The mechanism of motoric cognitive risk and dementia
| Project/Area Number |
18H03185
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 59040:Nutrition science and health science-related
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| Research Institution | National Center for Geriatrics and Gerontology |
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Principal Investigator |
Doi Takehiko 国立研究開発法人国立長寿医療研究センター, 老年学・社会科学研究センター, 室長 (60589026)
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2020: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2019: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2018: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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| Keywords | 歩行 / 認知機能 / 高齢者 / 認知症 |
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| Outline of Final Research Achievements |
To investigate the mechanism of motoric cognitive risk syndrome as a risk factor for dementia, we investigated a multifaceted approach using biomarkers and brain imaging indices. The results showed that motoric cognitive risk syndrome was associated with brain imaging indices, as well as biomarkers attributed to them, for a higher risk of dementia.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究の成果より、motoric cognitive risk syndromeが血管性病変やアルツハイマー病理に関連する可能性が示唆された。そのため、それらの病理変化に対し検討されてきた介入方法の中から、どのような方法が適切かを精査し、motoric cognitive risk syndromeに対する介入を検討する必要があると考えられる。
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Report
(4 results)
Research Products
(6 results)
