| Budget Amount *help |
¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2020: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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| Outline of Final Research Achievements |
Feeding behavior is regulated through multiple physiological mechanisms.But, overconsumption and obesity is observed in many people. Overconsumption is induced by psychosocial factors; little is known how neurobiological factors is involved in overconsumption. In this study, we examined whether binge-like sugar overconsumption in mice was associated with alteration of secretion of a gut hormone and/or brain responsiveness to visceral signals (gut stimulation with nutrient and gut hormone administation). Our data suggest that gut hormone secretion and brain responses to visceral stimulation was altered in mice showing binge-like sugar overconsumption.
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