Holobar A, Maeda N, Maruyama H, Tanaka S.
    • Journal Title

      European Journal of Neuroscience

      Volume: 53 Issue: 6 Pages: 1938-1949

    • DOI

      10.1111/ejn.15099

    • NAID

      120007032037

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] High-density surface electromyography to assess motor unit firing rate in Charcot-Marie-Tooth disease type 1A patients2021

    • Author(s)
      Noto Yu-ichi、Watanabe Kohei、Holobar Ale?、Kitaoji Takamasa、Tsuji Yukiko、Kojima Yuta、Kitani-Morii Fukiko、Mizuno Toshiki、Nakagawa Masanori
    • Journal Title

      Clinical Neurophysiology

      Volume: 132 Issue: 3 Pages: 812-818

    • DOI

      10.1016/j.clinph.2020.11.040

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Novel perspective on contractile properties and intensity‐dependent verification of force?frequency relationship during neuromuscular electrical stimulation2020

    • Author(s)
      Tomita A, Kawade S, Moritani T, Watanabe K
    • Journal Title

      Physiological Reports

      Volume: 8 Issue: 22

    • DOI

      10.14814/phy2.14598

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modulation of neural and muscular adaptation processes during resistance training by fish protein ingestions in older adults.2020

    • Author(s)
      Watanabe K, Holobar A, Mita Y, Tomita A, Yoshiko A, Kouzaki M, Uchida K, Moritani T.
    • Journal Title

      Journal of Gerontology Series A: Biological Sciences

      Volume: 75 Issue: 5 Pages: 867-874

    • DOI

      10.1093/gerona/glz215

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of the combination of whole-body neuromuscular electrical stimulation and voluntary exercise on metabolic responses in human.2019

    • Author(s)
      Watanabe K, Yoshida T, Ishikawa T, Kawade S, Moritani T.
    • Journal Title

      Frontiers in Physiology

      Volume: 10 Pages: 1-8

    • DOI

      10.3389/fphys.2019.00291

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of taping and its conditions on electromyographic responses of knee extensor muscles2019

    • Author(s)
      Watanabe Kohei
    • Journal Title

      Human Movement Science

      Volume: 63 Pages: 148-155

    • DOI

      10.1016/j.humov.2018.12.003

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Resistance Training and Fish Protein Intake on Motor Unit Firing Pattern and Motor Function of Elderly2018

    • Author(s)
      Watanabe Kohei、Holobar Ales、Mita Yukiko、Kouzaki Motoki、Ogawa Madoka、Akima Hiroshi、Moritani Toshio
    • Journal Title

      Frontiers in Physiology

      Volume: 9 Pages: 1-14

    • DOI

      10.3389/fphys.2018.01733

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship Between Toe Clearance Strategy and Regional Regulation of Rectus Femoris Muscle During Swing Phase in Prolonged Walking in Young and Older Adults2018

    • Author(s)
      Watanabe Kohei
    • Journal Title

      Frontiers in Physiology

      Volume: 9 Pages: 1-8

    • DOI

      10.3389/fphys.2018.01274

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Electromyographic analysis of hip adductor muscles in soccer instep and side-foot kicking2018

    • Author(s)
      Watanabe Kohei、Nunome Hiroyuki、Inoue Koichiro、Iga Takahiro、Akima Hiroshi
    • Journal Title

      Sports Biomechanics

      Volume: - Issue: 3 Pages: 1-12

    • DOI

      10.1080/14763141.2018.1499800

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between regional neuromuscular regulation within human rectus femoris muscle and lower extremity kinematics during gait in elderly men2018

    • Author(s)
      Watanabe Kohei、Kouzaki Motoki、Moritani Toshio
    • Journal Title

      Journal of Electromyography and Kinesiology

      Volume: 41 Pages: 103-108

    • DOI

      10.1016/j.jelekin.2018.05.011

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between muscle strength and multi-channel surface EMG parameters in eighty-eight elderly2018

    • Author(s)
      Watanabe Kohei、Kouzaki Motoki、Ogawa Madoka、Akima Hiroshi、Moritani Toshio
    • Journal Title

      European Review of Aging and Physical Activity

      Volume: 15 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s11556-018-0192-z

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] 3軸加速度センサを用いた歩行特徴量による 中・高齢者の運動習慣分析2022

    • Author(s)
      中村早希、増尾 明、佐久間拓人、加藤昇平、渡邊航平、赤津裕康
    • Organizer
      情報処理学会第84回全国大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 足関節外がえし筋の運動単位活動と発揮トルクの変動性評価2021

    • Author(s)
      功刀峻、吉村茜、廣野哲也、渡邊航平
    • Organizer
      第27回日本バイオメカニクス学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 高校生における最大筋力と筋量および運動単位活動との関係2021

    • Author(s)
      吉村茜、功刀峻、廣野哲也、能嶋宏弥、渡邊航平
    • Organizer
      第27回日本バイオメカニクス学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 求心性および遠心性収縮運動による筋疲労時の運動単位動員特性の違い2021

    • Author(s)
      廣野哲也、功刀峻、吉村茜、渡邊航平
    • Organizer
      第27回日本バイオメカニクス学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] トレッドミル歩行中の酸素摂取量と神経筋活動におよぼすアンクルウェイトと歩行速度の影響2021

    • Author(s)
      功刀峻、赤津裕康、渡邊航平
    • Organizer
      第76回日本体力医学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] カフェイン摂取が運動単位の発火パターンに及ぼす影響2021

    • Author(s)
      渡邊航平、功刀峻、Ales Holobar
    • Organizer
      第76回日本体力医学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 高齢者における神経系と筋形態に対するトレーニング適応を食品摂取によってコントロールする試み2019

    • Author(s)
      渡邊航平、Ales Holobar、三田有紀子、富田彩、吉子彰人、神崎素樹、内田健志、森谷敏夫
    • Organizer
      第74回日本体力医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 低強度間欠的骨格筋電気刺激による筋疲労が周波数-張力関係や至適周波数に及ぼす影響2019

    • Author(s)
      富田彩,川出周平,森谷敏夫,渡邊航平
    • Organizer
      第74回日本体力医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Force-frequency curve by NMES is associated with muscle thickness and maximal voluntary contraction for quadriceps femoris.2019

    • Author(s)
      Tomita A, Watanabe K.
    • Organizer
      European Colledge of Sports Science.
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 電気刺激強度が周波数ー張力関係に及ぼす影響2018

    • Author(s)
      富田彩、渡邊航平
    • Organizer
      日本体力医学会
    • Related Report
      2018 Annual Research Report
  • [Remarks] 中京大学スポーツ科学部渡邊航平研究室ホームページ

    • URL

      http://kwatanabe.net/index.html

    • Related Report
      2021 Annual Research Report 2020 Annual Research Report
  • [Remarks] 中京大学渡邊航平研究室のホームページ

    • URL

      http://kwatanabe.net/index.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] 中京大学国際教養学部渡邊航平研究室のホームページ

    • URL

      http://kwatanabe.net/index.html

    • Related Report
      2018 Annual Research Report

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Published: 2018-04-23   Modified: 2023-01-30  

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